[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100489188":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":31,"responsibleParty":54,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":69,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Region Skane","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with HPV-positive OPC",null,"Patients with HPV-positive OPC. They will provide blood samples before during and after treatment to evaluate treatment response and for early detection of recurrence",[13],"Diagnostic Test: Blood sample",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Blood sample","Blood samples for analysis of circulating tumour HPVDNA",[9],[21],{"name":22,"affiliation":23,"role":24},"Johanna Sjövall, MD,PhD","Dept. of clincial sciences, Lund University","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Johanna Sjövall, MD, PhD","CONTACT","+4646172164","johanna.sjovall@med.lu.se",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Dept. of ORL-HNS","RECRUITING","Lund","Skåne County","22185","Sweden","SE",{"type":41,"coordinates":42},"Point",[43,44],13.19321,55.70584,{"lat":44,"lon":43},[47,50],{"name":48,"role":28,"phone":49,"phoneExt":10,"email":30},"Johanna Sjovall, MD, PhD","+46707881716",{"name":51,"role":28,"phone":52,"phoneExt":10,"email":53},"Maria Gebre-Medhin, MD, PhD","+46730888266","maria.gebre-medhin@med.lu.se",{"type":55,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100489188","monitoring-and-early-response-evaluation-using-hpv-dna---a-study-on-patients-with-hpv-positive-throat-cancer-mer-hpv-100489188",false,"NCT05649865","Monitoring and Early Response Evaluation Using HPV DNA - A Study on Patients With HPV-positive Throat Cancer (MER-HPV)","Analysis of HPV DNA in Plasma in Patients With HPV-positive Oropharyngeal Squamous Cell Carcinoma - a Prospective Study of HPV DNA Levels for Treatment Response and Surveillance","MER-HPV","Inclusion Criteria:\n\n1. Only patients with an HPV-positive primary tumour will eventually be eligible for inclusion.\n\n   Non-detectable ctHPVDNA at diagnosis will not be a reason for exclusion.\n2. Age \\>18 years.\n3. Able to give informed consent.\n4. The patient will be treated with curative intent.\n\nExclusion Criteria:\n\nPatients with a short life expectancy, psychiatric or addictive disorders, or other medical conditions which might impair patient compliance may be excluded at the discretion of the investigator.","ALL","18 Years",{"count":67,"type":68},150,"ESTIMATED","3 Years","OBSERVATIONAL","The goal of this clinical trial is to determine the value of circulating tumour HPV DNA (human papilloma virus DNA found in the blood) at diagnosis, during treatment, and in the follow-up of patients diagnosed and treated for throat cancer caused by HPV.\n\nThe main question to answer is if the presence of HPV DNA in the blood one month after the treatment is useful in detecting remaining tumour or relapse within two years after treatment.\n\nThe participants will be asked to provide blood tests:\n\n1. before treatment\n2. weekly during the treatment\n3. on all scheduled follow-up appointments\n4. on all unplanned appointments where a relapse is suspected",[73],"Oropharynx Squamous Cell Carcinoma",[75,76],"Human papilloma virus","circulating HPV DNA","2023-06-07",{"date":79,"type":80},"2023-06-08","ACTUAL",{"date":82,"type":80},"2023-05-15",{"date":84,"type":68},"2028-05",{"name":5,"class":6},1]