[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629630":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":25,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":25,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":25,"enrollmentInfo":63,"targetDuration":25,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":74,"overallStatus":78,"whyStopped":25,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"University of Santiago de Compostela","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mineral trioxide aggregate (MTA) group","EXPERIMENTAL","Participants in this arm will undergo non-surgical endodontic retreatment following standard clinical procedures. After removal of the previous root canal filling and chemomechanical preparation, the root canals will be obturated with mineral trioxide aggregate (MTA). Calcium hydroxide will be used as intracanal medication between visits prior to final obturation.",[13],"Device: Mineral trioxide aggregate (MTA) group",{"label":15,"type":16,"description":17,"interventionNames":18},"Gutta-percha group","ACTIVE_COMPARATOR","Participants in this arm will undergo non-surgical endodontic retreatment following standard clinical procedures. After removal of the previous root canal filling and chemomechanical preparation, the root canals will be obturated with gutta-percha and a resin-based sealer. Calcium hydroxide will be used as intracanal medication between visits prior to final obturation.",[19],"Device: Gutta-percha group",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Root canal obturation performed using mineral trioxide aggregate (MTA) following non-surgical endodontic retreatment. After removal of the previous root canal filling, chemomechanical preparation and irrigation of the root canal system are performed. Calcium hydroxide is used as intracanal medication between visits prior to final obturation with MTA",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Root canal obturation performed using gutta-percha and a resin-based sealer following non-surgical endodontic retreatment. After removal of the previous root canal filling, chemomechanical preparation and irrigation of the root canal system are performed. Calcium hydroxide is used as intracanal medication between visits prior to final obturation with gutta-percha using the continuous wave technique.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Tania Gancedo-Gancedo","CONTACT","+ 34 608439156","tania.gancedo.g@gmail.com",[36],{"facility":37,"status":25,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"School of Medicine and Dentistry","Santiago de Compostela","A Coruña","15705","Spain","ES",{"type":44,"coordinates":45},"Point",[46,47],-8.54569,42.88052,{"lat":47,"lon":46},[50],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"type":52,"investigatorFullName":31,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Principal Investigator, Professor of Endodontics, University of Santiago de Compostela","100629630","mineral-trioxide-aggregate-mta-vs-gutta-percha-for-non-surgical-endodontic-retreatment-in-teeth-with-apical-lesions-100629630",false,"NCT07477171","Mineral Trioxide Aggregate (MTA) vs Gutta-Percha for Non-Surgical Endodontic Retreatment in Teeth With Apical Lesions","Comparison of Two Root Canal Filling Materials in Non-Surgical Endodontic Retreatment: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\nPatients ≥18 years old American Society of Anesthesiologists (ASA) physical status I and II Teeth requiring non-surgical endodontic retreatment Periapical lesion ≤10 mm in maximum diameter on periapical radiograph Apical canal diameter ≤ size 50 Teeth without periodontal defects or mobility\n\nExclusion Criteria:\n\nSmokers Teeth with insufficient remaining tooth structure Teeth requiring surgical retreatment Primary endodontic treatment complications (fractured instrument, perforation, ledge or apical transportation)","ALL","18 Years",{"count":64,"type":65},58,"ESTIMATED","INTERVENTIONAL",[68],"NA","The main objective of this study is to compare the healing rate of periapical lesions after non-surgical endodontic retreatment in teeth obturated with gutta-percha versus those obturated with mineral trioxide aggregate (MTA), with a 12-month follow-up. Secondary objectives include evaluating differences between groups in healing time, postoperative pain, and tooth discoloration.",[71,72,73],"Periapical Diseases","Root Canal Therapy","Mineral Trioxide Aggregate (MTA)",[75,76,77],"non-surgical endodontic retreatment","bioceramic","gutta-percha","NOT_YET_RECRUITING","2026-03-18",{"date":81,"type":82},"2026-03-23","ACTUAL",{"date":84,"type":65},"2026-03",{"date":86,"type":65},"2027-04",{"name":5,"class":6},1]