[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100540915":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":24,"locations":25,"responsibleParty":50,"collaborators":24,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":24,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":24,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":28,"whyStopped":24,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Rutgers, The State University of New Jersey","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Single-pulse Peak Phase TMS","EXPERIMENTAL","Participants will receive a single active TMS pulse during the peak phase target of each task trial and delivered at 110% of participants' resting motor threshold over the predefined frontal target . For the second TMS session, participants will receive single pulse Sham TMS during the peak phase target of each task trial and delivered at 110% of participants' resting motor threshold over the predefined frontal target. Total number of TMS pulse for each session is 520 pulses",[13],"Device: Single pulse TMS to the frontal cortex",{"label":15,"type":10,"description":16,"interventionNames":17},"Single-pulse Trough Phase TMS","Participants will receive a single active TMS pulse during the trough phase target of each task trial and delivered at 110% of participants' resting motor threshold over the predefined frontal target . For the second TMS session, participants will receive single pulse Sham TMS during the peak phase target of each task trial and delivered at 110% of participants' resting motor threshold over the predefined frontal target. Total number of TMS pulse for each session is 520 pulses",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Single pulse TMS to the frontal cortex","Single pulse TMS will be delivered to the left frontal cortex, and stimulation intensity will be at 110% of resting motor threshold.",[9,15],null,[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Rutgers University - Newark","RECRUITING","Newark","New Jersey","07102","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-74.17237,40.73566,{"lat":38,"lon":37},[41,46],{"name":42,"role":43,"phone":44,"phoneExt":24,"email":45},"Travis E Baker, PhD","CONTACT","862-250-3351","travis.e.baker@rutgers.edu",{"name":47,"role":43,"phone":48,"phoneExt":24,"email":49},"Daniel Robles, PhD","973-353-3509","dr1147@newark.rutgers.edu",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Travis Baker, PhD","Associate Professor","100540915","modulating-reward-learning-using-transcranial-magnetic-stimulation-100540915",false,"NCT06323057","Modulating Reward Learning Using Transcranial Magnetic Stimulation","Inclusion Criteria:\n\n* Be between the ages of 18 and 55 years old.\n* Be in stable mental and physical health.\n* If female, test non-pregnant.\n* Be willing to provide informed consent.\n* Be able to comply with protocol requirements and likely to complete all study procedures.\n\nExclusion Criteria:\n\n* Contraindication to rTMS (history of neurological disorder or seizure, increased intracranial pressure, brain surgery, or head trauma with loss of consciousness for \\> 15 minutes, implanted electronic device, metal in the head, or pregnancy).\n* History of autoimmune, endocrine, viral, or vascular disorder affecting the brain.\n* Life time history of mental disorders such as: Bipolar Affective disorder (BPAD), Schizophrenia, Post-traumatic Stress disorder (PTSD) or Dementia or Major Depression.\n* uninterruptable central nervous system medication",true,"ALL","18 Years","55 Years",{"count":65,"type":66},28,"ESTIMATED","INTERVENTIONAL",[69],"NA","Our specific aim is to examine the effects of TMS on reward processing during goal-directed behavior. In these experiments the investigators will utilize a scalp-recorded brain oscillation called frontal midline theta that is believed to index the sensitivity of the cingulate cortex to reward feedback. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in decision making tasks, and if so, whether it would affect the encoding of rewards and subsequent choices during task performance.",[72],"Behavior",[74,75,76,77],"transcranial magnetic stimulation","reward processing","EEG","theta","2025-11-14",{"date":80,"type":81},"2025-11-18","ACTUAL",{"date":83,"type":81},"2024-02-14",{"date":85,"type":66},"2026-04-30",{"name":5,"class":6},1]