[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571530":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":33,"responsibleParty":51,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":10,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Children having heart surgery",null,"Children under 18 years of age having heart surgery with cardio-pulmonary bypass at Boston Children's Hospital",[13],"Other: blood sampling",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"blood sampling","Discarded blood samples will be taken from routine clinical labs drawn during and after heart surgery.",[9],[20],{"name":21,"affiliation":5,"role":22},"Koichi Yuki, MD","PRINCIPAL_INVESTIGATOR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Jocelyn Booth, BSN","CONTACT","857-218-4585","jocelyn.booth@childrens.harvard.edu",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Rachel Bernier, MPH","857-218-5348","rachel.bernier@childrens.harvard.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-71.05977,42.35843,{"lat":45,"lon":44},[48,49,50],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},{"name":21,"role":22,"phone":10,"phoneExt":10,"email":10},{"type":22,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Koichi Yuki","MD","100571530","modeling-blood-management-and-hemolytic-risk-in-pediatric-heart-surgery-100571530",false,"NCT06721455","Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery","Mathematical Modeling of Salvaged Red Blood Cells-based Blood Management Strategy and Their Hemolytic Risk in Pediatric Cardiac Surgery","Inclusion Criteria:\n\n* pediatric patients under 18 years of age undergoing cardiac surgery with clear prime on cardio-pulmonary bypass (CPB) at Boston Children's Hospital (BCH).\n\nExclusion Criteria:\n\n* patients with known hemolytic disorders, patients on nitric oxide preoperatively, and patients found to have abnormal coagulation on routine preoperative assessment. Patients receiving heparin, American Society of Anesthesia (ASA) status, apixaban, warfarin, or bivalirudin held appropriately (i.e. for elective surgery) will not be excluded","ALL","0 Years","17 Years",{"count":65,"type":66},50,"ESTIMATED","OBSERVATIONAL","This study aims to learn more about blood management in children undergoing heart surgery, such as the right amounts, and the best blood products, to administer. It also aims to develop a mathematical model that may help researchers better predict and treat patients who need blood transfusions during heart surgery.",[70,71,72],"Heart Surgery","Blood Transfusion","Hemolysis","2026-01-05",{"date":75,"type":76},"2026-01-07","ACTUAL",{"date":78,"type":76},"2025-08-01",{"date":80,"type":66},"2026-12-31",{"name":5,"class":6},1]