[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595112":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":38,"responsibleParty":56,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":25,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Georgetown University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"In-person MSC","EXPERIMENTAL","Mindful Self-Compassion (MSC) is a weekly class given for 8 weeks. The individual classes last about 2 hours each. The class is provided in a group setting.",[13],"Behavioral: Mindful Self-Compassion",{"label":15,"type":16,"description":17,"interventionNames":18},"Video-conference MSC","ACTIVE_COMPARATOR","Mindful Self-Compassion (MSC) is a weekly class given for 8 weeks. The individual classes last about 2 hours each. The class is provided in a video-conference group setting.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Mindful Self-Compassion","The course teaching mindfulness meditation skills relevant to cultivating self-compassion.",[9,15],null,[27],{"name":28,"affiliation":5,"role":29},"Elizabeth Hoge, MD","PRINCIPAL_INVESTIGATOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Charisma Study Coordinator","CONTACT","202-687-7283","anxietyresearch@georgetown.edu",{"name":37,"role":33,"phone":34,"phoneExt":25,"email":35},"Thirein Study Coordinator",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Georgetown University Medical Center","RECRUITING","Washington D.C.","District of Columbia","20007","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-77.03637,38.89511,{"lat":51,"lon":50},[54],{"name":28,"role":33,"phone":34,"phoneExt":25,"email":55},"eah103@georgetown.edu",{"type":29,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Elizabeth Hoge","Professor of Psychiatry","100595112","mindful-self-compassion-for-anxiety-and-depression-impact-of-delivery-method-100595112",false,"NCT07028216","Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method","Mindful Self-Compassion for Anxiety and Depression: A Randomized Comparison of In-Person Versus Videoconference Delivery","Inclusion Criteria:\n\n* Must have a primary anxiety disorder (social anxiety disorder, generalized anxiety disorder, panic disorder, or agoraphobia) or major depressive disorder, current\n* Must score low on self-compassion, as measured by the self-compassion scale\n* Must understand study procedure and willing to participate in all testing visits, and treatment as assigned\n* Must be able to give informed consent to the study procedures\n\nExclusion Criteria:\n\n* Comorbid psychiatric disorder other than anxiety or depression, such as psychotic disorder, obsessive compulsive disorder, eating disorders (i.e., anorexia and bulimia), bipolar disorder; developmental or organic mental disorders; and current (past 6 months) substance use disorders and current post-traumatic stress disorder as assessed by clinician at screening visit\n* A serious medical condition that may result in surgery or hospitalization.\n* A history of head trauma causing prolonged loss of consciousness, or ongoing cognitive impairment\n* Inability to understand study procedures or informed consent process, or significant personality dysfunction likely to interfere with study participation (assessed during the clinical interview).\n* Subjects who will be non-compliant with the study procedures. This may include planned travel out of town.\n* Subjects taking some psychiatric medication such as barbiturates or antipsychotics. Sleep medications and some anti-depressants will be allowed, if the subject has been taken at stable dose 8 weeks prior to baseline and the patient plans to continue at the same dose through the trial.\n* Concurrent psychotherapy initiated within 1 month of screen interview, or ongoing psychotherapy of any duration directed specifically toward the treatment of anxiety (such as Cognitive Behavioral Therapy).\n* Individuals who have completed a course of MSC or an equivalent meditation training in the last year.\n* Individuals reporting significant active suicidal ideation or suicidal behaviors within the past year.\n* Individuals with a medical condition (i.e., epilepsy) that may be exacerbated by study treatment, as determined by a study physician or nurse practitioner based on history, physical, and\u002For labs.\n* Adults unable to consent\n* Pregnant women\n* Prisoners","ALL","18 Years","65 Years",{"count":70,"type":71},80,"ESTIMATED","INTERVENTIONAL",[74],"NA","The study will compare the delivery of an 8-week Mindful Self-Compassion training, in-person against video-conference, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders (generalized anxiety disorder, social anxiety disorder, and panic disorder) or major depressive disorder or dysthymia.",[77,78,79,80,81,82,83],"Anxiety Disorders","Generalized Anxiety Disorder","Social Anxiety Disorder","Panic Disorder","Agoraphobia","Major Depressive Disorder","Persistent Depressive Disorder (Dysthymia)","2026-05-03",{"date":86,"type":87},"2026-05-05","ACTUAL",{"date":89,"type":87},"2025-06-01",{"date":91,"type":71},"2027-08-31",{"name":5,"class":6},1]