[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573645":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":10,"centralContacts":30,"locations":36,"responsibleParty":56,"collaborators":10,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":79,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"National Council of Scientific and Technical Research, Argentina","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy",null,"Volunteers: Adults aged 18-60 years with normal or corrected vision, no clinical history of photosensitive epilepsy, psychiatric disorders, significant hearing loss, migraines, or substance abuse.\n\nInterventions:\n\nPositive sham-neurofeedback Negative sham-neurofeedback Control (no feedback)",[13,14,15],"Other: Positive sham neurofeedback","Other: Negative sham neurofeedback","Other: Control",[17,22,26],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"OTHER","Positive sham neurofeedback","Participants receive simulated positive reinforcement feedback designed to mimic successful modulation of EEG alpha rhythms, despite the feedback not being directly based on their actual neural activity. This condition aims to create the perception of improved attentional control.",[9],{"type":18,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"Negative sham neurofeedback","Participants receive simulated negative reinforcement feedback that mimics unsuccessful modulation of EEG alpha rhythms, regardless of their actual neural activity. This condition is intended to simulate reduced attentional control.",[9],{"type":18,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"Control","Participants perform the same attentional task but without receiving any feedback. This condition serves as a baseline to evaluate the effects of the sham neurofeedback interventions on EEG alpha rhythm modulation.",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"José Alberto Biurrun Manresa, PhD","CONTACT","+543434975100120","jose.biurrun@uner.edu.ar",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Facultad de Ingeniería, Universidad Nacional de Entre Ríos","RECRUITING","Oro Verde","Entre Ríos Province","3100","Argentina","AR",{"type":46,"coordinates":47},"Point",[48,49],-60.51633,-31.82462,{"lat":49,"lon":48},[52,54],{"name":32,"role":33,"phone":53,"phoneExt":10,"email":35},"+543434975100",{"name":32,"role":55,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":55,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"José Biurrun Manresa","Principal Investigator","100573645","modulation-of-cortical-brain-activity-during-attentional-control-100573645",false,"NCT06748976","Modulation of Cortical Brain Activity During Attentional Control","EEG Alpha Rhythm Modulation Using Sham Neurofeedback During Attentional Control in a Virtual Reality Environment","Inclusion Criteria:\n\n* Adults aged between 18 and 60 years.\n* Normal or corrected vision.\n* Ability to provide written informed consent.\n\nExclusion Criteria:\n\n* Diagnosed with photosensitive epilepsy.\n* Significant hearing loss or diagnosed hearing impairment.\n* Current psychiatric illness or disorder.\n* History of migraines or chronic headaches.\n* History of substance or alcohol abuse.\n* Currently pregnant.\n* Discomfort with using a virtual reality headset, assessed during a pilot session.",true,"ALL","18 Years","60 Years",{"count":71,"type":72},35,"ESTIMATED","OBSERVATIONAL","The goal of this study is to determine whether an open-loop sham neurofeedback system can effectively modulate EEG alpha rhythms, which are associated with attentional control. The main questions it aims to answer are:\n\nDoes positive sham neurofeedback lead to a decrease in relative EEG alpha power compared to a control condition without feedback?\n\nResearchers will compare the effects of positive and negative sham-neurofeedback conditions to a control condition without feedback to assess the system's impact on alpha rhythm modulation. Participants will:\n\nExperience three conditions (positive sham-neurofeedback, negative sham-neurofeedback, and no feedback) within a virtual reality environment.\n\nUndergo EEG recordings to measure changes in alpha power as a marker of attentional resource allocation.\n\nProvide written informed consent and complete the study following ethical guidelines.\n\nThis study seeks to explore the potential of open-loop feedback systems to enhance attentional control by modulating alpha rhythm.",[76,77,78],"Rumination","Chronic Pain","Fibromyalgia",[80,81,82,83,84],"operant conditioning","rumination","metacognition","neurofeedback","selective attention","2025-09-22",{"date":87,"type":88},"2025-09-25","ACTUAL",{"date":90,"type":88},"2025-07-01",{"date":92,"type":72},"2025-11",{"name":5,"class":6},1]