[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100283303":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":38,"locations":47,"responsibleParty":75,"collaborators":77,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":10,"maxAge":10,"enrollmentInfo":91,"targetDuration":10,"studyType":94,"phases":10,"briefSummary":95,"conditions":96,"keywords":10,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Imagine Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with MRKH syndrome",null,"Biological samples for patients.\n\nInclusion of patients presenting MRKH syndrome, and who are followed in clinical centres participating in the study.",[13],"Genetic: Biological samples for patients",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy relatives","Biological samples for healthy relatives.\n\nInclusion of healthy relatives of patients included in the study (parents, brothers, sisters)",[18],"Genetic: Biological samples for healthy relatives",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"GENETIC","Biological samples for patients","Blood samples. Sampling of uterine tissue during surgical intervention (collection of samples for the study only if samples remain after the routine care analyses)",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"Biological samples for healthy relatives","Blood samples.",[15],[30,34],{"name":31,"affiliation":32,"role":33},"Stanislas Lyonnet","Institut Imagine","STUDY_DIRECTOR",{"name":35,"affiliation":36,"role":37},"Michel Polak","Necker - Enfants malades hospital","PRINCIPAL_INVESTIGATOR",[39,43],{"name":31,"role":40,"phone":41,"phoneExt":10,"email":42},"CONTACT","+33 1 44 49 51 36","stanislas.lyonnet@inserm.fr",{"name":44,"role":40,"phone":45,"phoneExt":10,"email":46},"Anna Pelet","+33 1 42 75 43 08","anna.pelet@inserm.fr",[48,66],{"facility":36,"status":49,"city":50,"state":10,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Paris","75015","France","FR",{"type":55,"coordinates":56},"Point",[57,58],2.3488,48.85341,{"lat":58,"lon":57},[61,63],{"name":35,"role":40,"phone":10,"phoneExt":10,"email":62},"michel.polak@aphp.fr",{"name":64,"role":40,"phone":10,"phoneExt":10,"email":65},"Magali Viaud","magali.viaud@aphp.fr",{"facility":67,"status":49,"city":50,"state":10,"zip":10,"country":52,"countryCode":53,"cosmosGeoPoint":68,"geoPoint":70,"contacts":71},"Institut Mutualiste Montsouris",{"type":55,"coordinates":69},[57,58],{"lat":58,"lon":57},[72],{"name":73,"role":40,"phone":10,"phoneExt":10,"email":74},"Christine Louis-Sylvestre","christine.louis-sylvestre@imm.fr",{"type":76,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[78],{"name":79,"class":80},"Reference center for rare diseases (Rare Gynecologic Diseases)","UNKNOWN","100283303","molecular-genetic-study-of-mayer-rokitansky-kuster-hauser-syndrome-100283303",false,"NCT02967822","Molecular Genetic Study of Mayer-Rokitansky-Kuster-Hauser Syndrome","Etude de Génétique moléculaire du Syndrome de Mayer-Rokitansky-Kuster-Hauser","MRKH","Inclusion Criteria:\n\n* Patient with MRKH syndrome OR healthy relative of patient included\n* Having signed the Informed consent form (or parents in case of patient under 18 years)\n\nExclusion Criteria:\n\n* Refusal to participate in genetic analyses\n* Participation in a therapeutical clinical study in the 30 days prior to inclusion in the present study.",true,"ALL",{"count":92,"type":93},410,"ESTIMATED","OBSERVATIONAL","In order to understand the molecular mechanisms leading to Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH), the research team has to identify molecular bases of this anomaly.\n\nToward this goal, the research team would like to include in the study patients with MRKH syndrome, as well as their healthy relatives, in order to perform genetic analyses, especially whole exome sequencing.\n\nThis study has been set up in order to collect biological samples from patients with MRKH and their relatives.",[97],"Mayer Rokitansky Kuster Hauser Syndrome","2018-10-10",{"date":100,"type":101},"2018-10-12","ACTUAL",{"date":103,"type":10},"2016-05",{"date":105,"type":93},"2031-05",{"name":5,"class":6},2]