[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100403136":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":29,"collaborators":11,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":11,"eligibilityCriteria":39,"healthyVolunteers":35,"sex":40,"minAge":41,"maxAge":42,"enrollmentInfo":43,"targetDuration":11,"studyType":46,"phases":47,"briefSummary":49,"conditions":50,"keywords":11,"overallStatus":52,"whyStopped":11,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":11},{"fullName":5,"class":6},"Jewish General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Prominent middle lobe BPH satisfactory channel after MLO PVP","EXPERIMENTAL",null,[13],"Procedure: Middle lobe only Photoselective vaporization of the prostate (PVP)",{"label":15,"type":16,"description":11,"interventionNames":17},"Prominent middle lobe BPH unsatisfactory channel after MLO PVP","ACTIVE_COMPARATOR",[18],"Procedure: Complete PVP",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"PROCEDURE","Middle lobe only Photoselective vaporization of the prostate (PVP)","Middle lobe only Photoselective vaporization of the prostate (PVP) without vaporization of the lateral lobes",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Complete PVP","Traditional Photoselective vaporization of the prostate PVP",[15],{"type":30,"investigatorFullName":31,"investigatorTitle":32,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Jacques Corcos","Professor of Surgery (Urology)","100403136","middle-lobe-only-laser-vaporization-or-total-prostate-vaporization-of-the-prostate-prospective-cohort-study-100403136",false,"NCT04529369","Middle Lobe Only Laser Vaporization or Total Prostate Vaporization of the Prostate, Prospective Cohort Study","Efficacy and Long-term Durability of Middle Lobe Only (MLO) Versus Complete Trans-Urethral Vaporization of the Prostate (PVP), Prospective Cohort Study.","Inclusion Criteria:\n\n* Adult males (18-year-old and more)\n* Suffering bothersome LUTS or urinary retention secondary to BPH\n* Cystoscopic examination documenting the predominant middle lobe prostatic adenoma that is considered to be the primary cause of BOO.\n\nExclusion Criteria:\n\n* Patients neurogenic lower urinary tract dysfunction (Neurogenic Bladder)\n* Not competent to give consent and\u002For inability to provide answers to the questionnaire\n* Patient who refuse to participate in the study\n* Patients without a median lobe\n* Patients who have a large prostate (more than 120 g on trans-abdominal ultrasound prostate sizing).\n* Patients who have renal impairment secondary to BPH\n* Patients with proven or suspicion of prostate cancer based on clinical examination and\u002For PSA level\n* Patients with refractory hematuria secondary to BPH\n* Patients with urethral strictures\n* Patients with bladder cancer\n* Patients with history of pelvic radiotherapy","MALE","18 Years","100 Years",{"count":44,"type":45},280,"ESTIMATED","INTERVENTIONAL",[48],"NA","The investigator aims to prospectively investigate the efficacy and durability of the middle lobe only versus traditional complete photoselective greenlight vaporization of the prostate in patients with prominent middle lobe. The investigator will select patients based on pre-op cystoscopy if patients have a prominent middle lobe to participate in this study. Researches will start to vaporize only the middle lobe then, at the end of this step, The investigator will look at the verumontanum into the prostatic fossa and determine if the patient is having adequate opened prostatic fossa or not. Patients with unsatisfactory opened fossa will have a complete PVP of lateral lobes, while patients with a satisfactory channel will not receive a complete PVP. Primary objectives of the study are to look into pre and post-operative uroflowmetry and post-void residual, International prostate symptoms scores, need of catheterization, and need for secondary interventions over five then ten years. Secondary objectives are to look into erectile and ejaculatory status using the Male Sexual Health Questionnaire (MSHQ) and MSHQ-EjD Short Form for Assessing EjD. Researchers will follow the patients at three months, six months, one year then yearly for five years then an extension to up to 10 years.",[51],"Benign Prostatic Hyperplasia","NOT_YET_RECRUITING","2020-08-25",{"date":55,"type":56},"2020-08-27","ACTUAL",{"date":58,"type":45},"2020-10",{"date":60,"type":45},"2030-10",{"name":5,"class":6}]