[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567141":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":62,"collaborators":12,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":12,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":12,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":91,"whyStopped":12,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Konkuk University Medical Center","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","NO_INTERVENTION","patients undergoing cardiac surgery supposed not to get aucte normovolemic hemodilution (ANH) before CPB",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Acute normovolemic hemodilution group","ACTIVE_COMPARATOR","patients undergoing cardiac surgery supposed to get aucte normovolemic hemodilution (ANH) before CPB",[18,19],"Procedure: Acute normovolemic hemodilution (ANH)","Drug: hydroxyethyl starch (HES 130\u002F0.6)",[21,26],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":12},"PROCEDURE","Acute normovolemic hemodilution (ANH)","applying acute normovolemic hemodilution (ANH) by using HES 130\u002F0.4 of 5 ml\u002Fkg before the initiation of cardiopulmonary bypass",[14],{"type":27,"name":28,"description":28,"armGroupLabels":29,"otherNames":12},"DRUG","hydroxyethyl starch (HES 130\u002F0.6)",[14],[31],{"name":32,"affiliation":5,"role":33},"Tae-Yop Kim, MD, PhD","PRINCIPAL_INVESTIGATOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":12,"email":38},"CONTACT","+82-2-2030-5445","taeyop@gmail.com",{"name":40,"role":36,"phone":41,"phoneExt":12,"email":42},"Wooseul Lee, Bachelor","+82-2-2030-5448","wslee.kku@gmail.com",[44,54],{"facility":5,"status":12,"city":45,"state":45,"zip":46,"country":47,"countryCode":12,"cosmosGeoPoint":48,"geoPoint":53,"contacts":12},"Seoul","05030","South Korea",{"type":49,"coordinates":50},"Point",[51,52],126.9784,37.566,{"lat":52,"lon":51},{"facility":5,"status":12,"city":45,"state":12,"zip":55,"country":47,"countryCode":12,"cosmosGeoPoint":56,"geoPoint":58,"contacts":59},"143-729",{"type":49,"coordinates":57},[51,52],{"lat":52,"lon":51},[60],{"name":61,"role":36,"phone":37,"phoneExt":12,"email":38},"Tae-Yop Kim, MD PhD",{"type":33,"investigatorFullName":61,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Professor of Anesthesiology","100567141","mild-anh-on-pre-bypass-coagulation-function-during-cardiac-surgery-100567141",false,"NCT06664320","Mild ANH on Pre-bypass Coagulation Function During Cardiac Surgery","Impact of Mild Acute Normovolemic Hemodilution on Pre-bypass Coagulation Function During Cardiac Surgery","Inclusion Criteria:\n\n* patients undergoing cardiac surgery with cardiopulmonary bypass who signed written informed consent\n\nExclusion Criteria:\n\n* preoperative renal failure requiring reran replacement therapy\n* preoperative liver disease\n* preoperative low cardiac output (EF \\\u003C 50%)\n* Preoperative IABP application, Atrial fibrillation, Pacemaker\n* contraindication for applying TEE\n* intraoperative withdrawal","ALL","19 Years","65 Years",{"count":75,"type":76},70,"ESTIMATED","INTERVENTIONAL",[79],"NA","The impact of acute normovolemic hemodilution (ANH) using hydroxyethyl starch before initiating cardiopulmonary bypass (CPB) on whole blood viscoelastic profile after CPB has not been well established. Patients undergoing cardiac surgery employing moderate hypothermic CPB are randomly allocated into one of two groups: in Group-ANH, ANH is applied by using a balanced hydroxyethyl starch (HES 130\u002F0.6); and in Group-C, ANH is not applied. After weaning from CPB, intergroup differences of INTEM, EXTEM, FIBTEM, and APTEM profiles are analyzed. As a primary outcome, the inter-group differences between maximal clot firmness of EXTEM will be determined at 10 min after ANH in Group-ANH and that at control.",[82,83,84],"Mitral Regurgitation","Mitral Stenosis","Tricuspid Regurgitation",[86,87,88,89,90],"rotational thromboelastometry","cardiac surgery","acute normovolemic hemodilution","hemodilution","coagulation","NOT_YET_RECRUITING","2024-10-30",{"date":94,"type":95},"2024-10-31","ACTUAL",{"date":97,"type":76},"2024-10-28",{"date":99,"type":76},"2025-04-30",{"name":5,"class":6},2]