[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602025":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":52,"centralContacts":57,"locations":66,"responsibleParty":81,"collaborators":10,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":91,"sex":92,"minAge":93,"maxAge":10,"enrollmentInfo":94,"targetDuration":97,"studyType":98,"phases":10,"briefSummary":99,"conditions":100,"keywords":10,"overallStatus":69,"whyStopped":10,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Norwegian University of Science and Technology","OTHER",[8,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Mild Alzheimer",null,"Patients above 65 diagnosed with Alzheimer's Disease according to appropriate ICD-criterias.",[13,14,15,16,17],"Device: 7T MRI","Device: EEG","Biological: Blood samples","Biological: Stool samples","Diagnostic Test: Neuropsychologic test (MoCA)",{"label":19,"type":10,"description":20,"interventionNames":21},"Controls","Age- and gender-matched control group.",[13,14,15,16,17],[23,30,36,41,47],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DEVICE","7T MRI","Resting and activity-based MRI. Dring activity based MRI, the participant will complete tasks testing semantic memory.",[19,9],[29],"Magnetic Resonance imaging",{"type":24,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"EEG","Resting-state EEG",[19,9],[35],"Electrophysiology",{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":10},"BIOLOGICAL","Blood samples","Blood samples taken for analysis of central blood biomarkers.",[19,9],{"type":37,"name":42,"description":43,"armGroupLabels":44,"otherNames":45},"Stool samples","Stool samples collected to identify distinct gut-microbiota compositions between the groups.",[19,9],[46],"Fecal Speciments",{"type":48,"name":49,"description":50,"armGroupLabels":51,"otherNames":10},"DIAGNOSTIC_TEST","Neuropsychologic test (MoCA)","Map cognition with clinically well-established neuropsychology test",[19,9],[53],{"name":54,"affiliation":55,"role":56},"Axel Sandvig Professor, MD PhD","Norwegian University of Science and Technology (NTNU)","PRINCIPAL_INVESTIGATOR",[58,63],{"name":59,"role":60,"phone":61,"phoneExt":10,"email":62},"Axel Sandvig Professor, MD & PhD","CONTACT","+4745840578","axel.sandvig@ntnu.no",{"name":64,"role":60,"phone":10,"phoneExt":10,"email":65},"Varanann Varathalingam","varananv@ntnu.no",[67],{"facility":68,"status":69,"city":70,"state":71,"zip":72,"country":73,"countryCode":74,"cosmosGeoPoint":75,"geoPoint":80,"contacts":10},"Norwegian University of Sciene and Technology \u002F Norges teknisk-naturvitenskapelige universitet (NTNU)","RECRUITING","Trondheim","Trønderlag","7030","Norway","NO",{"type":76,"coordinates":77},"Point",[78,79],10.39506,63.43049,{"lat":79,"lon":78},{"type":82,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100602025","memory-deterioration-in-alzheimer-disease-100602025",false,"NCT07118137","Memory Deterioration in Alzheimer Disease","Translational Neuroscience CAG for Alzheimer's Disease","MemAD","Inclusion Criteria:\n\n* Confirmed diagnosis based on current ICD criteria for AD or MCI .\n* \\>55years.\n* Norwegian native speaker\n* Lives at home and not in a health institution\n\nExclusion Criteria:\n\n* Patients with severe cognitive impairment that prevents assessment with the selected modalities (planned cut-off: CDR \\> 2).\n* Presence of brain tumors.\n* History of traumatic brain injury.\n* History of cranial surgery.\n* Contraindications to the selected imaging modalities (e.g., 7T MRI or EEG).\n* Diagnosis of other neurodegenerative diseases such as Parkinson's disease or ALS.\n\n  7T MRI contraindications:\n* Large tattoos close to the head region, permanent makeup or unremoveable piercings\n* Certain models of pacemakers (if pacemaker implantet, MRI physicist at 7T-lab will be conferred)\n* Implantet metal in body (clips, stents, prothesis, skrews, plates, teeth etc.)",true,"ALL","55 Years",{"count":95,"type":96},30,"ESTIMATED","1 Year","OBSERVATIONAL","Semantic AD",[101,102,103,104],"Alzheimer Disease","Neurodegenerative Diseases","Magnetic Resonance Imaging","Memory Impairment","2025-08-04",{"date":107,"type":108},"2025-08-12","ACTUAL",{"date":110,"type":108},"2023-10-15",{"date":112,"type":96},"2027-12-31",{"name":5,"class":6},1]