[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607251":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":27,"locations":35,"responsibleParty":51,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":10,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Bagcilar Training and Research Hospital","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"group 1 and group 2",null,"Group 1 with indication for MTX treatment and group 2 with relative indication for MTX treatment",[13],"Drug: Drug: Methotrexate (MTX) Patients received methotrexate treatment according to institutional protocols. Dosage and administration routes were recorded retrospectively. For patients who did not respond",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Drug: Methotrexate (MTX) Patients received methotrexate treatment according to institutional protocols. Dosage and administration routes were recorded retrospectively. For patients who did not respond","MTX medical treatment Laparoscopic salpingectomy Laparoscopic salpingostomy",[9],[21],"surgical treatment",[23],{"name":24,"affiliation":25,"role":26},"gülhan özüm, md","Sağlık Bilimleri Üniversitesi, Bağcılar Eğitim ve Araştırma Hastanesi","PRINCIPAL_INVESTIGATOR",[28,32],{"name":24,"role":29,"phone":30,"phoneExt":10,"email":31},"CONTACT","+905355784928","gulhanozum86@gmail.com",{"name":33,"role":29,"phone":34,"phoneExt":10,"email":31},"gülhan özüm","05355784928",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":10,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"University of Health Sciences, Training and Research Hospital","RECRUITING","Istanbul","Türkiye","34200","Turkey (Türkiye)",{"type":44,"coordinates":45},"Point",[46,47],28.94966,41.01384,{"lat":47,"lon":46},[50],{"name":33,"role":29,"phone":34,"phoneExt":10,"email":31},{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100607251","methotrexate-treatment-in-cases-of-ectopic-pregnancy-with-relative-contraindications-100607251",false,"NCT07186127","Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications","A Retrospective Evaluation of the Effectiveness of Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications","Inclusion Criteria:\n\n* Diagnosed with ectopic pregnancy\n* Received methotrexate (MTX) treatment\n* Underwent surgical treatment due to lack of response to MTX therapy\n* Compliant with treatment follow-up\n\nExclusion Criteria:\n\n* Participants with contraindications to methotrexate (MTX) treatment\n* Participants non-compliant with follow-up","FEMALE","18 Years","48 Years",{"count":64,"type":65},230,"ESTIMATED","OBSERVATIONAL","Study Description (For Patients, Families, and Healthcare Providers)\n\nPurpose:\n\nThe aim of this study is to evaluate the effectiveness and safety of methotrexate treatment in women with ectopic pregnancy who belong to a group for whom this treatment is relatively contraindicated.\n\nBackground:\n\nMethotrexate is a medication commonly used in the treatment of ectopic pregnancy (a pregnancy that occurs outside the uterus, usually in the fallopian tube). However, in certain conditions - such as kidney or liver dysfunction - methotrexate use may carry increased risks. These situations are known as relative contraindications. This study will retrospectively examine treatment outcomes in this specific patient population.\n\nMethod:\n\nThe study will analyze medical records of patients who were previously treated with methotrexate for ectopic pregnancy. No new interventions will be performed. The analysis will be based solely on existing clinical data.\n\nWhy Is This Important? The findings of this study may help us better understand the safety limits of methotrexate therapy and guide healthcare providers in managing similar cases in the future.",[69],"Ectopic Pregnancy",[69,71,72,73],"Relative Contraindication","Methotrexate","Laparoscopic surgery","2025-09-15",{"date":76,"type":77},"2025-09-22","ACTUAL",{"date":79,"type":77},"2025-05-01",{"date":81,"type":65},"2026-05-01",{"name":5,"class":6},1]