[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588716":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":10,"locations":19,"responsibleParty":41,"collaborators":44,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":49,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":73,"overallStatus":22,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Wageningen University and Research","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"General cohort",null,"Women aged 18-55 years of age living with obesity (BMI =\\> 30kg\u002Fm2) undergoing either surgical (RYGB, OAGB, SG) or pharmacological obesity treatment.",{"label":13,"type":10,"description":14,"interventionNames":10},"Birth cohort","Pregnant women aged 18-45 years of age having received prior obesity treatment, either surgical (RYGB, OAGB, SG) or pharmacological for at least 4 months under medical supervision (any type)",[16],{"name":17,"affiliation":5,"role":18},"Agnes Berendsen, PhD","PRINCIPAL_INVESTIGATOR",[20],{"facility":21,"status":22,"city":23,"state":24,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Rijnstate Elst, Vitalys","RECRUITING","Elst","Gelderland","6662 NC","Netherlands","NL",{"type":29,"coordinates":30},"Point",[31,32],5.84167,51.91917,{"lat":32,"lon":31},[35,40],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Laura Heusschen, PhD","CONTACT","+31628527800","lheusschen@rijnstate.nl",{"name":10,"role":37,"phone":10,"phoneExt":10,"email":39},{"type":18,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Agnes Berendsen","Assistant Professor",[45],{"name":46,"class":6},"Rijnstate Hospital","100588716","monitoring-nutritional-consequences-of-obesity-treatment-on-womens-health-100588716",false,"NCT06945016","Monitoring Nutritional Consequences of Obesity Treatment on Women's Health","MOnitoring NUtritional COnsequences of Obesity Treatment on Women's Health and Transgenerational Effects for Healthier Future Generations: a Multicentre Prospective Observational Cohort Study","MONUCO","General Inclusion Criteria:\n\n* Female sex at birth\n* Aged 18-55 years of age\n* Living with obesity (BMI ≥ 30 kg\u002Fm2)\n* Approved for obesity treatment in one of the participating hospitals:\n* Undergoing primary bariatric surgery (RYGB, OAGB or SG)\n* Receiving obesity medication (any type) with a BMI ≥30 kg\u002Fm2 under medical supervision.\n* For those undergoing MRI, DEXA and quantitative ultrasound scan: Willing to be informed about incidental findings of pathology and approving of reporting this to their general physician.\n\nAdditional inclusion criteria for birth cohort:\n\n* Being pregnant\n* Age 18-45 years of age\n* Having received prior obesity treatment, either surgical (RYGB, OAGB, SG) or pharmacological for at least 4 months under medical supervision (any type).\n\nGeneral Exclusion Criteria:\n\n* Male sex at birth\n* Aged \\\u003C18 or \\>55 years of age\n* BMI \\\u003C30 kg\u002Fm2\n* Not able to read and\u002For write in Dutch\n* Undergoing a revisional or secondary bariatric procedure (excluding previous gastric banding)\n* Malnutrition due to other chronic condition, specifically malignancy, substance abuse\n* (mental) condition that makes it impossible to fill out a questionnaire correctly.\n* For those undergoing a DEXA scan: height \\>196 cm or weight \\>160 kg\n* For those undergoing a MRI scan: having a contra-indication to MRI scanning including (but not limited to) pacemakers and defibrillators, intraorbital or intraocular metallic fragments, ferromagnetic implans or claustrophobia.\n\nAdditional exclusion criteria birth cohort:\n\n* Aged \\\u003C18 or \\>45 years of age\n* \\>25 weeks of gestation\n* Multiple pregnancy\n* Reversal of the bariatric procedure","FEMALE","18 Years","55 Years",{"count":59,"type":60},1150,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate the long-term effect of obesity treatments on the health of women. This study will specifically focusses on the effects on nutritional intake, nutritional status, musculoskeletal health and reproductive health. Additionally, this study will also investigate the effect of obesity treatment on pregnancy outcomes and child development.\n\nTo achieve the goal of this study, participants already receiving either surgical treatment for obesity or treatment with anti-obesity medication as part of their regular medical care will fill in additional questionnaires, provide blood, urine and feces samples, and undergo additional measurements of body composition and muscle strength up to for 10 years.",[64,65,66,67,68,69,70,71,72],"Obesity and Obesity-related Medical Conditions","Bariatric Surgery","Anti-obesity Agents","Body Composition","Muscle Strength","Reproductive Health","Mental Health","Pregnancy","Nutritional Status",[74,75,76,77,78,79,80,81],"cohort","obesity treatment","obesity","Bariatric surgery","anti-obesity agents","body composition","nutrition","observational","2025-07-06",{"date":84,"type":85},"2025-07-10","ACTUAL",{"date":87,"type":85},"2025-01-28",{"date":89,"type":60},"2040-01-28",{"name":5,"class":6},1]