[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628474":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":31,"collaborators":10,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":10,"eligibilityCriteria":41,"healthyVolunteers":37,"sex":42,"minAge":43,"maxAge":44,"enrollmentInfo":45,"targetDuration":48,"studyType":49,"phases":10,"briefSummary":50,"conditions":51,"keywords":55,"overallStatus":60,"whyStopped":10,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Recep Tayyip Erdogan University Training and Research Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients diagnosed with metabolic syndrome",null,"Metabolic syndrome is diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP\u002FATP III) criteria. Diagnosis is made by meeting three of the following five criteria: waist circumference: ≥ 94 cm in men and ≥ 88 cm in women, blood pressure ≥ 130\u002F85 mmHg or use of antihypertensive medication, fasting blood glucose ≥ 100 mg\u002FdL or diagnosed type 2 diabetes, triglycerides ≥ 1.7 mmol\u002FL, and HDL \\\u003C 1.29 mmol\u002FL.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Oguz KOSE, Professor Dr.","CONTACT","+90 541 348 64 65","oguz.kose@erdogan.edu.tr",[19],{"facility":20,"status":10,"city":21,"state":22,"zip":23,"country":24,"countryCode":10,"cosmosGeoPoint":25,"geoPoint":30,"contacts":10},"Department of Periodontology of the Faculty of Dentistry of Recep Tayyip Erdogan University","Rize","Rize Province","53200","Turkey (Türkiye)",{"type":26,"coordinates":27},"Point",[28,29],40.52194,41.02083,{"lat":29,"lon":28},{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dilek KARADOĞAN","Assoc. Prof. Dr.","100628474","metabolic-syndrome-associated-diet-100628474",false,"NCT07462104","Metabolic Syndrome Associated Diet","Pro-İnflammatory Diet as a Modifying Factor in Periodontal Tissue Destruction Associated With Metabolic Syndrome","Inclusion Criteria:\n\n* Being between 18 and 65 years of age\n* Presence of at least three of the following parameters: (For MetS diagnosis) Waist circumference: ≥ 94 cm for men, ≥ 88 cm for women Blood pressure ≥ 130\u002F85 mmHg or taking antihypertensive medication Fasting blood glucose ≥ 100 mg\u002Fdl or diagnosed with Type 2 Diabetes Triglycerides ≥ 1.7 mmol\u002FL HDL \\\u003C 1.29 mmol\u002FL\n* Having at least 20 teeth\n* Not having received periodontal therapy in the last 6 months\n* Not having taken antibiotics, steroids, and\u002For nonsteroidal anti-inflammatory drugs in the last 3 weeks\n* Not having any autoimmune disease, osteoporosis, or cancer\n* Not taking immunosuppressive medications, oral contraceptives, Not taking bisphosphonates\n* Not being pregnant\n* Not having an active infectious disease (acute hepatitis, tuberculosis, AIDS)\n* Not taking chronic medications that affect periodontal tissues (cyclosporine A, phenytoin)\n* Not taking antioxidant supplements in the last 6 months\n\nExclusion Criteria:\n\n* Patients with an active infectious disease,\n* Those taking medications that could affect periodontal tissues,\n* History of endocarditis,\n* Recent antibiotic use (within 4 months),\n* Alcohol\u002Fdrug use,\n* Psychological disorders,\n* Eating disorders,\n* Dementia,\n* Pregnancy and breastfeeding,\n* Patients who did not sign the informed consent form","ALL","18 Years","65 Years",{"count":46,"type":47},100,"ESTIMATED","1 Day","OBSERVATIONAL","The goal of this observational study is to examine the relationship between metabolic syndrome (MetS) and periodontitis, and to evaluate the role of the Dietary Inflammatory Index (DII) in this association.\n\nThe main question it aims to answer is:\n\nDoes a pro-inflammatory diet, as measured by the DII, increase the risk or severity of periodontitis in individuals with metabolic syndrome?\n\nParticipants will include adults who meet the diagnostic criteria for metabolic syndrome. Their periodontal health will be assessed through standard clinical parameters, and dietary data will be collected using a validated food frequency questionnaire to calculate individual DII scores. The study will observe and analyze these factors to explore potential links between diet-induced inflammation, systemic metabolic health, and periodontal outcomes.",[52,53,54],"Metabolic Syndrome (MetS)","Periodontitis","Diet, Food and Nutrition",[56,57,58,59],"metabolic syndrome","periodontitis","diet","inflammation","NOT_YET_RECRUITING","2026-03-04",{"date":63,"type":64},"2026-03-10","ACTUAL",{"date":66,"type":47},"2026-03-23",{"date":68,"type":47},"2026-11-23",{"name":5,"class":6},1]