[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609366":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":53,"collaborators":56,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":25,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Virginia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MindTrails-Movement CBM-I Condition","EXPERIMENTAL","The intervention group (N=68) will include participants with Huntington's disease (N=34) and Parkinson's disease (N=34). Participants will download the MindTrails-Movement app with active CBM-I training condition and will be prompted to complete brief, daily CBM-I training sessions for a period of 6 weeks. They will complete surveys assessing mood symptoms and interpretation bias at baseline, end of week 2, end of week 4, and end of week 6 (end of intervention), then again at the end of week 10.",[13],"Behavioral: MindTrails-Movement",{"label":15,"type":6,"description":16,"interventionNames":17},"Waitlist Control Condition","The waitlist control group (N=68) will include participants with Huntington's disease (N=34) and Parkinson's disease (N=34). Participants will be asked to download a control version of the app that includes access to a list of support resources but does not include daily CBM-I training content. They will complete surveys assessing mood symptoms and interpretation bias at baseline, end of week 2, end of week 4, and end of week 6, and end of week 10. Waitlist control participants will be offered the opportunity to complete the intervention version of the app after they complete their final study assessments.",[18],"Other: Waitlist Control",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","MindTrails-Movement","CBM-I training app with active CBM-I training condition",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Waitlist Control","Version of MindTrails-Movement app including surveys and list of support resources but without active CBM-I training component",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Jessie Gibson, PhD, RN","CONTACT","434-924-0107","MindTrailsMovement@uvahealth.org",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Univeristy of Virginia School of Nursing","RECRUITING","Charlottesville","Virginia","22903","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-78.47668,38.02931,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"type":54,"investigatorFullName":32,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Assistant Professor",[57],{"name":58,"class":59},"National Institute of Nursing Research (NINR)","NIH","100609366","modification-of-threat-interpretation-bias-to-reduce-anxiety-in-neurodegenerative-movement-disorders-aim-3-100609366",false,"NCT07213648","Modification of Threat Interpretation Bias to Reduce Anxiety in Neurodegenerative Movement Disorders (Aim 3)","Inclusion Criteria:\n\n* Clinical diagnosis of Huntington's disease or Parkinson's disease (genetic diagnosis of HD also acceptable)\n* With anxiety symptoms (NeuroQoL Anxiety ≥12)\n\nExclusion Criteria:\n\n* Cognitive decline precluding ability to consent or complete the intervention (MoCA 5 min\u002Ftelephone ≤11)\n* Unable to read and understand English\n* Does not have regular access to an internet-connected device, capable of downloading and installing the mobile application (i.e., tablet or iPhone running iOS 10 or later or an Android phone running Android 5.0 or later)\n* Not located in the USA\n* \\\u003C21 years old\n* Active suicidality based on the answer \"yes\" to questions 4, 5, or 6b of the Columbia-Suicide Severity Rating Scale (Screen version)","ALL","21 Years",{"count":69,"type":70},136,"ESTIMATED","INTERVENTIONAL",[73],"NA","The purpose of this study is to assess preliminary efficacy of a tailored cognitive bias modification for interpretation (CBM-I) app for reducing anxiety in Huntington's disease and Parkinson's disease.",[76,77],"Huntington Disease","Parkinson Disease",[79,80,81,82,83,84,85],"CBM-I","cognitive bias modification","interpretation bias","anxiety","mobile app","Huntington","Parkinson","2025-11-20",{"date":88,"type":89},"2025-11-21","ACTUAL",{"date":86,"type":89},{"date":92,"type":70},"2026-09",{"name":5,"class":6},1]