[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100527811":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":57,"collaborators":60,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":25,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":89,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Indiana University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Enhanced Usual Care (EUC)","ACTIVE_COMPARATOR","Participants randomized to EUC will have access to existing usual primary care services. They will also be enrolled in Hypertension Self-Management Education and Support (SMES) class (\"Hypertension group\"), which is an existing CDC-endorsed program offered at Eskenazi Health to provide information and skills for managing hypertension (HTN). Classes are led by registered dietitians via Webex.",[13],"Behavioral: Enhanced Usual Care (EUC)",{"label":15,"type":16,"description":17,"interventionNames":18},"Food Delivery and Cooking PLUS Aerobic Training (FoRKS+)","EXPERIMENTAL","Participants randomized to FoRKS+ will attend weekly HTN SMES classes separately from EUC participants. SMES classes will include the EUC curriculum stated above and an introduction to the upcoming FoRKS+ intervention.\n\nFollowing HTN SMES completion, FoRKS+ continues with home-delivered Mediterranean-style ingredient kits, food management lessons, and hands-on cooking classes in one's own kitchen. Classes are led by registered dietitians via Webex. Classes are held twice per week thru Week 12, then only once per week through Week 16. Intervention continues with aerobic exercise led by health coaches via Webex. Classes start in Week 13 with one session per week, increasing to two sessions per week in Weeks 17-28.",[19],"Behavioral: Food Delivery and Cooking PLUS Aerobic Training (FoRKS+)",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Enhanced Usual Care (EUC) includes 5 weeks of hypertension classes.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Food Delivery and Cooking PLUS Aerobic Training (FoRKS+) includes 5 weeks of hypertension classes followed by 11 weeks of home-delivered Mediterranean-style ingredient kits and virtual cooking classes, and an additional 12 weeks of aerobic exercise.",[15],[30],{"name":31,"affiliation":5,"role":32},"Daniel O Clark, PhD","PRINCIPAL_INVESTIGATOR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","317-274-9292","daniclar@iu.edu",{"name":39,"role":35,"phone":40,"phoneExt":25,"email":41},"Lyndsi R Moser, BA, CCRP","317-963-7301","lrhabegg@iupui.edu",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":25},"Eskenazi Health","RECRUITING","Indianapolis","Indiana","46202","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-86.15804,39.76838,{"lat":55,"lon":54},{"type":32,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Daniel Clark","Associate Professor of Medicine",[61,64],{"name":62,"class":63},"National Institutes of Health (NIH)","NIH",{"name":65,"class":63},"National Institute on Aging (NIA)","100527811","mind-foods-and-aerobic-training-in-black-adults-with-htn-100527811",false,"NCT06152614","MIND Foods and Aerobic Training in Black Adults With HTN","MIND Foods and Aerobic Training in Black Adults With HTN: An ADRD Prevention Pilot RCT","MAT","Inclusion Criteria:\n\n1. Fluent in English\n2. Marion County resident\n3. 35-75 years\n4. Self-identified non-Hispanic and Black\u002FAfrican-American\u002Fbiracial including African-American\n5. Systolic BP of ≥140 in prior 12 months from a primary care visit\n6. Ability to see and read street signs (self report)\n7. Stable housing with independent access to kitchen, including functional stove or hotplate, oven, refrigerator, and freezer (self report)\n8. Activity independence per functional activities questionnaire (FAQ; \\\u003C3 responses of \"Require Assistance\" and 0 responses of \"Dependent\")\n9. Normal cognition per six-item screener (SIS; score of ≥ 5)\n10. Less than 20min on usual day of moderate or vigorous physical activity\n11. Able to exercise safely per abbreviated Exercise Assessment for You (EASY) or primary care provider clearance\n12. Mean systolic BP of ≥130 from 3 standard BP measurements taken by research staff following standardized wait periods.\n\nExclusion Criteria:\n\n1. lives in nursing home\n2. diagnosis of dementia or Alzheimer disease or mild cognitive impairment; Parkinson disease; brain tumor\u002Finfection\u002Fsurgery (within the last 10 years with residual symptoms and\u002For functional loss\u002Fdeficit, such as impaired learning, memory, or communication); cancer with short life expectancy, or current chemotherapy or radiation therapy; psychosis, schizophrenia, or bipolar disorder\n3. ICD 10 code I11\u002Fhypertensive heart disease, ICD 10 code I12\u002Fhypertensive CKD, ICD 10 code I13\u002Fhypertensive heart disease and CKD, ICD 10 code I15, or ICD 10 code I16\n4. current or past prescription of donepezil, memantine, rivastigmine, or galantamine\n5. alcohol consumption ≥ 8 drinks per week for women, or ≥15 drinks per week for men\n6. drug use\u002Fabuse (excluding marijuana) per EMR\n7. moving out of area during study timeline\n8. scheduling conflicts with intervention schedule\n9. unwilling to use a touchscreen\n10. unwilling to be on video conferencing\n11. low communicative ability, functional status, or other disorders (examiner rated) that would interfere with interventions and assessments\n12. unable to provide informed consent\n13. participation in any lifestyle modification\u002Fweight loss program (e.g., Weight Watchers, etc.)","ALL","35 Years","75 Years",{"count":78,"type":79},128,"ESTIMATED","INTERVENTIONAL",[82],"NA","The goal of this randomized controlled trial is to determine the impact of Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) diet and aerobic training on cognition in Black adults with high systolic blood pressure.\n\nResearchers will compare Food Delivery and Cooking PLUS Aerobic Training (FoRKS+) versus Enhanced Usual Care (EUC) to evaluate the effects on cognition.\n\nParticipants will complete cognitive and cardiovascular assessments, 24-hr blood pressure monitoring, standard blood pressure measurements, weight, fingerstick for HbA1c point-of-care testing, and questionnaires.\n\nParticipants may also choose to participate in an optional blood draw for DNA Repair Capacity testing as a modifiable risk factor for aging-associated diseases.",[85,86,87,88],"Cognitive Decline","Hypertension","Diet","Aerobic Exercise",[90,91,92,93],"nutrition","cooking","exercise","hypertension","2026-02-03",{"date":96,"type":97},"2026-02-05","ACTUAL",{"date":99,"type":97},"2023-11-28",{"date":101,"type":79},"2028-05-31",{"name":5,"class":6},1]