[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552237":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":53,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":10,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":10,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Dongzhimen Hospital, Beijing","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Phlegm-heat syndrome",null,"Phlegm-heat syndrome: the score of \"Phlegm-dampness syndrome\" ≥10 and the score of \"Internal fire syndrome\" ≥10 in Diagnostic Scale for Syndrome Elements of Ischemic Stroke.",[13],"Drug: Guideline-based treatment",{"label":15,"type":10,"description":16,"interventionNames":17},"Non-phlegm-heat syndrome","Non-phlegm-heat syndrome: the score of \"Phlegm-dampness syndrome\" \\\u003C10 and the score of \"Internal fire syndrome\" \\\u003C10 in Diagnostic Scale for Syndrome Elements of Ischemic Stroke.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Guideline-based treatment","Guideline-based treatment includes anti-platelet therapy, control of vascular risk factors, and so on.",[15,9],[25],"Routine care",[27],{"name":28,"affiliation":5,"role":29},"Ying Gao, M.D.","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Xinxing Lai, M.D.","CONTACT","8615901111280","new-star@163.com",[37],{"facility":38,"status":10,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Dongzhimen Hospital","Beijing","Beijing Municipality","100700","China","CN",{"type":45,"coordinates":46},"Point",[47,48],116.39723,39.9075,{"lat":48,"lon":47},[51],{"name":32,"role":33,"phone":52,"phoneExt":10,"email":35},"08615901111280",{"type":29,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Ying Gao","Professor","100552237","molecular-characteristics-of-phlegm-heat-syndrome-in-ischemic-stroke-100552237",false,"NCT06470477","Molecular Characteristics of Phlegm-heat Syndrome in Ischemic Stroke","Molecular Characteristics of Phlegm-heat Syndrome in Ischemic Stroke: A Cohort Study","Inclusion Criteria:\n\n* Acute ischemic stroke.\n* Symptom onset within 72 hours.\n* Diagnosis of phlegm-heat syndrome or non-phlegm-heat syndrome.\n* Male or female ≥18 years and ≤ 80 years.\n* With written informed consent.\n\nExclusion Criteria:\n\n* Acute infectious diseases or acute exacerbations of chronic diseases within one month before enrollment.\n* Patients has previous stroke.\n* Other conditions that lead to motor dysfunction (e.g., severe osteoarthritis, rheumatoid arthritis).\n* Renal or hepatic insufficiency, tumors, immune diseases, severe underlying diseases.\n* Other conditions that affect the collection and evaluation of clinical information (e.g., severe aphasia, mental illness).","ALL","18 Years","80 Years",{"count":67,"type":68},84,"ESTIMATED","OBSERVATIONAL","The molecular characteristics of ischemic stroke with phlegm-heat syndrome and candidate biomarkers were identified based on multi-omics data. The main purpose of this study is to validate the molecular characteristics and biomarkers of phlegm-heat syndrome in ischemic stroke, and to demonstrate the association of biomarkers with clinical outcomes.",[72],"Ischemic Stroke, Acute","NOT_YET_RECRUITING","2024-06-17",{"date":76,"type":77},"2024-06-24","ACTUAL",{"date":79,"type":68},"2024-06-20",{"date":81,"type":68},"2024-12-31",{"name":5,"class":6},1]