[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628020":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":22,"locations":32,"responsibleParty":49,"collaborators":10,"id":52,"slug":10,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Ankara Etlik City Hospital","OTHER_GOV",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Follicular Phase Group",null,"Female patients undergoing cholecystectomy under general anesthesia who are classified as being in the follicular phase of the menstrual cycle based on postoperative serum progesterone levels. No experimental intervention will be applied. Intraoperative anesthetic consumption and postoperative nausea and vomiting will be recorded as part of routine perioperative management.",{"label":13,"type":10,"description":14,"interventionNames":10},"Luteal Phase Group","Female patients undergoing cholecystectomy under general anesthesia who are classified as being in the luteal phase of the menstrual cycle according to postoperative serum progesterone levels. No intervention beyond standard clinical care will be performed. Anesthetic drug consumption and postoperative nausea and vomiting outcomes will be documented.",{"label":16,"type":10,"description":17,"interventionNames":10},"Postmenopausal Group","Female patients undergoing cholecystectomy under general anesthesia who are postmenopausal. These patients will receive standard perioperative care. Intraoperative anesthetic requirements and postoperative nausea and vomiting will be assessed and compared with other hormonal status groups.",[19],{"name":20,"affiliation":5,"role":21},"oya çimen, Specialist in Anesthesiology","PRINCIPAL_INVESTIGATOR",[23,28],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"oya Çimen, Specialist in Anesthesiology","CONTACT","+905334494750","oya.cimen@hotmail.com",{"name":29,"role":25,"phone":30,"phoneExt":10,"email":31},"Fethi Gültop, Specialist in Anesthesiology","+905052260067","fethigultop@yahoo.com",[33],{"facility":5,"status":34,"city":35,"state":35,"zip":36,"country":37,"countryCode":10,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Ankara","06170","Turkey (Türkiye)",{"type":39,"coordinates":40},"Point",[41,42],32.85427,39.91987,{"lat":42,"lon":41},[45,48],{"name":46,"role":25,"phone":26,"phoneExt":10,"email":47},"oya çimen, Specialist","oya123cimen@gmail.com",{"name":29,"role":25,"phone":30,"phoneExt":10,"email":10},{"type":21,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"oya Çimen","MD, Specialist in Anesthesiology","100628020",false,"NCT07456202","Menstrual Status, Anesthetic Consumption, and PONV","Impact of Menstrual Phases and Menopause on Intraoperative Anesthetic Consumption and Postoperative Nausea and Vomiting: A Prospective Observational Study","Inclusion Criteria:\n\n* Female patients aged 18 to 65 years\n* American Society of Anesthesiologists (ASA) physical status I-II-III\n* Scheduled for elective laparoscopic cholecystectomy under general anesthesia\n* Willing and able to provide written informed consent\n\nExclusion Criteria:\n\n* Age outside the specified range (younger than 18 or older than 65 years)\n* Male patients\n* American Society of Anesthesiologists (ASA) physical status ≥ IV\n* Severe systemic comorbidities (e.g., significant cardiovascular, hepatic, renal, or pulmonary disease)\n* Conversion from laparoscopic to open cholecystectomy\n* History of alcohol, drug, or substance abuse\n* Visual or hearing impairment interfering with study assessments\n* Current hormone replacement therapy\n* Use of oral contraceptives\n* Preoperative nausea or vomiting\n* History of severe postoperative nausea and vomiting\n* Neurological or psychiatric disorders affecting assessment reliability\n* Hemodynamic instability during surgery\n* Postoperative admission to intensive care unit\n* Acute cholecystitis at the time of surgery\n* Refusal to participate or inability to provide informed consent","FEMALE","18 Years","65 Years",{"count":62,"type":63},120,"ESTIMATED","OBSERVATIONAL","This prospective observational cohort study aims to evaluate the association between menstrual phase (determined by postoperative serum progesterone levels), intraoperative anesthetic consumption, and the incidence and severity of postoperative nausea and vomiting (PONV) in female patients undergoing cholecystectomy. Intraoperative anesthetic requirements will be recorded, and postoperative nausea and vomiting will be assessed using standardized scoring systems.",[67],"Menstrual Cycle",[69,70,71,72],"Anesthetic Consumption","Luteal Phase","Follicular Phase","Postoperative Nausea and Vomiting","2026-04-25",{"date":75,"type":76},"2026-04-30","ACTUAL",{"date":78,"type":76},"2026-03-07",{"date":80,"type":63},"2026-06-15",{"name":5,"class":6},1]