[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100484687":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":29,"locations":35,"responsibleParty":65,"collaborators":67,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":84,"studyType":85,"phases":10,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Azienda Ospedaliero Universitaria Maggiore della Carita","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients",null,"Patients with acute CO poisoning needing a hyperbaric oxygen treatment",[13],"Diagnostic Test: Microparticles research",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy controls","Healthy controls i.e., healthy phisicians than will enter the hyperbaric oxygen therapy chamber to assist the patients",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","Microparticles research","The absolute count of the total circulating microparticles will be carried out on the patients' plasma using the NanoSight NS300 instrument (Alphatest). Furthermore, the circulating microparticles will be stained with a combination of three monoclonal antibodies (Becton and Dickinson, NJ,USA) to detect microparticles released by the most abundant cell populations in the blood: leukocyte-derived microparticles (CD45+), endothelial-derived microparticles (CD31+), and PLT-derived microparticles (CD31+ CD41a+).",[15,9],[25],{"name":26,"affiliation":27,"role":28},"Rosanna Vaschetto, MD, PhD","University of Eastern Piedmont","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Rosanna Vaschetto","CONTACT","+39 3342724811","rosanna.vaschetto@med.uniupo.it",[36],{"facility":37,"status":38,"city":39,"state":10,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"AOU Maggiore della Carità","RECRUITING","Novara","28100","Italy","IT",{"type":44,"coordinates":45},"Point",[46,47],8.62118,45.44694,{"lat":47,"lon":46},[50,52,55,57,59,61,63],{"name":31,"role":32,"phone":51,"phoneExt":10,"email":34},"3342724811",{"name":53,"role":54,"phone":10,"phoneExt":10,"email":10},"Carlo Olivieri, MD","SUB_INVESTIGATOR",{"name":56,"role":54,"phone":10,"phoneExt":10,"email":10},"Andrea Giovanniello, MD",{"name":58,"role":54,"phone":10,"phoneExt":10,"email":10},"Davide Colombo, MD",{"name":60,"role":54,"phone":10,"phoneExt":10,"email":10},"Racca Fabrizio, MD",{"name":62,"role":54,"phone":10,"phoneExt":10,"email":10},"Puggioni Angelo, MD",{"name":64,"role":54,"phone":10,"phoneExt":10,"email":10},"Zorzi Stefano, MD",{"type":28,"investigatorFullName":26,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Professor",[68],{"name":69,"class":6},"Università degli Studi del Piemonte Orientale Amedeo Avogadro","100484687","microparticles-blood-level-in-acute-carbon-monoxide-poisoning-100484687",false,"NCT05591300","Microparticles Blood Level in Acute Carbon Monoxide Poisoning","COMPs","Inclusion Criteria:\n\n* Age \\> 18 years\n* Acute carbon monoxide poisoning\n* Need for treatment with hyperbaric oxygen\n\nExclusion Criteria:\n\n* Patient reject to consent",true,"ALL","18 Years","99 Years",{"count":82,"type":83},108,"ESTIMATED","45 Days","OBSERVATIONAL","The goal of this pilot, clinical, experimental, biological and prospective study with uso of biological material (venous blood sampling), in patient with acute carbon monoxide (CO) intoxication and in a group of healthy non-intoxicated subject (group of control) is the research of a possible increase of circulating microparticles level in human blood with an acute carbon monoxide intoxication.\n\nThe main question to answer is:\n\nIs there an increase of circulating microparticles levels in subjects with acute carbon monoxide poisoning? Two blood samples will be withdrawn from patients with acute carbon monoxide poisoning, one before and one after hyperbaric oxygen treatment.\n\nResearchers will compare a group of healthy volunteers to see if there is a different in circulating microparticles blood level compared to patients with intoxication.",[88],"Carbon Monoxide Poisoning",[90,91,92,93,94,95,96],"Carbon monoxide intoxication","Microparticles","Microvesicles","Carbon monoxide poisoning","CO","Delayed neurological syndrome","Hyperbaric Oxygen","2024-11-13",{"date":99,"type":100},"2024-11-14","ACTUAL",{"date":102,"type":100},"2022-11-15",{"date":104,"type":83},"2025-11",{"name":5,"class":6},1]