[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100517725":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":25,"locations":31,"responsibleParty":47,"collaborators":11,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":11,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":11,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":34,"whyStopped":11,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Alexandria University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Microneedling with topical application of regular insulin","ACTIVE_COMPARATOR",null,[13],"Other: Microneedling with topical application of regular insulin",{"label":15,"type":10,"description":11,"interventionNames":16},"Microneedling only",[17],"Other: Microneedling with topical application of saline",[19,22],{"type":6,"name":9,"description":20,"armGroupLabels":21,"otherNames":11},"Microneeling preformed onto the scar In one group insulin will be applied while saline will be used in the second group",[9],{"type":6,"name":23,"description":20,"armGroupLabels":24,"otherNames":11},"Microneedling with topical application of saline",[15],[26],{"name":27,"role":28,"phone":29,"phoneExt":11,"email":30},"Dalia I Halwag, PhD, MD","CONTACT","+00201224489473","daliahalwag@gmail.com",[32],{"facility":33,"status":34,"city":35,"state":11,"zip":11,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Alexandria University, Faculty of Medicine","RECRUITING","Alexandria","Egypt","EG",{"type":39,"coordinates":40},"Point",[41,42],29.91582,31.20176,{"lat":42,"lon":41},[45],{"name":27,"role":28,"phone":46,"phoneExt":11,"email":30},"+0201224489473",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Dalia Ibrahim Halwag","Lecturer and Consultant of Dermatology, Venereology and Andrology, Faculty of Medicine","100517725","microneedling-with-regular-insulin-versus-microneedling-alone-in-treatment-of-atrophic-scars-100517725",false,"NCT06021275","Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars","Inclusion Criteria:\n\n1. Patients aged 12 to 60 years\n2. Atrophic scars (traumatic or surgical)\n3. Completely healed scars\n\nExclusion Criteria:\n\n1. Patients with a tendency or history of hypertrophic or keloidal scars\n2. Patients who received treatment for their scar in the past 3 months\n3. Diabetic patients or those with a history of Dysglycemia\n4. Pregnant, or lactating females\n5. Patients with active infection at the site of scar\n6. Patients currently receiving isotretinoin treatment or in the past month","ALL","12 Years","60 Years",{"count":61,"type":62},40,"ESTIMATED","INTERVENTIONAL",[65],"NA","Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars. In addition, a lack of inclusion of a control group instead of comparing topical preparations with insulin was also a limitation to these studies. A control group consisting of microneedling alone would have served as a better comparison in order to determine whether the effects of microneedling are augmented by topical protein-rich preparations.",[68,69],"Scars","Insulin",[69,71],"scars","2024-07-27",{"date":74,"type":75},"2024-07-30","ACTUAL",{"date":77,"type":75},"2023-10-01",{"date":79,"type":62},"2024-12",{"name":5,"class":6},1]