[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641877":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":37,"centralContacts":41,"locations":50,"responsibleParty":83,"collaborators":86,"id":91,"slug":92,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":97,"eligibilityCriteria":98,"healthyVolunteers":99,"sex":100,"minAge":101,"maxAge":102,"enrollmentInfo":103,"targetDuration":12,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":53,"whyStopped":12,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":126},{"fullName":5,"class":6},"University of Cyprus","OTHER",[8,13,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","NO_INTERVENTION","Subjects in this arm will receive no alerts for high temperatures nor recommendations for mitigation of heat-related health effects.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Heat intervention - Personal Alerts and Specific Recommendations","EXPERIMENTAL","Subjects in this group will receive timely personal alerts for high temperatures and specific recommendations to reduce exposure to heat and mitigation of heat-related health effects in written and animated format through mobile phones, mobile applications and online tools.",[18],"Other: Heat intervention",{"label":20,"type":15,"description":21,"interventionNames":22},"Heat and air pollution intervention - Group Alerts, Recommendations and Air Cleaners","Subjects in this group will receive alerts and recommendations as in group \"Heat intervention\" and in addition, continuously use of air cleaners with HEPA filter for removing PM from indoor air in their residences and workplaces to provide evidence for health benefits.",[23],"Other: Heat and air pollution mitigation intervention",[25,31],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Heat intervention","The participants in this group of intervention will receive timely personal alerts for high temperatures and specific recommendations to reduce exposure to heat by changing patterns of time spent and physical activity performed outdoors, regulating indoor temperature using fans and\u002For air conditioning devices, as well as recommendations for mitigation of heat-related health effects (hydration, body cooling) in written and animated format, through mobile phones, web application and online tools to be developed by the project research team",[14],[30],"Behavioral intervention to reduce exposure to heat",{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"Heat and air pollution mitigation intervention","The participants in this intervention group will receive alerts and recommendations as in group \"Heat intervention\" and, in addition, continuously use air cleaners with HEPA filters for removing PM from indoor air in their residences and workplaces.",[20],[36],"Behavioral intervention to reduce exposure to heat and air-pollution",[38],{"name":39,"affiliation":5,"role":40},"Panayiotis Yiallouros, Professor","PRINCIPAL_INVESTIGATOR",[42,46],{"name":39,"role":43,"phone":44,"phoneExt":12,"email":45},"CONTACT","+35722895212","yiallouros.panayiotis@ucy.ac.cy",{"name":47,"role":43,"phone":48,"phoneExt":12,"email":49},"Panayiotis Kouis, PhD","+35722895243","kouis.panayiotis@ucy.ac.cy",[51,68],{"facility":52,"status":53,"city":54,"state":12,"zip":12,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"University of Thessaly","RECRUITING","Trikala","Greece","GR",{"type":58,"coordinates":59},"Point",[60,61],21.76837,39.55493,{"lat":61,"lon":60},[64],{"name":65,"role":43,"phone":66,"phoneExt":12,"email":67},"Andreas Flouris, Professor","+30 24310 47072","aflouris@uth.gr",{"facility":69,"status":53,"city":70,"state":12,"zip":12,"country":71,"countryCode":72,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"University of Léon","León","Spain","ES",{"type":58,"coordinates":74},[75,76],-5.57032,42.60003,{"lat":76,"lon":75},[79],{"name":80,"role":43,"phone":81,"phoneExt":12,"email":82},"Belén Carballo-Leyenda, Professor","+34 987 293 023","abcarl@unileon.es",{"type":40,"investigatorFullName":84,"investigatorTitle":85,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Panayiotis Yiallouros","Professor",[87,90],{"name":88,"class":89},"University of Leon","UNKNOWN",{"name":52,"class":6},"100641877","mitigation-of-health-effects-in-outdoor-workers-by-reducing-exposure-to-heat-and-air-pollution-100641877",false,"NCT07634952","Mitigation of Health Effects in Outdoor Workers by Reducing Exposure to Heat and Air Pollution","Innovative Solutions Across the MEDiterranean for Mitigation of Climate Change-related heaLth rIsks in Outdoor Workers","ISMED-CLIM OW","Inclusion Criteria:\n\n* 18-65 years old\n* Municipality outdoor workers\n* Regularly working outdoors for al least 6 hours per day\n* Living in León (Spain) or Trikala (Greece)\n* Clinically healthy\n* No history of diabetes mellitus type 2 (DM2)\n* No history of arterial hypertension\n\nExclusion Criteria:\n\n* Currently smoking\n* Presence of any smoking residents in the household\n* Not residing at the household for at least 5 days a week\n* Planning to move from the current home within the next two months\n* No access to Wi-Fi or 4G\u002F5G mobile phone\n* Severe chronic conditions (congestive heart failure, ischemic heart disease, significant valvular heart disease, DM2, inflammatory diseases, renal failure, or active cancer)\n* Drugs abuse\n* Alcohol abuse\n* Psychiatric disorders\n* Severe mental disability that interferes with answering questions or following instructions",true,"ALL","18 Years","65 Years",{"count":104,"type":105},102,"ESTIMATED","INTERVENTIONAL",[108],"NA","The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health effects in outdoor workers.\n\nThe main questions it aims to answer are:\n\n* Does the intervention (combination of behavioral recommendations for heat mitigation) reduce personal ambient temperature exposure, measured using a wearable device (iButton)?\n* Does the intervention (combination of behavioral recommendations for air pollution mitigation and use of indoor air cleaners) reduce indoor exposure to air pollution, measured using indoor air quality sensors (Purple Air)?\n* Does the intervention (combination of behavioral recommendations for heat mitigation) reduce physiological strain experienced by individuals working in hot environments, measured using the Heat Strain Score Index?\n\nResearchers will compare measurements between outdoor workers carrying out their activities in the absence of intervention (control group), those carrying out their activities with behavioural recommendations (recommendation intervention group) and those carrying out their activities with both behavioural recommendations for heat mitigation and continuous use of indoor air cleaners in their house (heat and air pollution mitigation intervention group) to see if changes in temperature exposure and physiological strain are different between intervention groups.\n\nParticipants will:\n\n* Wear the wearable devise for continuous personal ambient temperature monitoring (ibutton) daily for a period of three months\n* Have their core temperature measured using an eCelsius medical capsule in three repeated assessments\n* Complete the Heat Strain Score Index questionnaire in three repeated assessments\n* Provide samples of urine, blood, saliva and hair for measurement of various biomarkers in three repeated assessments",[111],"Heat Strain",[113,114,115,116],"outdoor workers","heat strain","intervention","personal ambient temperature exposure","2026-06-12",{"date":119,"type":120},"2026-06-16","ACTUAL",{"date":122,"type":120},"2026-05-01",{"date":124,"type":105},"2027-07-31",{"name":5,"class":6},2]