[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100371623":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":32,"centralContacts":36,"locations":46,"responsibleParty":75,"collaborators":78,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":10,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":88,"minAge":89,"maxAge":10,"enrollmentInfo":90,"targetDuration":10,"studyType":93,"phases":10,"briefSummary":94,"conditions":95,"keywords":99,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"Danish Research Centre for Magnetic Resonance","OTHER",[8,15,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Minor Stroke patients",null,"* Clinical Assessment\n* MRI scan session",[13,14],"Other: Clinical Assessment","Procedure: MRI scan",{"label":16,"type":10,"description":11,"interventionNames":17},"TIA patients",[13,14],{"label":19,"type":10,"description":20,"interventionNames":21},"Healthy Controls","* MRI scan session",[14],[23,27],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Clinical Assessment","1. Medical history and details of the vascular incident will be collected from the patient and the medical journal. (Duration: 1hr)\n2. Neuropsychological measures collected using test measures and questionaries (duration approx 45-60 min).",[9,16],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"PROCEDURE","MRI scan","1\\. MRI scan session, which includes Structural, Quantitative, Functional and Diffusion MRI sequences. (maximum duration: 90 min).",[19,9,16],[33],{"name":34,"affiliation":5,"role":35},"Tim B. Dyrby, Professor","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":10,"email":41},"Maria del Carmen Moreno Genis, MSc","CONTACT","38626446","carmenmg@drcmr.dk",{"name":43,"role":39,"phone":44,"phoneExt":10,"email":45},"Tim Bjørn Dyrby, Professor","38626542","timd@drcmr.dk",[47,67],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Bispebjerg Hospital","RECRUITING","Copenhagen","København NV","2400","Denmark","DK",{"type":56,"coordinates":57},"Point",[58,59],12.56553,55.67594,{"lat":59,"lon":58},[62,66],{"name":63,"role":39,"phone":64,"phoneExt":10,"email":65},"Hanne Christensen, MD","38635070","hanne.krarup.christensen@regionh.dk",{"name":63,"role":35,"phone":10,"phoneExt":10,"email":10},{"facility":5,"status":49,"city":50,"state":10,"zip":68,"country":53,"countryCode":54,"cosmosGeoPoint":69,"geoPoint":71,"contacts":72},"2650",{"type":56,"coordinates":70},[58,59],{"lat":59,"lon":58},[73,74],{"name":34,"role":39,"phone":44,"phoneExt":10,"email":45},{"name":38,"role":39,"phone":40,"phoneExt":10,"email":41},{"type":35,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Tim Dyrby","Senior Researcher",[79],{"name":48,"class":6},"100371623","microstructure-imaging-in-stroke-patients-100371623",false,"NCT04118790","Microstructure Imaging in Stroke Patients","New Clinical Magnetic Resonance Technologies for Capturing Brain Microstructure Alterations in Patients With Minor Stroke or Transient Ischemic Attack","Patient Inclusion Criteria:\n\n* Stroke or TIA (ABCD2\\>4 and\u002For acute Diffusion-Weighted Image (DWI) lesion).\n* Modified Rankin Scale \\\u003C=2.\n* As perceived by the investigator, have the ability to comply with all requirements of the study protocol.\n* Have the ability to understand and sign the Informed Consents Form.\n* Multidimensional Fatigue Inventory score \\>= 12 on general fatigue.\n\nPatient Exclusion Criteria:\n\n* The DRCMR´s general exclusion criteria for MRI research.\n* Pregnancy or lactation; human chorionic gonadotropin (hCG) urine test is offered for women \\\u003C 55 years.\n* Major medical illness (for instance: anemia, diabetes mellitus, thyroid disorders, cardiovascular disease, electrolyte imbalance, etc.)\n* Treated with ritalin or modafinil.\n* Known uncontrolled severe malignancy.\n* Known drug or alcohol addiction.\n* Tiredness due to pharmaceutical side effects, as identified by the Investigator.\n* Max body weight of 130 kg.\n* Persons who do not wish to be informed about abnormal findings as part of the investigations.\n\nHealthy Controls Exclusion Criteria:\n\n* The DRCMR´s general exclusion criteria for MRI research.\n* Pregnancy or lactation; urin hCG test is offered for women \\\u003C 55 years.\n* Major medical illness (for instance: anemia, diabetes mellitus, thyroid disorders, cardiovascular disease, electrolyte imbalance, etc.)\n* Anamnestic infection (cystitis, influenza, pneumonia, etc) the last 3 weeks.\n* Known malignancy.\n* Known drug or alcohol addiction.\n* Tiredness due to pharmaceutical side effects.\n* Max body weight of 130 kg.\n* Persons who do not wish to be informed about abnormal findings as part of the investigations.\n\nHealthy Controls Inclusion Criteria:\n\n* Healthy\n* Age- and sex-matched to patient groups.\n* As perceived by the investigator, have the ability to comply with all requirements of the study protocol.\n* Have the ability to understand and sign the Informed Consents Form.",true,"ALL","18 Years",{"count":91,"type":92},90,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to establish a methodological framework based on existing advanced neuroimaging technologies as a new clinical neuroimaging tool for assessment of possible affected brain connections in stroke and TIA patients. Thus, providing new insights into microstructural changes that may underline why those patients experience deficits like fatigue.",[96,97,98],"Fatigue","Stroke, Acute","Transient Ischemic Attack",[96,100,101,102,103,104,105,106,107,108,109],"minor stroke","TIA","Diffusion","MRI","Quantitative","Sequence","Microstructure","Axon","Myelin","Degeneration","2022-05-25",{"date":112,"type":113},"2022-05-26","ACTUAL",{"date":115,"type":113},"2019-12-23",{"date":117,"type":92},"2029-03-01",{"name":5,"class":6},2]