[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596153":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":41,"centralContacts":47,"locations":31,"responsibleParty":57,"collaborators":31,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":31,"enrollmentInfo":71,"targetDuration":31,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":31,"overallStatus":80,"whyStopped":31,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":31},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A","PLACEBO_COMPARATOR","(n=20); will be treated with combination of microneedling with saline.",[13],"Device: Microneedling alone",{"label":15,"type":16,"description":17,"interventionNames":18},"Group B","ACTIVE_COMPARATOR","(n=20);will be treated with combination of microneedling and topical bleomycin.",[19,13],"Drug: Bleomycin",{"label":21,"type":16,"description":22,"interventionNames":23},"Group c","(n=20);will be treated with combination of microneedling and topical 5-flurouracil .",[13,24],"Drug: 5 fluorouracil",[26,32,37],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","Bleomycin",");will be treated with combination of microneedling and topical bleomycin .",[15],null,{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":31},"DEVICE","Microneedling alone","' Microneedling will be performed on each wart using dermapen supplied with 12 needles arranged in rows. Topical anesthetic cream will be applied for 60 min before the procedures. Microneedling will be performed on each wart using dermapen. The penetration depth will be adjusted at 2-mm, endpoint is pinpoint bleeding and the dermapen will be held by the hand in a vertical direction on the warts.",[9,15,21],{"type":27,"name":38,"description":39,"armGroupLabels":40,"otherNames":31},"5 fluorouracil",");will be treated with combination of microneedling and topical 5-flurouracil .",[21],[42,45],{"name":43,"affiliation":5,"role":44},"Rofaida Refaat Shehata, Assistant professor","STUDY_DIRECTOR",{"name":46,"affiliation":5,"role":44},"Amira ali abdelmotaleb, professor",[48,53],{"name":49,"role":50,"phone":51,"phoneExt":31,"email":52},"aya magdi mohamed, resident doctor","CONTACT","01023856887","ayamagdi349@gmail.com",{"name":54,"role":50,"phone":55,"phoneExt":31,"email":56},"Amira Ali Abdelmotaleb, Professor","01005263721","amiraali21@aun.edu.eg",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Aya magdi mohamed mahmoud","resident doctor at Dermatology, Venereology and Andrology department","100596153","microneedling-alone-versus-microneedling-coupled-with-either-bleomycin-or-5flourouracil-in-the-treatment-of-plantar-warts-100596153",false,"NCT07041749","Microneedling Alone Versus Microneedling Coupled With Either Bleomycin or 5flourouracil in the Treatment of Plantar Warts","Comparison of the Efficacy of Microneedling Alone Versus Microneedling Coupled With Either Bleomycin or 5flourouracil in the Treatment of Plantar Warts","plantar warts","Inclusion Criteria:\n\n\\-\n\nExclusion Criteria:\n\n\\- 1. Children below 18. 2.Pregnant and lactating women. 3.Patients with any systemic disease or immunocompromised Patients or patients receiving any immunosuppressive drugs.\n\n4\\. Impaired wound healing or imunosuppresion. 5.Patients who received any treatment for warts in the last month before study.","ALL","18 Years",{"count":72,"type":73},60,"ESTIMATED","INTERVENTIONAL",[76],"NA","To compare between the efficacy and safety of microneedling alone, microneedling with topical bleomycin and microneedling with 5-flurouracil in treatment of planter warts.\n\nMicroneedling will be performed on each wart using dermapen supplied with 12 needles arranged in rows. Topical anesthetic cream will be applied for 60 min before the procedures. Microneedling will be performed on each wart using dermapen. The penetration depth will be adjusted at 2-mm, endpoint is pinpoint bleeding and the dermapen will be held by the hand in a vertical direction on the warts.\n\nBleomycin is typically supplied in 15 U vials. The preparation will be diluted first with 7 mL normal saline ,double the amount taken from the vial by adding the same amount lidocaine (2%), so that the concentrations become 1 U\u002FmL . The maximum total amount of bleomycin taken to each patient in one session will be 1 U\u002F1 mL . Microneedling will be performed on the lesion using a microneedling pen type device with a 1-cm tip diameter at a 2-mm depth setting for 2-3 minutes until pinpoint bleebing occurs 1 mL of the prepared solution of bleomycin (1 U\u002F1 mL) will be dropped on to the wart tissue using insulin syringe and occlusion will be applied for 3 hours.\n\n5-FU is available in 10 mL vial: 500 mg\u002F10 mL. Application of 5-FU solution will be done by dropping using an insulin syringe (1 mL)to help dropping of the solution on the warts surface. Then, the lesion will be occluded with a plaster for 3 h.\n\nSessions: Sessions will be performed every 2 weeks until complete cure or for maximum 6 sessions (total 3 month)",[79],"Warts of Foot","NOT_YET_RECRUITING","2025-06-26",{"date":83,"type":84},"2025-06-27","ACTUAL",{"date":86,"type":73},"2026-06-01",{"date":88,"type":73},"2027-07-01",{"name":5,"class":6}]