[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558310":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":40,"responsibleParty":59,"collaborators":62,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":70,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":24,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":24,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Vanderbilt University Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"mHealth Intervention","ACTIVE_COMPARATOR","Patients will be randomized to the mHealth texting platform, which are messages designed to facilitate self-awareness, reinforce step targets, and link physical activity with a reward or memorable cue.",[13],"Device: mHealth Intervention",{"label":15,"type":6,"description":16,"interventionNames":17},"Usual Care","Routine medical care",[18],"Device: Usual Care",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Our HIPPA-compliant texting platform is linked to the Fitabase Interface. Real time activity data are transmitted from the participant's smartphone to Fitabase via cellular network. Participants will receive 3-5 texts\u002Fday in sync with their preferred schedule defined at enrollment and taking into account school schedules as relevant. These texts use personal, disease-specific, and provider information to deliver two types of messages customized to the current step count and sent in equal proportion. Messages are designed to facilitate self-awareness, reinforce step targets, and link physical activity with a reward or memorable cue.",[9],null,{"type":21,"name":15,"description":16,"armGroupLabels":26,"otherNames":24},[15],[28],{"name":29,"affiliation":5,"role":30},"Eric Austin, MD","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":24,"email":36},"Natasha Billard","CONTACT","(434) 851-3306","natasha.billard.1@vumc.org",{"name":29,"role":34,"phone":38,"phoneExt":24,"email":39},"(615) 343-7617","eric.austin@vumc.org",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Nashville","Tennessee","37232","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-86.78444,36.16589,{"lat":52,"lon":51},[55,57,58],{"name":33,"role":34,"phone":56,"phoneExt":24,"email":36},"434-851-3306",{"name":29,"role":34,"phone":38,"phoneExt":24,"email":39},{"name":29,"role":30,"phone":24,"phoneExt":24,"email":24},{"type":30,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Eric Austin","Director, Vanderbilt Pediatric Pulmonary Hypertension Program (Allergy\u002FImmunology\u002FPulmonary Medicine) and Associate Professor of Pediatrics (Allergy\u002FImmunology\u002FPulmonary Medicine)",[63,65],{"name":64,"class":6},"University of California, San Francisco",{"name":66,"class":67},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100558310","mobile-health-intervention-to-improve-exercise-in-pediatric-ph-100558310",false,"NCT06549452","Mobile Health Intervention to Improve Exercise in Pediatric PH","MhOVE-PPH Study: Mobile Health Intervention to Improve Exercise in Pediatric PH","MhOVE-PPH","Inclusion Criteria:\n\n* Adolescents between ages 10-21 years.\n* Diagnosed with WHO Group 1 PAH or WHO Group 4 PH (CTEPH)\n* WHO functional class I-III\n* Stable PAH-specific medication regimen for three months prior to enrollment. Subjects with only a single diuretic adjustment in the prior three months will be included. Adjustments in IV prostacyclin for side effect management are allowed.\n\nExclusion Criteria:\n\n* Prohibited from normal activity due to wheelchair bound status, bed bound status, reliance on a cane\u002Fwalker, activity-limiting angina, activity-limiting osteoarthritis, or other condition that limits activity.\n* Pregnancy\n* Diagnosis of PAH etiology other than idiopathic, heritable, or associated.\n* Functional class IV heart failure\n* Requirement of \\> 2 diuretic adjustment in the prior three months.\n* Preferred form of activity is not measured by an activity tracker (swimming, yoga, ice skating, stair master, or activities on wheels such as bicycling or rollerblading).\n* Involved in any other investigational intervention.","ALL","10 Years","21 Years",{"count":80,"type":81},50,"ESTIMATED","INTERVENTIONAL",[84],"NA","Children and adults with pulmonary arterial hypertension (PAH) have severely reduced daily activity compared to healthy populations. In adults, investigators recently demonstrated that lower baseline daily step counts associated with increased risk of hospitalization and worsening WHO functional class; similarly, reduced step counts associate with hospitalization in children with PAH. This application builds on our recently completed NIH-funded pilot mobile health (mHealth) trial in adult patients with PAH which demonstrated the ability to remotely increase step counts. The investigators now aim to: (1) adapt our mHealth intervention to the developmental needs and interests of adolescents; and, (2) determine if our intervention increases step counts in adolescents, providing the foundation for a larger trial to assess the impact on quality of life and clinical outcomes.",[87],"Pulmonary Arterial Hypertension","2026-03-24",{"date":90,"type":91},"2026-03-27","ACTUAL",{"date":93,"type":91},"2024-12-01",{"date":95,"type":81},"2030-11-01",{"name":5,"class":6},1]