[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602656":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":27,"locations":33,"responsibleParty":49,"collaborators":53,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":91,"sex":92,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":98,"studyType":99,"phases":10,"briefSummary":100,"conditions":101,"keywords":104,"overallStatus":108,"whyStopped":10,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"Buzzi Children's Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Permanent congenital hypothyroidism",null,"170 patients in prepubertal age.",[13],"Other: prospective observational study (clinical, hormonal and auxological data)",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy childrens normal weight","170 childrens in prepubertal age.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Healthy childrens overweight\u002Fobese","170 patients in prepubertal age",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"prospective observational study (clinical, hormonal and auxological data)","We collect clinical, hormonal and auxological data and compare them between the two groups.",[15,19,9],[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Valeria Calcaterra, MD","CONTACT","+39 0263631","valeria.calcaterra@unipv.it",[34],{"facility":5,"status":10,"city":35,"state":10,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Milan","20154","Italy","IT",{"type":40,"coordinates":41},"Point",[42,43],12.59836,42.78235,{"lat":43,"lon":42},[46],{"name":47,"role":30,"phone":48,"phoneExt":10,"email":32},"Valeria Calcaterra, Prof, MD","00390263635321",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Valeria Calcaterra","Prof",[54,56,58,61,63,65,67,69,71,73,75,77,79,81],{"name":55,"class":6},"Federico II University",{"name":57,"class":6},"IRCCS Ospedale San Raffaele",{"name":59,"class":60},"Policlinico di Bari Giovanni XXIII","UNKNOWN",{"name":62,"class":6},"Azienda Ospedaliero Universitaria Policlinico Modena",{"name":64,"class":6},"Azienda Ospedaliero-Universitaria di Parma",{"name":66,"class":6},"Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna",{"name":68,"class":6},"Azienda Ospedaliera Sant'Anna",{"name":70,"class":60},"University Hospital Perugia",{"name":72,"class":6},"University of L'Aquila",{"name":74,"class":60},"Clinica Pediatrica Università di Novara",{"name":76,"class":60},"Santobono-Pausilpon Hospital",{"name":78,"class":60},"Policlinico G . Martino, Messina Italy",{"name":80,"class":6},"IRCCS Azienda Ospedaliero-Universitaria di Bologna",{"name":82,"class":60},"University Hospital of Ancona","100602656","metabolic-risk-assessment-in-prepubertal-children-with-congenital-hypothyroidism-100602656",false,"NCT07126353","Metabolic Risk Assessment in Prepubertal Children With Congenital Hypothyroidism","Metabolic Risk Assessment in Prepubertal Children With Congenital Hypothyroidism (IpoMet)","IpoMet","Inclusion Criteria:\n\n* Pubertal stage Tanner 1\n* Permanent congenital hypothyroidism\n* All ethnic groups\n* Informed consent signature\n\nExclusion Criteria:\n\n* Age\\\u003C 5 years\n* Pubertal stage Tanner 2-5\n* Transient congenital hypothyroidism or other type of hypothyroidism",true,"ALL","5 Years","12 Years",{"count":96,"type":97},170,"ESTIMATED","12 Months","OBSERVATIONAL","We propose a multicenter prospective study to define the prevalence and severity score of metabolic syndrome in a prepubertal pediatric cohort with congenital hypothyroidism, compared to a healthy and normal-weight pediatric population. These data will help to define whether hypothyroidism can be considered a risk factor for the metabolic health of the pediatric population. The possible identification of an at-risk metabolic profile will provide useful information to optimize the diagnostic and monitoring pathway for affected children.",[102,103],"Congenital Hypothyroidism","Metabolic Syndrome",[105,106,107],"Congenital hypothyroidism","metabolic syndrome","Obesity","NOT_YET_RECRUITING","2025-08-10",{"date":111,"type":112},"2025-08-17","ACTUAL",{"date":114,"type":97},"2025-09",{"date":116,"type":97},"2026-10",{"name":5,"class":6},1]