[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100506465":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":29,"responsibleParty":46,"collaborators":48,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":10,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":10,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Newcastle-upon-Tyne Hospitals NHS Trust","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Control Cohort",null,"Control participants who are age- and gender-matched to the PD cohort",{"label":13,"type":10,"description":14,"interventionNames":10},"PD Cohort","PD Patients who have completed their participation in the Mobilise-D Clinical Validation Study",[16],{"name":17,"affiliation":18,"role":19},"Alison Yarnall, PhD","Newcastle University","PRINCIPAL_INVESTIGATOR",[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Isabel K Neatrour, MSc","CONTACT","+44 (0) 191 2081406","isabel.neatrour@newcastle.ac.uk",{"name":17,"role":23,"phone":27,"phoneExt":10,"email":28},"+44 (0)191 2081279","alison.yarnall@newcastle.ac.uk",[30],{"facility":31,"status":32,"city":33,"state":10,"zip":10,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"The Newcastle upon Tyne Hospitals NHS Foundation Trust","RECRUITING","Newcastle upon Tyne","United Kingdom","UK",{"type":37,"coordinates":38},"Point",[39,40],-1.61396,54.97328,{"lat":40,"lon":39},[43,45],{"name":44,"role":23,"phone":10,"phoneExt":10,"email":10},"Philip Brown",{"name":17,"role":19,"phone":10,"phoneExt":10,"email":10},{"type":47,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[49,51,53,55,58],{"name":50,"class":6},"KU Leuven",{"name":52,"class":6},"University of Kiel",{"name":54,"class":6},"University Hospital Erlangen",{"name":56,"class":57},"Tel-Aviv Sourasky Medical Center","OTHER_GOV",{"name":59,"class":6},"University College Dublin","100506465","mobilise-d-extension-study-100506465",false,"NCT05874739","Mobilise-D: Extension Study","Validating a Digital Mobility Assessment in Parkinson's Disease Using Wearable Technology - the Mobilise-D Extension Study.","Control Cohort:\n\nInclusion Criteria:\n\n* Aged 50 years or over\n* Able to walk 4 meters independently without walking aids\n* Anticipated availability for 12 months.\n* Ability to consent and comply with any study specific procedures.\n* Willingness to wear a wearable sensor for mobility monitoring\n* Able to read and write in first language in the respective country\n\nExclusion Criteria:\n\n* Occurrence of any of the following within 3 months prior to informed consent: myocardial infarction, hospitalization for unstable angina, stroke, coronary artery bypass graft (CABG), percutaneous coronary intervention (PCI), implantation of a cardiac resynchronization therapy device (CRTD), active treatment for cancer or other malignant disease, uncontrolled congestive heart disease (NYHA class \\>3), acute psychosis or major psychiatric disorders or continued substance abuse, other neurological or orthopaedic impairment that significantly impacts on gait\n* Patients with a clinical diagnosis of PD, COPD, proximal hip fracture or MS\n* History of dementia\u002Fsignificant cognitive impairment, or movement disorder (including essential tremor)\n\nPD Cohort\n\nInclusion Criteria:\n\n* Participant in the Mobilise-D Clinical Validation Study (CVS) PD Cohort - see below.\n\nCVS PD Cohort:\n\nInclusion criteria:\n\n* Aged 18 or over\n* Patients with the clinical diagnosis of PD according to the recent criteria of the Movement Disorder Society\n* Hoehn \\& Yahr stage I-III\n\nExclusion Criteria:\n\n* History consistent with Dementia with Lewy Bodies (DLB), atypical parkinsonian syndromes (including multiple system atrophy or progressive supranuclear palsy, diagnosed according to accepted criteria)\n* Repeated strokes or stepwise progression of symptoms, leading to a diagnosis of 'vascular parkinsonism'\n* Drug-induced Parkinsonism",true,"ALL","18 Years",{"count":71,"type":72},651,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate the ability of a mobility monitor to measure and predict outcomes in Parkinson's disease (PD). It is an extension of a previous study (the Mobilise-D Clinical Validation Study) and consists of an additional follow-up visit for PD participants and the recruitment of age matched control participants. The data will inform researchers about PD disease progression and normal changes in mobility associated with aging.",[76,77],"Parkinson Disease","Aging","2024-07-05",{"date":80,"type":81},"2024-07-08","ACTUAL",{"date":83,"type":81},"2023-05-17",{"date":85,"type":72},"2025-07-28",{"name":5,"class":6},1]