[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613745":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":38,"responsibleParty":92,"collaborators":95,"id":99,"slug":100,"hasResults":101,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":101,"sex":107,"minAge":108,"maxAge":18,"enrollmentInfo":109,"targetDuration":18,"studyType":112,"phases":113,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":130},{"fullName":5,"class":6},"Catholic University of the Sacred Heart","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"7-weeks Internet-based interventions","EXPERIMENTAL","Participants allocated to the experimental group will be asked to complete one module per week, each based on the core principles of Acceptance and Commitment Therapy (ACT). The treatment program consists of seven modules delivered weekly over a total duration of seven weeks. The content of the modules will cover the following topics:\n\n1. Creative hopelessness\n2. Willingness and acceptance of pain\n3. Defusion from negative thoughts\n4. Committed action and values\n5. Values and goal setting\n6. Willingness exercises\n7. Maintenance of learned strategies.",[13],"Other: Internet-based intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"7-Weeks Waiting list","NO_INTERVENTION","Participants allocated to the waiting list control group will not receive the intervention during the initial seven-week study period. However, they will be granted full access to the treatment program after the seven weeks have elapsed.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Internet-based intervention","Participants allocated to the experimental group will be asked to complete one module per week, each based on the core principles of Acceptance and Commitment Therapy (ACT). The treatment program consists of seven modules delivered weekly over a total duration of seven weeks. The content of the modules will cover the following topics: 1. Creative hopelessness 2. Willingness and acceptance of pain 3. Defusion from negative thoughts 4. Committed action and values 5. Values and goal setting 6. Willingness exercises 7. Maintenance of learned strategies.",[9],[25],{"name":26,"affiliation":27,"role":28},"Gianluca Castelnuovo, Ph.D.","Catholic University of Sacred Heart of Milan","PRINCIPAL_INVESTIGATOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},"Michelle Semonella","CONTACT","+972559876070","michelle.semonella@unicatt.it",{"name":36,"role":32,"phone":18,"phoneExt":18,"email":37},"Giada Pietrabissa","giada.pietrabissa@unicatt.it",[39,55,66,78],{"facility":40,"status":41,"city":42,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Alma Mater Studiorum of Bologna","RECRUITING","Bologna","Italy","IT",{"type":46,"coordinates":47},"Point",[48,49],11.33875,44.49381,{"lat":49,"lon":48},[52],{"name":53,"role":32,"phone":18,"phoneExt":18,"email":54},"Silvana Grandi","silvana.grandi@unibo.it",{"facility":56,"status":41,"city":57,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"Catholic University of Sacred Heart","Milan",{"type":46,"coordinates":59},[60,61],12.59836,42.78235,{"lat":61,"lon":60},[64],{"name":26,"role":32,"phone":18,"phoneExt":18,"email":65},"gianluca.castelnuovo@unicatt.it",{"facility":67,"status":41,"city":68,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"University of Verona","Verona",{"type":46,"coordinates":70},[71,72],10.9938,45.43854,{"lat":72,"lon":71},[75],{"name":76,"role":32,"phone":18,"phoneExt":18,"email":77},"Lidia Del Piccolo","lidia.delpiccolo@univr.it",{"facility":79,"status":41,"city":80,"state":18,"zip":18,"country":81,"countryCode":82,"cosmosGeoPoint":83,"geoPoint":87,"contacts":88},"University of Linkoping","Linköping","Sweden","SE",{"type":46,"coordinates":84},[85,86],15.62157,58.41086,{"lat":86,"lon":85},[89],{"name":90,"role":32,"phone":18,"phoneExt":18,"email":91},"Gerhard Andersson","gerhard.andersson@liu.se",{"type":28,"investigatorFullName":93,"investigatorTitle":94,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Gianluca Castelnuovo","Professor",[96],{"name":97,"class":98},"Linkoeping University","OTHER_GOV","100613745","mobact-an-internet-based-intervention-for-chronic-pain-patients-100613745",false,"NCT07270588","MobACT: An Internet-Based Intervention for Chronic Pain Patients","MOBACT: An Internet-Based Guided Self-Help Intervention Based on Acceptance and Commitment Therapy for Chronic Pain","MobACT","Inclusion Criteria:\n\n1. Adults aged 18 years or older;\n2. A verifiable medical diagnosis of Chronic Pain (duration ≥ 3 months);\n3. Internet access;\n4. Sufficient computer and internet literacy;\n5. Fluent knowledge of the Italian language.\n\nExclusion Criteria:\n\n1. Current participation in psychological or psychotherapeutic treatments for chronic pain management;\n2. High risk of suicide;\n3. Cognitive impairments;\n4. Presence of certified psychiatric disorders, such as:\n\n   1. Psychotic disorders (e.g., schizophrenia, schizoaffective disorders, etc.);\n   2. Bipolar disorder (unstabilized manic or hypomanic episodes);\n   3. Severe depressive disorders (e.g., major depression, suicidal intent, or recent suicide attempts);\n   4. Severe personality disorders that impair the ability to carry out daily activities (e.g., work, self-care);\n   5. Cognitive or neurodegenerative disorders.","ALL","18 Years",{"count":110,"type":111},140,"ESTIMATED","INTERVENTIONAL",[114],"NA","Chronic Pain (CP) is a condition characterized by pain lasting or recurring for more than three months, often accompanied by emotional distress and difficulties in daily functioning. CP represents a major burden for individuals and healthcare systems due to its impact on quality of life, healthcare utilization, and work productivity. Traditional treatments, such as pharmacological and surgical approaches, frequently provide insufficient relief, highlighting the need for complementary interventions.\n\nAmong psychological approaches, Acceptance and Commitment Therapy (ACT) has shown promising results for CP management. ACT aims to increase psychological flexibility by helping individuals accept pain as part of their experience while engaging in meaningful, value-based activities. Rather than focusing exclusively on symptom reduction, ACT promotes emotional well-being, functioning, and quality of life. However, access to psychological interventions remains limited because of barriers such as long waiting lists, geographical distance, physical limitations, stigma, and limited availability of trained professionals.\n\nDigital health interventions, particularly internet-delivered self-help programs, may help overcome these barriers by providing flexible, accessible, and cost-effective support. Previous research suggests that ACT can be effectively adapted to online formats, allowing broader dissemination and increased accessibility for individuals with CP.\n\nThe present study aims to evaluate the effectiveness of a guided internet-delivered ACT-based self-help intervention for individuals with CP. The intervention seeks to support pain acceptance, improve quality of life, and promote engagement in valued activities. The study will also explore potential psychological mechanisms underlying treatment outcomes and assess the cost-effectiveness of the intervention to evaluate its potential implementation within public healthcare systems.",[117],"Chronic Pain",[117,21,119,120],"clinical psychology","acceptance and commitment therapy","2026-05-15",{"date":123,"type":124},"2026-05-19","ACTUAL",{"date":126,"type":124},"2025-10-01",{"date":128,"type":111},"2027-10-30",{"name":5,"class":6},4]