[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594240":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":31,"centralContacts":36,"locations":43,"responsibleParty":66,"collaborators":41,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":41,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":41,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":41,"overallStatus":46,"whyStopped":41,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"South Valley University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Group of l-carnitine and antioxidant","ACTIVE_COMPARATOR","About 42 male patients suffering from teratozoospermia will take medical treatment (l-carnitine and antioxidant) once daily for 3 months",[13],"Drug: l-carnitine",{"label":15,"type":10,"description":16,"interventionNames":17},"Group of varicocelectomy","About 42 male patients suffering from teratozoospermia will undergo subinguinal varicocelectomy.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Group of Mixed Treatment(varicocelectomy then l-carnitine and antioxidant)","About 42 male patients suffering from teratozoospermia will undergo subinguinal varicocelectomy then adjuvant treatment (l-carnitine and antioxidant) for 3 months.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DRUG","l-carnitine","to compare the efficacy of medical treatment (l-carnitine and antioxidants) versus surgical treatment (varicocelectomy) versus surgical treatment and medical treatment (varicocelectomy with adjuvant medications) on pregnancy rate on varicocele related subfertility patients with isolated teratozoospermia.",[19,9,15],[29,30],"Antioxidants","varicocelectomy",[32],{"name":33,"affiliation":34,"role":35},"Mohammad Sayed Abdel-Kader, Professor","Urology Department, Faculty of Medicine, South Valley University, Qena, Egypt","STUDY_CHAIR",[37],{"name":38,"role":39,"phone":40,"phoneExt":41,"email":42},"Marwan Mohamed Ali Bastawy, Resident","CONTACT","+201066067330",null,"marwan13156@gmail.com",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":41,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"South Valley University Hospital","RECRUITING","Qina","South Valley","Egypt","EG",{"type":52,"coordinates":53},"Point",[54,55],32.72671,26.16418,{"lat":55,"lon":54},[58,62],{"name":59,"role":39,"phone":60,"phoneExt":41,"email":61},"Omar Mohamed El-Saghier, Assist.Prof","+201095421734","Omarelsoqier1983@yahoo.com",{"name":63,"role":39,"phone":64,"phoneExt":41,"email":65},"Atef Fathi Ali, Assist.Prof","+201111380109","ateffathi2010@yahoo.com",{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":41,"oldOrganization":41},"PRINCIPAL_INVESTIGATOR","Marwan Mohamed Ali","Resident of Urology, Faculty of Medicine","100594240","medical-treatment-alone-versus-varicocelectomy-versus-varicocelectomy-and-medical-treatment-100594240",false,"NCT07016867","Medical Treatment Alone Versus Varicocelectomy Versus Varicocelectomy and Medical Treatment","Medical Treatment Alone Versus Varicocelectomy Versus Varicocelectomy and Medical Treatment in Management of Male Subfertility With Isolated Teratozoospermia: A Prospective Randomized Study","Inclusion Criteria:\n\n* Sub-fertile men with clinically palpable varicoceles ( unilateral or bilateral ).\n* Men with teratozoospermia.\n\nExclusion Criteria:\n\n* Recurrent varicoceles.\n* Significant medical diseases as: Hepatic insufficiency.\n* Hypersensitivity to the drugs.\n* Female factor of infertility.","MALE","20 Years","50 Years",{"count":81,"type":82},126,"ESTIMATED","INTERVENTIONAL",[85],"NA","A varicocele is defined as an abnormal venous dilatation and\u002For tortuosity of the pampiniform plexus in the scrotum. Although varicoceles are almost always and more common on the left side, up to 50% of the men with varicocele, have bilateral varicoceles.\n\nVaricocele has a negative impact on spermatogenesis, testicular volume, Standard semen parameters, and fertilization, implantation, and embryo outcomes.",[88],"Teratozoospermia","2025-06-11",{"date":91,"type":92},"2025-06-12","ACTUAL",{"date":94,"type":92},"2024-09-01",{"date":96,"type":82},"2025-08-31",{"name":5,"class":6},1]