[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523380":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":43,"responsibleParty":60,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":25,"maxAge":25,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mobile Anger Reduction Intervention (MARI)","EXPERIMENTAL","Participants in this arm will download the MARI application (app) on their own smart phone device and will use the app for a period of 4 weeks.",[13],"Behavioral: Mobile Anger Reduction Intervention (MARI)",{"label":15,"type":16,"description":17,"interventionNames":18},"Health Education Condition (HED)","ACTIVE_COMPARATOR","Participants in this arm will download the HED application (app) on their own smart phone device and will use the app for a period of 4 weeks.",[19],"Behavioral: Health Education Condition (HED)",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","This is a mobile intervention that uses interpretation bias modification (IBM) techniques to reduce the hostile interpretation bias. Participants will download the MARI app and be instructed to complete at least 5 treatment sessions each week for a period of 4 weeks. Each session takes approximately 10 minutes. The app also includes a Nightly Diary to track symptoms, a calendar to program session reminders, and a My Progress feature to track use and performance.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"This is a mobile application that delivers videos with psychoeducation about healthy habits and selfcare for general wellness. Participants will download the HED app and be instructed to use it at least 5 times a week for a period of 4 weeks.",[15],[30],{"name":31,"affiliation":32,"role":33},"Kirsten H Dillon, PhD","Durham VA Medical Center, Durham, NC","PRINCIPAL_INVESTIGATOR",[35,39],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","(919) 286-0411","Kirsten.Dillon@va.gov",{"name":40,"role":36,"phone":37,"phoneExt":41,"email":42},"Angela C Kirby, MS","7456","angela.kirby@va.gov",[44],{"facility":32,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Durham","North Carolina","27705-3875","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-78.89862,35.99403,{"lat":55,"lon":54},[58,59],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},{"name":31,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":61,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100523380","mobile-anger-reduction-intervention-100523380",false,"NCT06094933","Mobile Anger Reduction Intervention","A Randomized Controlled Trial of the Mobile Anger Reduction Intervention for Veterans","MARI","Inclusion Criteria:\n\n* Veterans diagnosed with PTSD, established via chart review and a score of greater than or equal to 33 on the PTSD Checklist for DSM-5 (PCL-5)\n* Reporting a score of greater than or equal to 12 on the 5-item Dimensions of Anger Reactions Scale\n* Have not had any changes to type or dose of psychiatric medications for 3 months, with no plans to make adjustments in the next 6 months\n* Able to read at least 6th grade level material\n\nExclusion Criteria:\n\n* Currently in a period of active psychosis or mania\n* Exhibit current prominent suicidal or homicidal ideation requiring immediate intervention\n* Have used the MARI application before as part of another research study\n* Receiving (or plan to receive) other anger management psychotherapy or trauma-focused therapy for PTSD (i.e., prolonged exposure, cognitive processing therapy during the course of the study","ALL",{"count":72,"type":73},150,"ESTIMATED","INTERVENTIONAL",[76],"NA","Difficulty controlling anger is the most commonly reported reintegration concern among combat Veterans, especially those with a diagnosis of posttraumatic stress disorder (PTSD). Problematic anger is associated with significant functional impairment. In the current project, the investigators will compare the Mobile Anger Reduction Intervention (MARI) with a health education mobile intervention (HED) among Veterans with PTSD and problematic anger. Participants will be randomized to the MARI or HED condition. The hypothesis is that participants in the MARI condition will experience greater anger reductions and functional improvements relative to the HED condition.",[79,80],"Posttraumatic Stress Disorder","Anger",[82,83,84,85],"posttraumatic stress disorder","anger","hostile interpretation bias","mHealth","2025-10-15",{"date":88,"type":89},"2025-10-20","ACTUAL",{"date":91,"type":89},"2024-11-12",{"date":93,"type":73},"2028-03-31",{"name":5,"class":6},1]