[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100468486":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":34,"centralContacts":38,"locations":47,"responsibleParty":152,"collaborators":154,"id":158,"slug":159,"hasResults":160,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":17,"eligibilityCriteria":164,"healthyVolunteers":160,"sex":165,"minAge":17,"maxAge":166,"enrollmentInfo":167,"targetDuration":17,"studyType":170,"phases":171,"briefSummary":173,"conditions":174,"keywords":176,"overallStatus":50,"whyStopped":17,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":189},{"fullName":5,"class":6},"The University of Texas Health Science Center at San Antonio","OTHER",[8,13,18,22],{"label":9,"type":6,"description":10,"interventionNames":11},"DHA\u002FARA supplement","DHA\u002FARA supplement throughout the duration of the protocol, \"d-on\"",[12],"Dietary Supplement: Enfamil® DHA & ARA Supplement for Special Dietary Use",{"label":14,"type":15,"description":16,"interventionNames":17},"No DHA\u002FARA supplement","NO_INTERVENTION","no DHA\u002FARA supplement throughout the duration of the protocol, \"d-off\"",null,{"label":19,"type":6,"description":20,"interventionNames":21},"DHA\u002FARA initially then no supplement","DHA\u002FARA supplement from enrollment to 31 6\u002F7 weeks post-menstrual age (PMA) then no supplement from 32 to 36 weeks' PMA, \"x- on\u002Foff\"",[12],{"label":23,"type":6,"description":24,"interventionNames":25},"No supplement initially then DHA\u002FARA supplement","No DHA\u002FARA supplement till 31 6\u002F7 weeks' then long-chain polyunsaturated fatty acids (LCPUFA) supplement from 32 to 36 weeks PMA, \"x-off\u002Fon\"",[12],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DIETARY_SUPPLEMENT","Enfamil® DHA & ARA Supplement for Special Dietary Use","Dosage: 60 mg\u002Fkg\u002Fday of DHA and 120 mg\u002Fkg\u002Fday of ARA. Route of administration: enteral tube or by oral syringe",[19,9,23],[33],"DHA\u002FARA Supplement",[35],{"name":36,"affiliation":5,"role":37},"Cynthia Blanco, MD, MSCI-TS","PRINCIPAL_INVESTIGATOR",[39,43],{"name":36,"role":40,"phone":41,"phoneExt":17,"email":42},"CONTACT","210-567-5225","blanco@uthscsa.edu",{"name":44,"role":40,"phone":45,"phoneExt":17,"email":46},"Diana Anzueto Guerra","210-567-5254","anzuetod@uthscsa.edu",[48,69,86,103,111,127,144],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"University of California, Los Angeles (UCLA)","RECRUITING","Los Angeles","California","90404","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-118.24368,34.05223,{"lat":60,"lon":59},[63,66],{"name":64,"role":40,"phone":17,"phoneExt":17,"email":65},"Kara Calkins, MD","KCalkins@mednet.ucla.edu",{"name":67,"role":40,"phone":17,"phoneExt":17,"email":68},"Ashley Dong","AMDong@mednet.ucla.edu",{"facility":70,"status":50,"city":71,"state":72,"zip":73,"country":54,"countryCode":55,"cosmosGeoPoint":74,"geoPoint":78,"contacts":79},"Yale New Haven Hospital","New Haven","Connecticut","06511",{"type":57,"coordinates":75},[76,77],-72.92816,41.30815,{"lat":77,"lon":76},[80,83],{"name":81,"role":40,"phone":17,"phoneExt":17,"email":82},"Sarah Taylor, MD","sarah.n.taylor@yale.edu",{"name":84,"role":40,"phone":17,"phoneExt":17,"email":85},"Tessa Kehoe","tessa.kehoe@yale.edu",{"facility":87,"status":50,"city":88,"state":89,"zip":90,"country":54,"countryCode":55,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Ann & Robert H. Lurie Children's Hospital of Chicago","Chicago","Illinois","60611",{"type":57,"coordinates":92},[93,94],-87.65005,41.85003,{"lat":94,"lon":93},[97,100],{"name":98,"role":40,"phone":17,"phoneExt":17,"email":99},"Daniel Robinson, MD","DTRobinson@luriechildrens.org",{"name":101,"role":40,"phone":17,"phoneExt":17,"email":102},"Jonah Silverglade","jsilverglade@luriechildrens.org",{"facility":104,"status":50,"city":88,"state":89,"zip":90,"country":54,"countryCode":55,"cosmosGeoPoint":105,"geoPoint":107,"contacts":108},"Northwestern University",{"type":57,"coordinates":106},[93,94],{"lat":94,"lon":93},[109,110],{"name":98,"role":40,"phone":17,"phoneExt":17,"email":99},{"name":101,"role":40,"phone":17,"phoneExt":17,"email":102},{"facility":112,"status":50,"city":113,"state":113,"zip":114,"country":54,"countryCode":55,"cosmosGeoPoint":115,"geoPoint":119,"contacts":120},"Weill Cornell Medicine","New York","10021",{"type":57,"coordinates":116},[117,118],-74.00597,40.71427,{"lat":118,"lon":117},[121,124],{"name":122,"role":40,"phone":17,"phoneExt":17,"email":123},"Camilia Martin, MD","camilia.martin@med.cornell.edu",{"name":125,"role":40,"phone":17,"phoneExt":17,"email":126},"Martha Liu","mal4038@med.cornell.edu",{"facility":128,"status":50,"city":129,"state":130,"zip":131,"country":54,"countryCode":55,"cosmosGeoPoint":132,"geoPoint":136,"contacts":137},"University Health System","San Antonio","Texas","78229",{"type":57,"coordinates":133},[134,135],-98.49363,29.42412,{"lat":135,"lon":134},[138,140,142],{"name":139,"role":40,"phone":45,"phoneExt":17,"email":46},"Diana Anzueto Guerra, MS",{"name":141,"role":40,"phone":41,"phoneExt":17,"email":42},"Cynthia Blanco, MD",{"name":143,"role":37,"phone":17,"phoneExt":17,"email":17},"Cynthia L Blanco, MD",{"facility":145,"status":50,"city":129,"state":130,"zip":131,"country":54,"countryCode":55,"cosmosGeoPoint":146,"geoPoint":148,"contacts":149},"University of Texas Health Science Center at San Antonio",{"type":57,"coordinates":147},[134,135],{"lat":135,"lon":134},[150,151],{"name":141,"role":40,"phone":17,"phoneExt":17,"email":42},{"name":44,"role":40,"phone":17,"phoneExt":17,"email":46},{"type":153,"investigatorFullName":17,"investigatorTitle":17,"investigatorAffiliation":17,"oldNameTitle":17,"oldOrganization":17},"SPONSOR",[155],{"name":156,"class":157},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH","100468486","metabolic-mechanisms-induced-by-enteral-dha-and-ara-supplementation-in-preterm-infants-100468486",false,"NCT05380401","Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants","Metabolic Mechanisms Induced by Enteral Docosahexaenoic Acid (DHA) and Arachidonic Acid (ARA) Supplementation in Preterm Infants","Inclusion Criteria:\n\n* born between 25 0\u002F7 and 29 6\u002F7 weeks of gestation\n* less than 48 hours of age at first lipid dose (The cohort is defined by gestational age rather than birth weight to avoid an over-represented sample of growth-restricted infants in birth weight defined cohorts.)\n\nExclusion Criteria:\n\n* serious congenital anomalies\n* conditions at birth that will require surgery prior to discharge\n* imminent death such that withdrawal of intensive care support is anticipated within the first 72 hours after birth","ALL","36 Weeks",{"count":168,"type":169},328,"ESTIMATED","INTERVENTIONAL",[172],"NA","A comprehensive analysis of the impact of exogenous enteral DHA and ARA supplementation on lipid metabolism including the production of downstream derived mediators and how this impacts important biological pathways such as metabolism, inflammation, and organogenic factors.",[175],"Premature",[177,178,179],"infant, premature","fatty acids","nutrition","2025-09-19",{"date":182,"type":183},"2025-09-24","ACTUAL",{"date":185,"type":183},"2023-03-09",{"date":187,"type":169},"2028-04",{"name":5,"class":6},7]