[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571429":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":44,"responsibleParty":60,"collaborators":64,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":10,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":10,"enrollmentInfo":77,"targetDuration":10,"studyType":80,"phases":10,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":46,"whyStopped":10,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,14,17],{"label":9,"type":10,"description":11,"interventionNames":12},"Bone void following bone tumor resection",null,"Patients are being targeted because they have already agreed to receive OSTEOCRETE as part of standard clinical care. They will complete surveys, blood draws to test for magnesium levels, and low-dose CT scans at various post-operative timepoints.",[13],"Device: Mg OSTEOCRETE as a bone void filler",{"label":15,"type":10,"description":11,"interventionNames":16},"Bone defect caused by aseptic loosening of orthopaedic implants",[13],{"label":18,"type":10,"description":11,"interventionNames":19},"Bone defect caused by trauma-related condition",[13],[21,26,29],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"DEVICE","Mg OSTEOCRETE as a bone void filler","Patients will be treated with Mg OSTEOCRETE as per standard clinical care to fill defects in bone left by bone tumor resection",[9],{"type":22,"name":23,"description":27,"armGroupLabels":28,"otherNames":10},"Patients will be treated with Mg OSTEOCRETE as per standard clinical care to fill defects in bone left by aseptic loosening of orthopaedic hardware",[15],{"type":22,"name":23,"description":30,"armGroupLabels":31,"otherNames":10},"Patients will be treated with Mg OSTEOCRETE as per standard clinical care to fill defects in bone left by trauma-related conditions",[18],[33],{"name":34,"affiliation":5,"role":35},"Santiago A Lozano-Calderon, MD, PhD","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":10,"email":41},"Shreya Halur, BS","CONTACT","617-726-4932","shalur@mgh.harvard.edu",{"name":34,"role":39,"phone":43,"phoneExt":10,"email":10},"617-643-4947",[45],{"facility":5,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Boston","Massachusetts","02114","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-71.05977,42.35843,{"lat":56,"lon":55},[59],{"name":38,"role":39,"phone":40,"phoneExt":10,"email":41},{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Santiago Lozano-Calderon","Attending Orthopaedic Surgeon\u002FAssistant Professor",[65],{"name":66,"class":67},"Bone Solutions Inc","UNKNOWN","100571429","mg-osteocrete-post-treatment-outcomes-100571429",false,"NCT06720142","Mg OSTEOCRETE Post-Treatment Outcomes","Clinical and Radiographic Outcomes of Patients Treated With Mg OSTEOCRETE","Inclusion Criteria:\n\n* 18 years of age and older on the day of surgery\n* has received or will receive Mg OSTEOCRETE as a component of their treatment at this institution in accordance with Instructions for Use for the implanted product\n* Mg OSTEOCRETE is indicated for one of the following reasons:\n\n  1. as a bone void filler following bone tumor resection, or;\n  2. as an augment for defects causing aseptic loosening of orthopaedic implants, or;\n  3. to help substitute bone for trauma-related conditions\n\nExclusion Criteria:\n\n* any contraindication as per Instructions for Use for Mg OSTEOCRETE","ALL","18 Years",{"count":78,"type":79},10,"ESTIMATED","OBSERVATIONAL","Mg OSTEOCRETE is a bone substitute used to fill a defect in bone caused by excision of a tumor, orthopaedic hardware that has become loosened, or a trauma-related condition. The aim of this study is to determine the amount of time it takes for bone to heal after treatment with Mg OSTEOCRETE, and to better understand the efficacy of this treatment through clinical and patient-reported outcomes.",[83,84,85],"Cancer of Bone","Trauma","Aseptic Loosening of Orthopaedic Hardware",[87,88,89],"bone defect","bone substitute","osteocrete","2026-04-21",{"date":92,"type":93},"2026-04-22","ACTUAL",{"date":95,"type":93},"2025-03-17",{"date":97,"type":79},"2028-03-17",{"name":62,"class":6},1]