[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100242268":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":25,"responsibleParty":47,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":52,"sex":56,"minAge":10,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Indiana University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Heterotaxy and congenital heart defects",null,"Patients and family members with heterotaxy and related congenital heart defects",[13],{"name":14,"affiliation":5,"role":15},"Stephanie M. Ware, MD, PhD","PRINCIPAL_INVESTIGATOR",[17,22],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"Sarah K. Murphy, MPH","CONTACT","317-278-3026","bankssk@iu.edu",{"name":14,"role":19,"phone":23,"phoneExt":10,"email":24},"317-278-2807","stware@iu.edu",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Indiana University School of Medicine","RECRUITING","Indianapolis","Indiana","46202","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-86.15804,39.76838,{"lat":38,"lon":37},[41,45],{"name":42,"role":19,"phone":43,"phoneExt":10,"email":44},"Lindsey R Helvaty, BA, BS","317-278-3020","lhelvaty@iu.edu",{"name":46,"role":19,"phone":23,"phoneExt":10,"email":24},"Stephanie M Ware, MD, PhD",{"type":15,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Stephanie Ware","Professor of Pediatrics and Medical and Molecular Genetics","100242268","molecular-genetics-of-heterotaxy-and-related-congenital-heart-defects-100242268",false,"NCT02432079","Molecular Genetics of Heterotaxy and Related Congenital Heart Defects","Inclusion Criteria:\n\n* Subjects with heterotaxy and related congenital heart defects\n* Family members of subjects with heterotaxy and related congenital heart defects\n\nExclusion Criteria:\n\n* Subjects without heterotaxy and related congenital heart defects\n* Family members of subjects without heterotaxy and related congenital heart defects","ALL",{"count":58,"type":59},2000,"ESTIMATED","OBSERVATIONAL","The goal of this study is to obtain specimens and data from individuals and their families with heterotaxy and related congenital heart defects in order to clarify the molecular genetics of this disorder. The knowledge gained from the analysis of this information will provide the basis for future genetic counseling as well as contribute to knowledge about the biology of normal and abnormal development of left-right anatomic asymmetry.",[63,64],"Heterotaxy Syndrome","Congenital Heart Defects",[66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90],"Abnormalities, Multiple","Asplenia","Bilary Atresia","Birth Defect","Cardiovascular Abnormalities","Cardiovascular Diseases","Congenital Abnormalities","Congenital Heart Disease","Dextrocardia Syndrome","Disturbed Internal Organ Positioning","Genetics","Genetic Testing","Heart Defects, Congenital","Heart Diseases","Heterotaxy syndrome","Intestinal malrotation","Laterality","Left Atrial Isomerism","Pediatrics","Polysplenia","Right Atrial Isomerism","Splenic Diseases","Cilia","Situs inversus","Dextrocardia","2026-06-17",{"date":93,"type":94},"2026-06-22","ACTUAL",{"date":96,"type":10},"2009-07",{"date":98,"type":59},"2030-12",{"name":5,"class":6},1]