[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567656":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":25,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":25,"enrollmentInfo":48,"targetDuration":25,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":25,"overallStatus":58,"whyStopped":25,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":25},{"fullName":5,"class":6},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ropivacaine","ACTIVE_COMPARATOR","Popliteal block using Ropivacaine 100 mg in 20 mL",[13],"Drug: Ropivacaine 0,5%",{"label":15,"type":16,"description":17,"interventionNames":18},"Ropivacaine anmd Lidocaine","EXPERIMENTAL","Popliteal sciatic block using Ropivacaine 100 mg and Lidocaine 100 mg in 20 mL",[19],"Drug: Ropivacaine and Lidocaine",[21,26],{"type":22,"name":23,"description":17,"armGroupLabels":24,"otherNames":25},"DRUG","Ropivacaine and Lidocaine",[15],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Ropivacaine 0,5%","Popliteal sciatic block using ropivacaine 0.5% 20 mL",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Cheng Lin","CONTACT","5196858500","cheng.lin@lhsc.on.ca",{"type":37,"investigatorFullName":32,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Anesthesiologist","100567656","mixed-local-for-sciatic-block-100567656",false,"NCT06671028","Mixed Local for Sciatic Block","Ropivacaine Versus Ropivacaine With Lidocaine Mixture in Poplitial-Sciatic Nerve Block for Below Knee Surgeries- A Randomized, Single Center Study","Inclusion Criteria:\n\n* Adult patients (≥18 years old)\n* Scheduled for elective below-knee surgeries such as ankle arthroscopy, lower limb fracture fixation, toe surgeries, etc\n* Capable of providing informed consent\n\nExclusion Criteria:\n\n* History of allergic reaction to local anesthetics\n* Pre-existing neurological disorders affecting lower limbs\n* Significant renal or hepatic impairment\n* Pregnancy or breastfeeding\n* Less than 60kg\n* Inability to provide informed consent","ALL","18 Years",{"count":49,"type":50},110,"ESTIMATED","INTERVENTIONAL",[53],"NA","Choice of local anesthetics is the major determinant of the characteristics of a peripheral nerve block. Short acting local anesthetics while provides faster onset suffer from shorter duration. On the other hand, long acting local anesthetics while provides long duration suffered from long onset time. The ideal local anesthetics should provide faster nerve block onset while providing reasonable duration to provide sustained postoperative analgesia. Mixing short and long acting local anesthetics for nerve blocks may appear to be the solution however previous published studies have demonstrated similar onset time to long acting local anesthetics and with reduced duration. Recently, the London Health Sciences Centre established an ambulatory surgical centre. Fast onset peripheral nerve block is desirable. Previous studies have not looked at popliteal sciatic block and anecdotally we feel addition of short acting local anesthetics appear to speed up onset. We are therefore interested in conducting a randomize trial to determine whether mixing short and long acting local anesthetics can speed up onset of surgical quality block.",[56,57],"Regional Anesthesia","Local Anesthetic","NOT_YET_RECRUITING","2024-10-31",{"date":61,"type":62},"2024-11-04","ACTUAL",{"date":64,"type":50},"2025-01-01",{"date":66,"type":50},"2027-07-01",{"name":5,"class":6}]