[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561510":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":10,"centralContacts":35,"locations":10,"responsibleParty":45,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":10,"eligibilityCriteria":54,"healthyVolunteers":51,"sex":55,"minAge":56,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":10,"overallStatus":67,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"metabolically healthy non obesity (MHNO)",null,"According to the NCEP ATP III definition, metabolic syndrome is present if three or more of the following five criteria are met: waist circumference over 40 inches (men) or 35 inches (women), blood pressure over 130\u002F85 mmHg, fasting triglyceride (TG) level over 150 mg\u002Fdl, fasting high-density lipoprotein (HDL) cholesterol level less than 40 mg\u002Fdl (men) or 50 mg\u002Fdl (women) and fasting blood sugar over 100 mg\u002Fdl.\n\nObesity was defined as a BMI of ≥ 25.0 kg\u002Fm2 . Patients with a BMI of 18.5-\\\u003C23.0 were considered normal weight; for those with a BMI of 23.0-\\\u003C25.0 were overweight. The patients with normal weight and those who were overweight were collapsed into the non-obesity group.\n\nso this group of patients are metabolically healthy and non obese with BMI 18.5 - \\\u003C25",[13],"Diagnostic Test: 24 hour urinary protein",{"label":15,"type":10,"description":16,"interventionNames":17},"metabolically healthy obesity ( MHO )","According to the NCEP ATP III definition, metabolic syndrome is present if three or more of the following five criteria are met: waist circumference over 40 inches (men) or 35 inches (women), blood pressure over 130\u002F85 mmHg, fasting triglyceride (TG) level over 150 mg\u002Fdl, fasting high-density lipoprotein (HDL) cholesterol level less than 40 mg\u002Fdl (men) or 50 mg\u002Fdl (women) and fasting blood sugar over 100 mg\u002Fdl.\n\nObesity was defined as a BMI of ≥ 25.0 kg\u002Fm2 . Patients with a BMI of 18.5-\\\u003C23.0 were considered normal weight; for those with a BMI of 23.0-\\\u003C25.0 were overweight. The patients with normal weight and those who were overweight were collapsed into the non-obesity group.\n\nso this group of patients are metabolically healthy but they are obese with BMI of ≥ 25.0 kg\u002Fm2",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"metabolically unhealthy non obsesity ( MUNO )","According to the NCEP ATP III definition, metabolic syndrome is present if three or more of the following five criteria are met: waist circumference over 40 inches (men) or 35 inches (women), blood pressure over 130\u002F85 mmHg, fasting triglyceride (TG) level over 150 mg\u002Fdl, fasting high-density lipoprotein (HDL) cholesterol level less than 40 mg\u002Fdl (men) or 50 mg\u002Fdl (women) and fasting blood sugar over 100 mg\u002Fdl.\n\nObesity was defined as a BMI of ≥ 25.0 kg\u002Fm2 . Patients with a BMI of 18.5-\\\u003C23.0 were considered normal weight; for those with a BMI of 23.0-\\\u003C25.0 were overweight. The patients with normal weight and those who were overweight were collapsed into the non-obesity group.\n\nso this group of patients are metabolically unhealthy ( have three or more of metabolic syndrome criteria) and non obese with BMI 18.5 - \\\u003C25",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"metabolically unhealthy obesity ( MUO )","According to the NCEP ATP III definition, metabolic syndrome is present if three or more of the following five criteria are met: waist circumference over 40 inches (men) or 35 inches (women), blood pressure over 130\u002F85 mmHg, fasting triglyceride (TG) level over 150 mg\u002Fdl, fasting high-density lipoprotein (HDL) cholesterol level less than 40 mg\u002Fdl (men) or 50 mg\u002Fdl (women) and fasting blood sugar over 100 mg\u002Fdl.\n\nObesity was defined as a BMI of ≥ 25.0 kg\u002Fm2 . Patients with a BMI of 18.5-\\\u003C23.0 were considered normal weight; for those with a BMI of 23.0-\\\u003C25.0 were overweight. The patients with normal weight and those who were overweight were collapsed into the non-obesity group.\n\nso this group of patients are metabolically unhealthy but they are obese with BMI of ≥ 25.0 kg\u002Fm2",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DIAGNOSTIC_TEST","24 hour urinary protein","proteinuria and renal function impairment will be detected in patients of four groups",[9,15,19,23],[33,34],"kidney function test : urea and creatinine","eGFR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":10,"email":40},"George Armia Abdelmaseih, MBBCh","CONTACT","01092790414","georgearmia12@gmail.com",{"name":42,"role":38,"phone":43,"phoneExt":10,"email":44},"Salah Abdel-Azim Argoon, prof dr","01019683366","argoons@yahoo.com",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","George Armia Ghaly Abdelmaseih","Resident physician at Internal Medicine department","100561510","metabolic-phenotypes-of-obesity-and-diabetic-kidney-disease-in-patients-with-type-2-diabetes-mellitus-100561510",false,"NCT06591104","Metabolic Phenotypes of Obesity and Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus","Inclusion Criteria:\n\n* Type 2 diabetic adult patients admitted at Assiut university hospital divided into 4 groups of metabolic phenotypes according to obesity and metabolic status .\n\nExclusion Criteria:\n\n1. Age less than 18\n2. type 1 diabetes\n3. those with a BMI \\<18.5 kg\u002Fm2\n4. co-existing non-diabetic renal disease\n5. Pregnancy and patients with malignancy\n6. Urinary tract infection","ALL","18 Years",{"count":58,"type":59},71,"ESTIMATED","OBSERVATIONAL","1. Comparison between the 4 groups of metabolic phenotypes of obesity as regard the presence and frequency of DKD\n2. Relation between DKD , obesity (BMI) and metabolic risk factors in patients with type 2 DM",[63,64,65,66],"Diabetic Kidney Disease","Obesity","Metabolic Syndrome","Diabetes Mellitus, Type 2","NOT_YET_RECRUITING","2024-09-07",{"date":70,"type":71},"2024-09-19","ACTUAL",{"date":73,"type":59},"2024-10",{"date":75,"type":59},"2025-10",{"name":5,"class":6}]