[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551564":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":28,"locations":39,"responsibleParty":58,"collaborators":27,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":27,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":27,"enrollmentInfo":70,"targetDuration":27,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":27,"overallStatus":42,"whyStopped":27,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Saint-Joseph University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"conventional group","ACTIVE_COMPARATOR","Each canal will be prepared using Reciproc Blue nickel titanium file 25\u002F08 and sonic activation of NaOCl",[13],"Device: a new prototye device that heat and activate sodium hyochlorite (Aseptico)",{"label":15,"type":16,"description":17,"interventionNames":18},"conservative technique","EXPERIMENTAL","in the conservative technique, a size 10 FlexoFile will be introduced ,a glide path will be established using the size 10 FlexoFile to the WL, than Proglider 16.02 to the foramen.\n\nthan heating and activation of NaOCl will be done with a prototype needle",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","a new prototye device that heat and activate sodium hyochlorite (Aseptico)","endoactivator : it is a sonic activator device",[15,9],[26],"Endoactivator (in the conventional group ) -Dentsply",null,[29,35],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Fabienne Roukoz El Jagi, MSc","CONTACT","70510337","+961","fabienne.jagi@net.usj.edu.lb",{"name":36,"role":31,"phone":37,"phoneExt":33,"email":38},"Roula EL Hachem, Phd","03836040","roula.hachem@usj.edu.lb",[40],{"facility":41,"status":42,"city":43,"state":27,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Saint Joseph University","RECRUITING","Beirut","1481","Lebanon","LB",{"type":48,"coordinates":49},"Point",[50,51],35.50157,33.89332,{"lat":51,"lon":50},[54,56],{"name":55,"role":31,"phone":32,"phoneExt":33,"email":34},"fabienne R el Jagi, MSC",{"name":57,"role":31,"phone":37,"phoneExt":33,"email":38},"roula H el hachem, Phd",{"type":59,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR","100551564","minimal-instrumentation-with-intracanal-heating-and-activation-of-sodium-hypochlorite-for-the-management-of-teeth-with-periapical-lesions-100551564",false,"NCT06461728","Minimal Instrumentation With Intracanal Heating and Activation of Sodium Hypochlorite for the Management of Teeth With Periapical Lesions","Minimal Instrumentation With Intracanal Heating ad Activation of Sodium Hypochlorite for","Inclusion Criteria:\n\n* Healthy patients without any known allergic reactions or systemic diseases.\n* Single rooted teeth.\n* Fully formed roots.\n* The ability to place #15 hand file to working length (WL).\n* Absence of canal calcifications.\n* Absence of root fracture.\n* Absence of resorption.\n* Teeth with pre-operative periapical radiolucency and PAI score ≥ 3 according to the classification of Ørstavik et al. 1986(20).\n* Estimated WL 20-23mm.\n\nExclusion Criteria:\n\n* Roots with broken or immature open apices.\n* Roots presenting resorption.\n* Patients younger than 18 years old.\n* Pregnant patients.\n* Teeth with previous root canal treatment.\n* Teeth with calcified canals.\n* Teeth with two canals or any other anatomic variations.\n* Root length less than 16 mm.\n* Patients with chronic generalized periodontitis.\n* Teeth with caries affecting the roots.\n* Abnormal mobility of the tooth.\n* Extensively restored and prepared teeth.\n* Open apices.\n* Previously root canal therapy.\n* Root cracks.",true,"ALL","18 Years",{"count":71,"type":72},32,"ESTIMATED","INTERVENTIONAL",[75],"NA","this study is the first to demonstrate the efficacy of minimally invasive root canal treatment combined with intracanal heating and activation of NaOCl using a prototype needle on the healing of asymptomatic apical periodontitis of necrotic single rooted teeth. 32 teeth will be randomaly assigned into 2 groups :conventional and conservative technique .In the conventional group : each canal will be prepared using Reciproc Blue 25\u002F08, approximetly 27 ml of NaOCl will be used , the canal will be activated using 20.02 taper tip of a sonic decive . This cyclel will be repeated 3 times and the obturation will be done using a single cone technique with AH plus resin-based sealer . In the second group a size 10 k file will be introduced to confirm patency and to record working length after filling the canal with NaOCl. A glide path will be established using the size 10 FlexoFile to the WL, than Proglider 16.02 to the foramen. After the glide path, the canal will be irrigated with 3 ml of 5, 25 % of NaOCL .The prototype needle tip will be placed in the canal to the length that is a little shorter than the length at binding point , in order to heat and activate the irrigant solution for 30 seconds.Step one is repeated 4 more times and a fresh solution of NaOCl is replaced every time. Canals will be dried using sterile paper points size 15 and the obturation will be performed for all teeth using the same technique as group 1 but with a standardized gutta percha point 2% tapered",[78],"Heating and Activation of Sodium Hypochlorite","2024-06-23",{"date":81,"type":82},"2024-06-25","ACTUAL",{"date":84,"type":82},"2023-11-07",{"date":86,"type":72},"2025-06-07",{"name":5,"class":6},1]