[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622203":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":11,"centralContacts":11,"locations":37,"responsibleParty":56,"collaborators":11,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":11,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":40,"whyStopped":11,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Benha University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Group I: (5 mg melatonin)","ACTIVE_COMPARATOR",null,[13],"Drug: Melatonin 5 mg",{"label":15,"type":10,"description":11,"interventionNames":16},"Group II: (10 mg melatonin)",[17],"Drug: Melatonin 10 mg",{"label":19,"type":20,"description":11,"interventionNames":21},"Group III: (Placebo)","PLACEBO_COMPARATOR",[22],"Drug: Placebo",[24,29,33],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"DRUG","Melatonin 5 mg","Group I: (5 mg melatonin): Participants will receive 5 mg of oral melatonin 1 hours before the cesarean section.",[9],{"type":25,"name":30,"description":31,"armGroupLabels":32,"otherNames":11},"Melatonin 10 mg","Group II: (10 mg melatonin): Participants will receive 10 mg of oral melatonin 1 hours before the cesarean section.",[15],{"type":25,"name":34,"description":35,"armGroupLabels":36,"otherNames":11},"Placebo","Group III: (Placebo): Participants will receive an identical placebo tablet 1 hours before the cesarean section.",[19],[38],{"facility":39,"status":40,"city":41,"state":11,"zip":11,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Benha University Hospital","RECRUITING","Banhā","Egypt","EG",{"type":45,"coordinates":46},"Point",[47,48],31.1842,30.45977,{"lat":48,"lon":47},[51],{"name":52,"role":53,"phone":54,"phoneExt":11,"email":55},"Taghreed Sakr, MD degree of anesthesia","CONTACT","00201112723187","taghreed.sakr@fmed.bu.edu.eg",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Taghreed Elshahat Sakr","lecturer of anesthesia","100622203","melatonin-on-post-operative-pain-after-cs-100622203",false,"NCT07380568","Melatonin on Post Operative Pain After CS","The Effect of Preoperative Oral Melatonin on Postoperative Pain Control After Cesarean Section: A Dose Comparison Study","CS","Inclusion Criteria:\n\n* \\- Women aged 18-40 years.\n* Scheduled for elective cesarean section.\n* Ability to provide informed consent.\n\nExclusion Criteria:\n\n* Known hypersensitivity to melatonin or opioids\n* Chronic use of analgesics, sedatives, or antidepressants.\n* History of sleep disorders or psychiatric illness.\n* Complicated pregnancies (e.g., preeclampsia, gestational diabetes).\n* Body mass index (BMI) \\> 35 kg\u002Fm².\n* Emergency cesarean sections.\n* Severe systemic diseases (e.g., liver or kidney dysfunction).","FEMALE","18 Years","45 Years",{"count":72,"type":73},60,"ESTIMATED","INTERVENTIONAL",[76],"NA","The goal of this clinical trial is to learn if melatonin will decrease pain after C.S. The main questions it aims to answer are:\n\nDoes melatonin lower the number of times participants need to use a rescue analgesia? What medical problems do participants have when taking melatonin? Researchers will compare different doses of melatonin to see the ideal dose to decrease pain after C.S.\n\nParticipants will:\n\nTake melatonin 30 min before C.S and will be observed for 24 hours for pain and consumption of other analgesia",[79,80,81],"Pain Management","Pain After Surgery","Cesarean Section Pain",[83],"melatonin and pain after C.S","2026-01-24",{"date":86,"type":87},"2026-02-02","ACTUAL",{"date":89,"type":87},"2025-10-10",{"date":91,"type":73},"2026-04-01",{"name":5,"class":6},1]