[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100141042":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":25,"responsibleParty":49,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":54,"sex":58,"minAge":10,"maxAge":59,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Children's National Research Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patient samples",null,"Fresh-frozen and fixed tumor samples, correspondent normal brain tissue samples, cerebrospinal fluid, urine, and serum samples from patients affected with diffuse intrinsic pontine glioma or brainstem glioma",[13],{"name":14,"affiliation":5,"role":15},"Javad Nazarian, PhD","PRINCIPAL_INVESTIGATOR",[17,21],{"name":14,"role":18,"phone":19,"phoneExt":10,"email":20},"CONTACT","202-476-6022","JNazarian@cnmc.org",{"name":22,"role":18,"phone":23,"phoneExt":10,"email":24},"Caroline Kopsidas, BS","240-393-3359","ckopsidas@childrensnational.org",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Children's National Medical Center","RECRUITING","Washington D.C.","District of Columbia","20010","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-77.03637,38.89511,{"lat":38,"lon":37},[41,42,45,47],{"name":14,"role":15,"phone":10,"phoneExt":10,"email":10},{"name":43,"role":44,"phone":10,"phoneExt":10,"email":10},"Roger Packer, MD","SUB_INVESTIGATOR",{"name":46,"role":44,"phone":10,"phoneExt":10,"email":10},"Suresh Magge, MD",{"name":48,"role":44,"phone":10,"phoneExt":10,"email":10},"Amanda L Muhs, MD",{"type":15,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Javad Nazarian","Associate Professor","100141042","molecular-analysis-of-samples-from-patients-with-diffuse-intrinsic-pontine-glioma-and-brainstem-glioma-100141042",false,"NCT01106794","Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma","Inclusion Criteria:\n\n* Patients of any age with clinical and radiologic diagnosis of diffuse intrinsic pontine glioma\n* Patients with other high-grade gliomas originating in the brainstem\n* Patients with focal gliomas (WHO grade I\u002FII) of the brainstem\n\nExclusion Criteria:\n\n* Patients with any type of infiltrative low grade (WHO grade I and II) or high grade glioma (WHO grade III and IV) originating outside the brainstem\n* Patients harboring primary brainstem tumors with other histologic diagnoses (e.g., PNET)","ALL","21 Years",{"count":61,"type":62},100,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to prospectively collect specimens from pediatric patients with diffuse intrinsic pontine glioma or brainstem glioma, either during therapy or at autopsy, in order to characterize the molecular abnormalities of this tumor.",[66,67],"Diffuse Intrinsic Pontine Glioma","Brainstem Glioma",[69,70,71,72,73,74],"diffuse intrinsic pontine glioma","DIPG","childhood brainstem glioma","pediatric brainstem glioma","brainstem glioma","BSG","2024-08-19",{"date":77,"type":78},"2024-08-20","ACTUAL",{"date":80,"type":78},"2010-04",{"date":82,"type":62},"2030-04",{"name":5,"class":6},1]