[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100371681":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":55,"locations":64,"responsibleParty":158,"collaborators":160,"id":173,"slug":174,"hasResults":175,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":179,"eligibilityCriteria":180,"healthyVolunteers":175,"sex":181,"minAge":182,"maxAge":183,"enrollmentInfo":184,"targetDuration":25,"studyType":187,"phases":188,"briefSummary":190,"conditions":191,"keywords":193,"overallStatus":112,"whyStopped":25,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":205,"completionDateStruct":207,"leadSponsor":209,"locationsCount":210},{"fullName":5,"class":6},"Clinique Les Trois Soleils","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Conventional Rehabilitation","ACTIVE_COMPARATOR","at least 4 sessions\u002Fweek for 6 weeks, from 1 hour of conventional upper limb rehabilitation by an occupational therapist.",[13],"Other: Conventional rehabilitation",{"label":15,"type":16,"description":17,"interventionNames":18},"Intensive Visual Simulation","EXPERIMENTAL","at least 4 sessions\u002Fweek for 6 weeks, of 1 hour of upper limb rehabilitation including 45 minutes of conventional rehabilitation (occupational therapy) and 15 minutes of work with a medical device allowing intensive visual digital simulation.",[13,19],"Device: Intensive Visual Simulation",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Conventional rehabilitation","upper limb rehabilitation involving submaximal passive amplitude stretching movements, inhibition postures, active efforts assisted of varying difficulty, target approach exercises with or without elbow support and gripping tasks, adapted to the upper limb's paresis abilities. The patient will be encouraged to gradually dispense with the assistance provided by the therapist or any technical assistance (suspension...) and thus to carry out the exercises in free active as soon as possible.",[9,15],null,{"type":27,"name":15,"description":28,"armGroupLabels":29,"otherNames":25},"DEVICE","* First week: observation, mentalization and then attempt to perform the movements on the screen.\n* Second and third weeks: production of analytical movements of wrist flexion\u002Fextension, pronation\u002Fsupination, finger flexion\u002Fextension, thumb opposition.\n* From the 4th week until the end: depending on the patient's motor capacities, continuation of the work of the previous 2 weeks or introduction of more functional work with object manipulation, gripping work.\n\nConventional rehabilitation upper limb rehabilitation involving submaximal passive amplitude stretching movements, inhibition postures, active efforts assisted of varying difficulty, target approach exercises with or without elbow support and gripping tasks, adapted to the upper limb's paresis abilities. The patient will be encouraged to gradually dispense with the assistance provided by the therapist or any technical assistance (suspension...) and thus to carry out the exercises in free active as soon as possible.",[15],[31,34,37,40,43,46,49,52],{"name":32,"affiliation":5,"role":33},"Christophe DURET, MD","PRINCIPAL_INVESTIGATOR",{"name":35,"affiliation":36,"role":33},"Manuel Wiese, MD","Clinalliance Villiers-sur-Orge",{"name":38,"affiliation":39,"role":33},"Nikolay DOBREV, MD","CRF PASORI",{"name":41,"affiliation":42,"role":33},"François BOYER, Professor","Hôpital Sébastopol, CHU de Reims",{"name":44,"affiliation":45,"role":33},"Caroline TERRACOL, MD","Clinique Marienia Inicea",{"name":47,"affiliation":48,"role":33},"Jean-Marc GUEBLE, MD","Clinique Verdaich",{"name":50,"affiliation":51,"role":33},"Adrien PETIT, MD","Clinique Les Grands Chênes Inicea",{"name":53,"affiliation":54,"role":33},"Magali CAPLANNE, MD","Clinique Napoléon Inicea",[56,61],{"name":57,"role":58,"phone":59,"phoneExt":25,"email":60},"SAS Les POMPON","CONTACT","+33164718000","ag.grosmaire@les-trois-soleils.fr",{"name":32,"role":58,"phone":62,"phoneExt":25,"email":63},"+33 164 718 000","direction@les-trois-soleils.fr",[65,95,111,127,141],{"facility":66,"status":67,"city":68,"state":69,"zip":70,"country":71,"countryCode":72,"cosmosGeoPoint":73,"geoPoint":78,"contacts":79},"CHU Sébastopol","NOT_YET_RECRUITING","Reims","Champagne-Ardenne","51092","France","FR",{"type":74,"coordinates":75},"Point",[76,77],4.02853,49.26526,{"lat":77,"lon":76},[80,84,87,90,92,94],{"name":81,"role":58,"phone":82,"phoneExt":25,"email":83},"François BOYER, PhD","+33 326 788 597","fboyer@chu-reims.fr",{"name":85,"role":58,"phone":82,"phoneExt":25,"email":86},"Véronique ROUVROY","vrouvroy@chu-reims.fr",{"name":88,"role":89,"phone":25,"phoneExt":25,"email":25},"Gaël BELASSIAN, MD","SUB_INVESTIGATOR",{"name":91,"role":89,"phone":25,"phoneExt":25,"email":25},"Sandy CARAZO MENDEZ, MD",{"name":93,"role":89,"phone":25,"phoneExt":25,"email":25},"Amandine RAPIN, MD",{"name":81,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":96,"status":67,"city":97,"state":98,"zip":99,"country":71,"countryCode":72,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"Clinique Napoléon","Saint-Paul-lès-Dax","New Aquitaine","40990",{"type":74,"coordinates":101},[102,103],-1.05283,43.72566,{"lat":103,"lon":102},[106,109],{"name":53,"role":58,"phone":107,"phoneExt":25,"email":108},"+33558912200","magali.caplanne@inicea.fr",{"name":110,"role":89,"phone":25,"phoneExt":25,"email":25},"Carole BALVA, MD",{"facility":5,"status":112,"city":113,"state":25,"zip":114,"country":71,"countryCode":72,"cosmosGeoPoint":115,"geoPoint":119,"contacts":120},"RECRUITING","Boissise-le-Roi","77310",{"type":74,"coordinates":116},[117,118],2.56971,48.52479,{"lat":118,"lon":117},[121,124,125],{"name":122,"role":58,"phone":25,"phoneExt":25,"email":123},"Christophe Duret, MD","ch.duret@les-trois-soleils.fr",{"name":122,"role":33,"phone":25,"phoneExt":25,"email":25},{"name":126,"role":89,"phone":25,"phoneExt":25,"email":25},"Laurence MANDON, MD",{"facility":128,"status":112,"city":129,"state":25,"zip":130,"country":71,"countryCode":72,"cosmosGeoPoint":131,"geoPoint":135,"contacts":136},"CRF Pasori","Cosne-Cours-sur-Loire","58200",{"type":74,"coordinates":132},[133,134],2.92528,47.41101,{"lat":134,"lon":133},[137,140],{"name":138,"role":58,"phone":25,"phoneExt":25,"email":139},"Nikolay Dobrev, MD","n.dobrev@pasori.fr",{"name":138,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":142,"status":112,"city":143,"state":25,"zip":144,"country":71,"countryCode":72,"cosmosGeoPoint":145,"geoPoint":149,"contacts":150},"Clinalliance Villiers-sur Orge","Villiers-sur-Orge","91700",{"type":74,"coordinates":146},[147,148],2.30002,48.65953,{"lat":148,"lon":147},[151,153,155,157],{"name":35,"role":58,"phone":25,"phoneExt":25,"email":152},"dr.wiese@villiers.clinalliance.fr",{"name":154,"role":89,"phone":25,"phoneExt":25,"email":25},"Elisabeth Alais, MD",{"name":156,"role":33,"phone":25,"phoneExt":25,"email":25},"Véronique Ediere, MD",{"name":35,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":159,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[161,163,165,167,169,170,172],{"name":36,"class":162},"UNKNOWN",{"name":164,"class":162},"Centre de Rééducation Fonctionnelle Pasori",{"name":166,"class":6},"CHU de Reims",{"name":168,"class":162},"Clinique Les Grands Chênes",{"name":96,"class":162},{"name":171,"class":162},"Clinique Mariénia",{"name":48,"class":162},"100371681","mirror-therapy-rehabilitation-of-the-upper-limb-after-stroke-neuro-miroir-2-100371681",false,"NCT04119544","Mirror Therapy Rehabilitation of the Upper Limb After Stroke (NEURO-MIROIR 2)","Intensive Rehabilitation Program With Intensive Visual Numerical Simulation Device for Improving Distal Motor Performance and Upper Limb Functional Capacity in Subacute Hemiparetics After Stroke. Randomized Controlled Trial.","NEUROMIROIR2","Inclusion Criteria:\n\n* Age ≥18 years;\n* Stroke hemiparesis on unilateral focal lesion dating from 4 to 10 weeks at baseline;\n* Total sub-scores wrist and hand of th Fugl-Meyer \\\u003C 16\n* Patient having agreed to sign an informed consent\n* patient being affiliated to the French Social Security\n\nExclusion Criteria:\n\n* Cognitive dysfunction or progressive intercurrent illness making effective communication or participation in the study impossible\n* Phasic disorders that prevent the understanding of instructions\n* Patient include in an other clinical trial\n* Neurological conditions prior to stroke\n* Patient who had mirror therapy or IVS rehabilitation before inclusion\n* Rheumatological pathology of the hand and wrist\n* Person under legal protection measure.","ALL","18 Years","100 Years",{"count":185,"type":186},66,"ESTIMATED","INTERVENTIONAL",[189],"NA","Hemiparesis is a common motor disorder after a stroke. The majority of patients do not recover functional use of their paretic upper limb.\n\nThe use of mirror therapy allows the activation of the mirror neurons involved to stimulate brain plasticity after brain damage.The IVS (Intensive Visual Stimulation) device allows an easy implementation of mirror therapy by filming the valid upper limb and projecting the inverted image onto a screen placed above the parietal arm thus producing the illusion of movement of the parietal arm.\n\nThe main hypothesis of this study is that the structured practice of a large number of upper limb targeted movement repetitions using an intensive visual numerical simulation device as a partial replacement for routine care (conventional occupational therapy) in the sub-acute phase of stroke will increase the active function (motor function and functional abilities) of the distal end of the upper limb compared to conventional rehabilitation.\n\nObjectives: This randomized controlled trial will evaluate the effects of partial substitution of routine care (occupational therapy) by structured movement repetition programs by Intensive Visual Simulation using an IVS3 device, on the distal motor control of the upper hemiparesis limb, between 4 and 10 weeks after the stroke, compared to a program with conventional care alone.",[192],"Stroke",[194,195,196,197,198,199,200],"stroke","mirror therapy","rehabilitation","hemiparesis","upper limb","function","motor control","2026-03-16",{"date":203,"type":204},"2026-03-18","ACTUAL",{"date":206,"type":204},"2019-12-10",{"date":208,"type":186},"2028-07-31",{"name":5,"class":6},5]