[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594473":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":61,"collaborators":64,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":26,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":46,"whyStopped":26,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Minimal Vitrectomy Surgery (MVS)","EXPERIMENTAL","The epiretinal membrane is peeled directly through the intact vitreous. Limited vitrectomy is selectively performed if pre-existing floaters or membrane fragments remain after peeling and cannot be removed safely with forceps.",[13],"Procedure: Minimal Vitrectomy Surgery",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional Vitrectomy (PPV)","ACTIVE_COMPARATOR","Standard pars plana vitrectomy is performed. Posterior vitreous detachment induction and core vitreous removal are conducted before membrane peeling.",[19],"Procedure: Conventional Vitrectomy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Minimal Vitrectomy Surgery","The epiretinal membrane is peeled directly through the intact vitreous. Limited localized vitrectomy is selectively performed if pre-existing floaters or membrane fragments remain after peeling.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Conventional Vitrectomy","Standard pars plana vitrectomy is performed with posterior vitreous detachment induction and core vitreous removal prior to epiretinal membrane peeling.",[15],[32],{"name":33,"affiliation":5,"role":34},"Weihong Yu, MD","PRINCIPAL_INVESTIGATOR",[36,40],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+8613671214306","yuweihongpumch@163.com",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},"Xufeng Zhao","+8619121036553","yezhong019@163.com",[45],{"facility":5,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Beijing","Beijing Municipality","100730","China","CN",{"type":53,"coordinates":54},"Point",[55,56],116.39723,39.9075,{"lat":56,"lon":55},[59],{"name":26,"role":37,"phone":60,"phoneExt":26,"email":43},"19121036553",{"type":34,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Weihong Yu","Professor",[65],{"name":66,"class":6},"Peking Union Medical College","100594473","minimal-vitrectomy-surgery-for-epiretinal-membrane-100594473",false,"NCT07019896","Minimal Vitrectomy Surgery for Epiretinal Membrane","Minimal Vitrectomy Surgery (MVS) Versus Conventional Vitrectomy for the Treatment of Idiopathic Epiretinal Membrane: A Multicenter Randomized Controlled Trial","MVS-ERM","Inclusion Criteria:\n\n1. Age ≥ 18 years.\n2. Diagnosis of idiopathic epiretinal membrane (ERM) confirmed by clinical examination and OCT imaging.\n3. Clear ocular media allowing adequate fundus imaging.\n4. Phakic eye.\n5. Ability and willingness to provide written informed consent.\n\nExclusion Criteria:\n\n1. Prior cataract surgery or advanced cataract requiring combined surgery. Co-existing retinal diseases (e.g., diabetic retinopathy, retinal detachment, retinal vein occlusion).\n2. Systemic conditions preventing safe surgery or follow-up.\n3. History of prior ocular or periocular corticosteroid use, including intraocular injection, periocular injection, or long-term topical corticosteroid eye drops.","ALL","18 Years",{"count":78,"type":79},140,"ESTIMATED","INTERVENTIONAL",[82],"NA","This multicenter randomized controlled trial evaluates Minimal Vitrectomy Surgery (MVS) versus conventional vitrectomy for idiopathic epiretinal membrane (ERM). The primary endpoints include visual acuity improvement and cataract progression after 12 months. MVS aims to minimize vitreous removal while ensuring complete membrane removal through adaptive limited vitrectomy.",[85,86,87],"Epiretinal Membrane","Macular Edema (ME)","Nuclear Cataract",[89,9,90,91],"Idiopathic Epiretinal Membrane (ERM)","Nonvitrectomizing Vitreous Surgery (NVS)","pars plana Vitrectomy (PPV)","2025-06-05",{"date":94,"type":95},"2025-06-13","ACTUAL",{"date":97,"type":95},"2024-12-01",{"date":99,"type":79},"2026-11-30",{"name":5,"class":6},1]