[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603296":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":26,"responsibleParty":44,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Universitair Ziekenhuis Brussel","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Individuals with long COVID",null,"History of a confirmed or documented SARS-CoV-2 infection and long COVID according to the World Health Organisation's clinical case definition",{"label":13,"type":10,"description":14,"interventionNames":10},"Convalescent individuals","History of a confirmed or documented SARS-CoV-2 infection, complete recovery after the SARS-CoV-2 infection, no history of long COVID according to the World Health Organisation's clinical case definition",[16],{"name":17,"affiliation":18,"role":19},"Elisabeth De Waele, MD. PhD.","Vitality Research Group, Metabolism and Nutrition, Vrije Universiteit Brussel (VUB), Clinical Nutrition Department, Universitair Ziekenhuis Brussel (UZ Brussel)","PRINCIPAL_INVESTIGATOR",[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Berenice G. Jimenez Garcia, Master of Science","CONTACT","+3224749624","berenice.gabriela.jimenez.garcia@vub.be",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Laarbeeklaan 101","RECRUITING","Jette","Brussels Capital","1090","Belgium","BE",{"type":36,"coordinates":37},"Point",[38,39],4.33419,50.87309,{"lat":39,"lon":38},[42],{"name":43,"role":23,"phone":24,"phoneExt":10,"email":25},"Berenice G. Jimenez Garcia, MSc.",{"type":19,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Elisabeth De Waele","Head of the Department of Clinical Nutrition, Co-director of Vitality Research Group","100603296","mitochondrial-function-in-peripheral-blood-mononuclear-cells-muscle-and-skin-of-long-covid-patients-100603296",false,"NCT07134673","Mitochondrial Function in Peripheral Blood Mononuclear Cells, Muscle, and Skin of Long COVID Patients","Mitochondrial Oxygen Consumption and Substrate Utilisation In Vitro in Peripheral Blood Mononuclear Cells, and In Vivo on Muscle and Skin in Long COVID Patients and Convalescent Individuals: A Case-Control and Diagnostic Accuracy Study","MitoLoCo","Individuals with long COVID:\n\nInclusion criteria:\n\n* Long COVID diagnosis, based on the WHO definition;\n* Presence of long COVID symptoms for a minimum of 6 months.\n* History of confirmed or documented SARS-CoV-2 infection.\n* Adult (≥18 years of age).\n* Post-COVID-19 Functional Status Scale grade 2-4, while they had a grade 0 before the SARS-CoV-2 infection.\n\nExclusion criteria:\n\n* Pre-existing chronic diseases potentially affecting the functional status scale.\n* Treatment with metabolism altering drugs.\n* \\> 10 standard units of alcohol (10 grams of alcohol\u002Fglass) per week.\n* Unable to understand oral and written instructions in Dutch, French or English.\n* Allergies to medical adhesive bandages.\n* Porphyria and other skin conditions aggravated by sunlight.\n\nConvalescent individuals\n\nInclusion criteria:\n\n* History of confirmed or documented SARS-CoV-2 infection.\n* Complete recovery after the SARS-CoV-2 infection, no history of long COVID based on the WHO definition;\n* Post-COVID-19 Functional Status Scale \\[2\\] grade 0 both before the infection and currently.\n* Adult (≥18 years of age).\n\nExclusion criteria:\n\n* Pre-existing chronic non-communicable diseases (e.g. hypertension, chronic respiratory diseases, diabetes).\n* Treatment with metabolism altering drugs.\n* \\> 10 standard units of alcohol (10 grams of alcohol\u002Fglass) per week.\n* Unable to understand oral and written instructions in Dutch, French or English.\n* Allergies to medical adhesive bandages.\n* Porphyria and other skin conditions aggravated by sunlight.",true,"ALL","18 Years",{"count":59,"type":60},54,"ESTIMATED","OBSERVATIONAL","Mitochondria are structures inside cells that are responsible for producing energy from nutrients through a series of steps, using oxygen. To have an idea of how well the mitochondria can produce energy, we can measure how much oxygen they use. The goal of this study is to:\n\n1. To compare the oxygen use between people with long COVID and people who completely recovered after COVID-19, using three techniques that measure the oxygen use in blood cells, on the skin and in the muscle\n2. To test how similar these three techniques are in measuring the oxygen used in the three different tissues\n\nParticipants will:\n\n* Complete surveys,\n* Wear an activity tracker (7 days),\n* Undergo several non-invasive tests, and\n* Donate a blood sample The study will take place in UZ Brussel hospital and will take 2 study visits, approximately 7 days apart.",[64,65],"Long COVID","Post-COVID-19 Condition",[67],"mitochondrial dysfunction","2026-04-21",{"date":70,"type":71},"2026-04-22","ACTUAL",{"date":73,"type":71},"2026-01-21",{"date":75,"type":60},"2026-07",{"name":5,"class":6},1]