[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100487377":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":17,"locations":23,"responsibleParty":42,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":10,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":10,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Dongzhimen Hospital, Beijing","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Phlegm-heat syndrome in ischemic stroke",null,"Phlegm-heat syndrome: the score of \"Phlegm-dampness syndrome\" ≥10 with the score of \"Internal fire syndrome\" ≥10 in Diagnostic Scale for Syndrome Elements of Ischemic Stroke",{"label":13,"type":10,"description":14,"interventionNames":10},"Non-phlegm-heat syndrome in ischemic stroke","Non-phlegm-heat syndrome: the score of \"Phlegm-dampness syndrome\" \\\u003C10 with the score of \"Internal fire syndrome\" \\\u003C10 in Diagnostic Scale for Syndrome Elements of Ischemic Stroke",{"label":16,"type":10,"description":10,"interventionNames":10},"Healthy subjects",[18],{"name":19,"role":20,"phone":21,"phoneExt":10,"email":22},"Xinxing Lai","CONTACT","8615901111280","new-star@163.com",[24],{"facility":25,"status":26,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Dongzhimen Hospital","RECRUITING","Beijing","Beijing Municipality","100700","China","CN",{"type":33,"coordinates":34},"Point",[35,36],116.39723,39.9075,{"lat":36,"lon":35},[39],{"name":40,"role":20,"phone":41,"phoneExt":10,"email":22},"Xinxing Lai, M.D.","15901111280",{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ying Gao","Professor","100487377","molecular-network-characteristics-of-phlegm-heat-syndrome-in-ischemic-stroke-based-on-multi-omics-integrated-analysis-100487377",false,"NCT05626296","Molecular Network Characteristics of Phlegm-heat Syndrome in Ischemic Stroke Based on Multi-omics Integrated Analysis","Inclusion Criteria:\n\n* Acute ischemic stroke, were confirmed by magnetic resonance imaging (MRI).\n* Symptom onset within 72 hours.\n* Diagnosis of phlegm-heat syndrome or non-phlegm-heat syndrome.\n* Male or female ≥ 50 years and ≤ 80 years.\n* With written informed consent.\n\nExclusion Criteria:\n\n* Planned or already receiving intravenous thrombolysis or endovascular treatment.\n* Acute infectious diseases or acute exacerbations of chronic diseases within one month before enrollment.\n* Patients with previous stroke.\n* Renal or hepatic insufficiency, tumors, immune diseases, severe underlying diseases.\n* Other conditions that may affect the collection and evaluation of clinical information (e.g., severe aphasia, mental illness).",true,"ALL","50 Years","80 Years",{"count":57,"type":58},24,"ESTIMATED","OBSERVATIONAL","The molecular characteristics of ischemic stroke with phlegm-heat syndrome and candidate biomarkers were identified based on multi-omics data. The main purpose of this study is to validate the molecular characteristics and biomarkers of phlegm-heat syndrome in ischemic stroke, and to demonstrate the association of biomarkers with clinical outcomes.",[62],"Ischemic Stroke, Acute","2024-06-17",{"date":65,"type":66},"2024-06-20","ACTUAL",{"date":68,"type":66},"2022-11-14",{"date":70,"type":58},"2024-12-31",{"name":5,"class":6},1]