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intervention (eMocha DOT app)",[13],"Other: DOT intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of care","NO_INTERVENTION","Adolescent patients who continue enhanced goal-setting standard of care",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"DOT intervention","A mobile health application developed by eMocha Health Inc. facilitates asynchronous mobile video directly observed therapy (DOT) intervention, empowering users to track dose-by-dose medication adherence",[9],[25],{"name":26,"affiliation":5,"role":27},"Dipankar Gupta, MD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":18,"email":32},"CONTACT","352-273-5422","dgupta@ufl.edu",{"name":34,"role":30,"phone":35,"phoneExt":18,"email":36},"Dalia Lopez-Colon, 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Medicine","NOT_YET_RECRUITING","Tallahassee","32306",{"type":47,"coordinates":93},[94,95],-84.28073,30.43826,{"lat":95,"lon":94},[98,102,105],{"name":99,"role":30,"phone":100,"phoneExt":18,"email":101},"Mike Killian, PhD","850-644-7094","mkillian@fsu.edu",{"name":103,"role":30,"phone":18,"phoneExt":18,"email":104},"Sonnie Mayewski","smayewski@fsu.edu",{"name":99,"role":27,"phone":18,"phoneExt":18,"email":18},{"type":107,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[109,111],{"name":110,"class":6},"emocha Mobile Health, Inc.",{"name":112,"class":113},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100495559","mobile-video-directly-observed-therapy-dot-for-immunosuppression-medication-adherence-in-adolescent-heart-transplant-recipients-100495559",false,"NCT05732779","Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients","Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients: Enhancing Technological Innovation and Strengthening the Role of Small Businesses in Meeting Needs of Adolescent Organ Transplant","Inclusion Criteria:\n\n* Eligible participants are 10-21 years of age\n* Have received a heart transplant and are followed participating pediatric heart transplant centers\n* English-speaking or Spanish-speaking\n* Own a smart-phone or have access to the mobile app through other devices\n* Are willing to receive information through it\n* Have a MLVI score of greater than 2.0 over the last year\n\nExclusion Criteria:\n\n• Those with cognitive impairments will not be eligible for enrollment due to inability to provide informed assent","ALL","10 Years","21 Years",{"count":125,"type":126},100,"ESTIMATED","INTERVENTIONAL",[129],"NA","We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality. Herein, we propose an innovative approach to promote medication adherence and improve patient and graft outcomes.",[132,133,134,135,136,137,138],"Heart Transplant Rejection","Immune Suppression","Pediatric Heart Transplant","Medication Nonadherence","Health Behavior","Remote Monitoring","Patient Engagement","2026-02-24",{"date":141,"type":142},"2026-02-27","ACTUAL",{"date":144,"type":142},"2024-10-01",{"date":146,"type":126},"2027-05-01",{"name":5,"class":6},4]