[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590565":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":11,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":11,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":11,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":11,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Xuanwu Hospital, Beijing","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CRT plus Sleep Hygiene Education","EXPERIMENTAL",null,[13],"Behavioral: Cognitive Remediation Therapy plus Sleep Hygiene Education (CRT+SHE)",{"label":15,"type":16,"description":11,"interventionNames":17},"Sleep Hygiene Education Only","ACTIVE_COMPARATOR",[18],"Behavioral: Sleep Hygiene Education Only (SHE)",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"BEHAVIORAL","Cognitive Remediation Therapy plus Sleep Hygiene Education (CRT+SHE)","Participants will receive Cognitive Remediation Therapy (CRT) combined with Sleep Hygiene Education (SHE). CRT includes structured training sessions targeting attention, memory, visuospatial skills, calculation ability, logical reasoning, and language abilities. Sessions will be conducted daily for 50 minutes over 6 weeks. Sleep Hygiene Education will cover standard recommendations to improve sleep behaviors.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Sleep Hygiene Education Only (SHE)","Participants will receive Sleep Hygiene Education (SHE) only, including guidance on adjusting sleep schedules, maintaining healthy sleep environments, minimizing stimulant intake, and managing sleep-related behaviors, without any CRT intervention.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Hongxing Wang, MD & PhD","CONTACT","+86 13911127385","wanghongxing@xwh.ccmu.edu.cn",[36],{"facility":37,"status":38,"city":39,"state":11,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Xuanwu Hospital, Capital Medical University","RECRUITING","Beijing","100053","China","CN",{"type":44,"coordinates":45},"Point",[46,47],116.39723,39.9075,{"lat":47,"lon":46},[50],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},{"type":52,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100590565","memory-training-in-insomnia-with-cognitive-impairment-100590565",false,"NCT06969066","Memory Training in Insomnia With Cognitive Impairment","Effect of Cognitive Remediation Therapy (CRT) for Chronic Insomnia (CI) With Cognitive Impairment","Inclusion Criteria:\n\n1. Meets the diagnostic criteria for Insomnia Disorder according to DSM-5.\n2. Pittsburgh Sleep Quality Index (PSQI) total score \\> 5.\n3. Age ≥ 8 years.\n4. Voluntary participation with signed informed consent.\n5. Meets the cognitive impairment criteria associated with CI:\n\n(1) Right-handedness. (2) Age between 55 and 75 years. (3) Education duration ≥ 12 years. (4) At least junior high school education level; fulfills Petersen's diagnostic criteria for mild cognitive impairment: 1.Subjective complaints of memory decline. 2.Duration of cognitive complaints ≥ 3 months. 3.Assessment scores: Global Deterioration Scale (GDS) rating of stage 1-2; Clinical Dementia Rating (CDR) score of 0-0.5. 4.Memory test scores falling ≥ 1.5 standard deviations below the age- and education-matched norms: MMSE ≥ 24, MoCA \\\u003C 26, Activities of Daily Living (ADL) score \\> 26. 5.Memory impairment as the primary deficit, with relatively preserved functioning in other cognitive domains.\n\n6.Normal daily functional abilities. 7.Exclusion of dementia or any major physical or psychiatric disorders that could impair brain function.\n\nExclusion Criteria:\n\n1. Presence of severe physical illnesses or major psychiatric disorders, or assessed risk of suicide.\n2. Diagnosed or suspected sleep breathing disorders, restless legs syndrome, circadian rhythm sleep disorders, or currently engaged in shift work.\n3. Pregnancy or breastfeeding.\n4. Currently undergoing any form of psychological therapy.\n5. History of infectious diseases such as syphilis or HIV.","ALL","8 Years",{"count":63,"type":64},70,"ESTIMATED","INTERVENTIONAL",[67],"NA","This randomized controlled trial investigates the effects of Cognitive Remediation Therapy (CRT) on chronic insomnia (CI) with mild cognitive impairment.",[70,71,72],"Cognitive Therapy\u002FMethods","Insomnia Chronic","Cognitive Dysfunction","2025-05-25",{"date":75,"type":76},"2025-05-28","ACTUAL",{"date":78,"type":76},"2024-11-01",{"date":80,"type":64},"2025-11-01",{"name":5,"class":6},1]