[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634760":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":32,"locations":10,"responsibleParty":39,"collaborators":42,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":55,"maxAge":10,"enrollmentInfo":56,"targetDuration":59,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":68,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":74,"leadSponsor":76,"locationsCount":10},{"fullName":5,"class":6},"University Hospital of Cologne","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"MitraClip G5 Cohort",null,"All patients undergoing mitral valve transcatheter edge-to-edge repair (M-TEER) using the MitraClip fifth-generation (G5) system at participating centers.",[13],"Device: MitraClip G5",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","MitraClip G5","Fifth-generation MitraClip system for mitral valve transcatheter edge-to-edge repair, used as part of routine clinical care. No study-specific interventions are performed.",[9],[21,25,27,30],{"name":22,"affiliation":23,"role":24},"Philipp von Stein, MD","University Hospital Cologne","PRINCIPAL_INVESTIGATOR",{"name":26,"affiliation":23,"role":24},"Victor Mauri, MD",{"name":28,"affiliation":29,"role":24},"Pier Pasquale Leone, MD, MSc","Montefiore Medical Center",{"name":31,"affiliation":29,"role":24},"Azeem Latib, MD",[33,37],{"name":22,"role":34,"phone":35,"phoneExt":10,"email":36},"CONTACT","646-321-8145","philipp.von-stein@uk-koeln.de",{"name":26,"role":34,"phone":10,"phoneExt":10,"email":38},"victor.mauri@uk-koeln.de",{"type":24,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Philipp von Stein","Principal Investigator, MITRAGEN5 Registry",[43,44],{"name":29,"class":6},{"name":45,"class":6},"Cardiovascular Research Foundation, New York","100634760","mitraclip-generation-5-mitral-valve-transcatheter-edge-to-edge-repair-registry-100634760",false,"NCT07543874","MITRAClip GENeration 5 Mitral Valve Transcatheter Edge-to-Edge Repair Registry","MITRAClip GENeration 5 Mitral Valve Transcatheter Edge-to-Edge Repair Registry (MITRAGEN5 Registry)","MITRAGEN5","Inclusion Criteria:\n\n* Age 18 years or older at the time of M-TEER\n* Treatment using the MitraClip G5 system\n\nExclusion Criteria:\n\n\\- None","ALL","18 Years",{"count":57,"type":58},1000,"ESTIMATED","30 Days","OBSERVATIONAL","The MITRAGEN5 Registry is an international, multicenter, observational registry that collects data on patients with mitral regurgitation who are treated with the fifth-generation MitraClip (G5) device. The MitraClip is a small device used to repair the mitral valve of the heart without open-heart surgery, a procedure called mitral valve transcatheter edge-to-edge repair (M-TEER). This registry aims to evaluate how safe and effective the MitraClip G5 is in everyday clinical practice across multiple hospitals worldwide. All procedures, tests, and follow-up visits are part of routine clinical care. No additional study-specific procedures are performed. Data are collected in anonymized form from participating centers.",[63],"Mitral Regurgitation",[65,66,67,17],"MitraClip","Mitral Valve Transcatheter Edge-to-Edge Repair","M-TEER","NOT_YET_RECRUITING","2026-04-27",{"date":71,"type":72},"2026-05-01","ACTUAL",{"date":71,"type":58},{"date":75,"type":58},"2030-12-31",{"name":5,"class":6}]