[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618647":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":38,"locations":44,"responsibleParty":93,"collaborators":95,"id":104,"slug":105,"hasResults":106,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":20,"eligibilityCriteria":110,"healthyVolunteers":106,"sex":111,"minAge":112,"maxAge":113,"enrollmentInfo":114,"targetDuration":42,"studyType":117,"phases":118,"briefSummary":120,"conditions":121,"keywords":123,"overallStatus":131,"whyStopped":42,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":141},{"fullName":5,"class":6},"Vastra Gotaland Region","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Nordic Crohn´s Disease Exclusion Diet","EXPERIMENTAL","2 weeks of total enteral nutrition followed by 3 phases (6 weeks each) of a Nordic Crohn´s Disease Exclusion Diet.",[13],"Other: Nordic Crohn´s Disease Exclusion Diet",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"OTHER","The study consists of 20 weeks of dietary intervention, divided into four phases, followed by a 4-week follow-up period. The intervention begins with a 2-week period of liquid nutrition, after which unprocessed foods are gradually introduced while liquid nutrition is progressively reduced over three consecutive 6-week phases. The diet is specifically designed to exclude pro-inflammatory ingredients and emphasize gut-friendly foods. In the final phase, participants are allowed consume most unprocessed foods, along with up to two meals per week containing products with food additives.",[9],[20,21],"N-CDED","Nordic-CDED",[23,27,30,34],{"name":24,"affiliation":25,"role":26},"Stine Störsrud, RD, PhD","Dept of Molecular & Clinical Medicine, Sahlgrenska Academy, Univ of Gothenburg, Sweden","STUDY_CHAIR",{"name":28,"affiliation":29,"role":26},"Elin Malmgren Hård af Segerstad, Ped Diet, PhD","Pediatric Research Institute, Oslo Univ Hosp, Norway; Clinical Sciences, Lund Univ, Malmö, Sweden",{"name":31,"affiliation":32,"role":33},"Karl Mårild, MD, PhD","Dept of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg","STUDY_DIRECTOR",{"name":35,"affiliation":36,"role":37},"Nalleli Vivanco Karlsson, Ped Diet, PhD","Dept of Pediatrics, Skaraborg Hosp, Skövde, Sweden; Sahlgrenska Academy, Gothenburg","PRINCIPAL_INVESTIGATOR",[39],{"name":35,"role":40,"phone":41,"phoneExt":42,"email":43},"CONTACT","+46 70 412 7142",null,"nalleli.vivanco.karlsson@vgregion.se",[45,65,80],{"facility":46,"status":42,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Skånes University Hospital","Malmö","Skåne County","214 28","Sweden","SE",{"type":53,"coordinates":54},"Point",[55,56],13.00073,55.60587,{"lat":56,"lon":55},[59,63],{"name":60,"role":40,"phone":61,"phoneExt":42,"email":62},"Elin Malmberg Hård Af Segerstad, Ped Diet, PhD","+46 40 33 72 80","elin.malmberg_hard_af_segerstad@med.lu.se",{"name":64,"role":37,"phone":42,"phoneExt":42,"email":42},"Elin Malmberg Hård af Segerstad, Ped Diet, PhD",{"facility":66,"status":42,"city":67,"state":42,"zip":68,"country":50,"countryCode":51,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Queen Silvia's Children's and Adolescent Hospital","Gothenburg","41685",{"type":53,"coordinates":70},[71,72],11.96679,57.70716,{"lat":72,"lon":71},[75,78],{"name":31,"role":40,"phone":76,"phoneExt":42,"email":77},"+46 765 88 72 77","karlmarild@gmail.com",{"name":31,"role":79,"phone":42,"phoneExt":42,"email":42},"SUB_INVESTIGATOR",{"facility":81,"status":42,"city":82,"state":42,"zip":83,"country":50,"countryCode":51,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Skaraborg Hospital Skövde, Pediatric Clinic","Skövde","54949",{"type":53,"coordinates":85},[86,87],13.84506,58.39118,{"lat":87,"lon":86},[90],{"name":91,"role":40,"phone":92,"phoneExt":42,"email":43},"Nalleli Vivanco Karlsson, PhD","0046 704127142",{"type":94,"investigatorFullName":42,"investigatorTitle":42,"investigatorAffiliation":42,"oldNameTitle":42,"oldOrganization":42},"SPONSOR",[96,98,100,102],{"name":97,"class":16},"Skane University Hospital",{"name":99,"class":16},"Sahlgrenska University Hospital",{"name":101,"class":16},"Göteborg University",{"name":103,"class":6},"Skaraborg Hospital","100618647","modified-vs-standard-cded-evaluation-of-a-nordic-adaptation-of-nutritional-therapy-in-paediatric-crohns-disease-100618647",false,"NCT07334340","Modified vs Standard CDED: Evaluation of a Nordic Adaptation of Nutritional Therapy in Paediatric Crohn's Disease","Modified vs Standard Crohn´s Disease Exclusion Diet: Evaluation of a Nordic Adaptation of Nutritional Therapy in Paediatric Crohn's Diseas","Inclusion Criteria:\n\n* Children aged 6-18 years with recent (\\\u003C36 months) mild-to-severe CD diagnosis (defined as Paediatric Crohn's Disease Activity Index \\[PCDAI\\] 15-47.5)\n* Evidence of active inflammation (C-reactive protein \\[CRP\\] ≥ 0.5 mg\u002FdL, erythrocyte sedimentation rate \\[ESR\\] ≥ 20 mm\u002Fh, and\u002For faecal calprotectin \\[FCP\\] ≥ 200 mg\u002Fg during screening)\n* Stable use of medication other than steroids.\n\nExclusion Criteria:\n\n* Eating disorders,\n* Active extraintestinal manifestations\n* Use of systemic corticosteroids\n* Active perianal disease\n* Positive stool cultures for pathogens, parasites, or Clostridioides difficile\n* Fever \\>38.3°C\n* Documented cow's milk protein allergy\n* Diabetes, celiac disease and\u002For psychosocial difficulties.","ALL","6 Years","18 Years",{"count":115,"type":116},30,"ESTIMATED","INTERVENTIONAL",[119],"NA","The primary aim of this clinical trial is to evaluate the clinical effectiveness of the Nordic Crohn's Disease Exclusion Diet (Nordic CDED) in children with Crohn's disease, measured by remission rates, and to compare these outcomes with those reported for the original CDED in similar pediatric populations and study designs.\n\nThe secondary objectives are to assess whether the Nordic CDED can facilitate greater individualization of the diet, improve treatment adherence, and enhance quality of life.\n\nThe study seeks to answer the following key questions:\n\n* Does the Nordic CDED achieve the same clinical effectiveness as the original CDED?\n* Does the Nordic CDED improve adherence and quality of life in children with Crohn's disease? To address these questions, researchers will compare outcomes from children following the Nordic CDED with published results from similar studies of the original CDED, as well as with patients who were not treated with a dietary intervention.\n\nParticipant Involvement:\n\n* Follow the Nordic CDED for 20 weeks.\n* Attend clinic visits at weeks 2, 8, 14, 20, and 24 for checkups and tests.\n* Report adherence to the diet through food records.\n* Report quality of life at the beginning and end of the study",[122],"Pediatric Crohns Disease",[124,125,126,127,128,129,130],"Pediatric gastroenterology","Crohn´s Disease","Enteral nutrition","Nutritional therapy","whole food","nordic CDED","CDED","NOT_YET_RECRUITING","2026-01-05",{"date":134,"type":135},"2026-01-12","ACTUAL",{"date":137,"type":116},"2026-02-01",{"date":139,"type":116},"2030-01-01",{"name":5,"class":6},3]