[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100508654":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":37,"centralContacts":42,"locations":48,"responsibleParty":64,"collaborators":30,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":30,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":30,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":87,"overallStatus":51,"whyStopped":30,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Chang Gung Memorial Hospital","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Virtual Reality-based Mirror Therapy (VR+MT)","EXPERIMENTAL","In each therapy session, the patients will execute 2 upper-limb functional tasks, starting with easy then more complex tasks.",[13],"Behavioral: Virtual Reality-based Mirror Therapy (VR+MT)",{"label":15,"type":10,"description":16,"interventionNames":17},"Mixed Reality-based Mirror Therapy (MR+MT)","The patients will execute 2 upper-limb functional tasks in each session.",[18],"Behavioral: Mixed Reality-based Mirror Therapy (MR+MT)",{"label":20,"type":21,"description":22,"interventionNames":23},"Traditional Mirror Therapy (MT)","ACTIVE_COMPARATOR","The patients will execute 2 to 3 categories of activities per training session: (1) active range of motion exercises, (2) reaching movement or object manipulation, and (3) upper-limb functional tasks.",[24],"Behavioral: Traditional Mirror Therapy (MT)",[26,31,34],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","In this VR+MT group, the patients will be instructed to perform the unilateral movements of the non-affected upper limb simultaneously while observing the animated hand as mirroring reflection of the affected hand within the immersive environment, which presented on the goggle via the VR+MT system.",[9],null,{"type":27,"name":15,"description":32,"armGroupLabels":33,"otherNames":30},"In the MR+MT group, the patients will be instructed to perform the unilateral movements of the non-affected upper limb concurrently meanwhile watching the real-time mirroring image reflection of the non-affected upper limb's movements of the patients captured, transformed, and superimposed on the affected upper limb, which projected to the screen from the front side via the MR+MT system.",[15],{"type":27,"name":20,"description":35,"armGroupLabels":36,"otherNames":30},"In the traditional MT group, patients will be instructed to perform the unilateral movements of the non-affected upper limb at the same time while watching the mirror of a mirror box placed in front of the patient's midsagittal plane, in which the illusory reflection of the non-affected upper limb appears as if it were the another affected upper limb.",[20],[38],{"name":39,"affiliation":40,"role":41},"Yu-Wei Hsieh, PhD","Department of Occupational Therapy, College of Medicine, Chang Gung University","PRINCIPAL_INVESTIGATOR",[43],{"name":39,"role":44,"phone":45,"phoneExt":46,"email":47},"CONTACT","+886-3-2118800","3820","ywhsieh@mail.cgu.edu.tw",[49],{"facility":50,"status":51,"city":52,"state":30,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Taoyuan Chang Gung Memorial Hospital","RECRUITING","Taoyuan City","333","Taiwan","TW",{"type":57,"coordinates":58},"Point",[59,60],121.29696,24.99368,{"lat":60,"lon":59},[63],{"name":39,"role":44,"phone":45,"phoneExt":46,"email":47},{"type":65,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100508654","mixed-reality-and-virtual-reality-technology-with-mirror-therapy-for-stroke-rehabilitation-100508654",false,"NCT05903235","Mixed Reality and Virtual Reality Technology With Mirror Therapy for Stroke Rehabilitation","Technology-based and Activity-based Design of Mirror Therapy Principles: Two Mixed Reality and Virtual Reality Mirrored-hand Systems for Stroke Rehabilitation","Phase Ⅰ: Design and Development of the VR+MT and MR+MT Systems \\& Feasibility Study\n\nInclusion Criteria:\n\n* diagnosed with unilateral stroke\n* age of 20 to 80 years\n* a baseline Fugl-Meyer Assessment of the Upper Extremity score of 20 to 60\n* able to follow the study instructions and provide the feedback of user experiences verbally\n\nExclusion Criteria:\n\n* diagnosed with global or receptive aphasia\n* the presence of severe neglect\n* the existence of major medical problems or comorbidities that could interfere with upper-limb usage and pain, or disrupt visual or auditory perception\n\nPhase Ⅱ: Validation and Comparison of Clinical Treatment Efficacy\n\nInclusion Criteria:\n\n* diagnosed with unilateral stroke\n* more than 6 months after stroke onset\n* age of 20 to 80 years\n* a baseline Fugl-Meyer Assessment of the Upper Extremity score of 20 to 60\n* able to follow the study instructions\n* capable of participating in the assessment process and treatment program\n\nExclusion Criteria:\n\n* diagnosed with global or receptive aphasia\n* the presence of severe neglect\n* the existence of major medical problems or comorbidities that could interfere with upper-limb usage and pain, or disrupt visual or auditory perception","ALL","20 Years","80 Years",{"count":77,"type":78},45,"ESTIMATED","INTERVENTIONAL",[81],"NA","The specific study aims will be:\n\n1. To design and develop the hardware and software of the VR+MT and MR+MT systems.\n2. To test the feasibility of the VR+MT and MR+MT systems from the patients and to collect the feedback of users with respect to their experiences.\n3. To examine the treatment effects of VR+MT and MR+MT compared to the traditional MT (i.e., control group) in patients with stroke by conducting a randomized controlled trial.\n4. To identify who will be the possible good responders to VR+MT and MR+MT based on their baseline motor functions and mental imagery abilities.",[84,85,86],"Stroke","Cerebrovascular Disorders","Central Nervous System Diseases",[88,89,90,91,92],"digital rehabilitation","mixed reality","virtual reality","cerebrovascular accident","mirror visual feedback","2026-03-18",{"date":95,"type":96},"2026-03-20","ACTUAL",{"date":98,"type":96},"2024-03-13",{"date":100,"type":78},"2026-07-31",{"name":5,"class":6},1]