[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100357522":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":26,"centralContacts":31,"locations":39,"responsibleParty":55,"collaborators":7,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":7,"enrollmentInfo":66,"targetDuration":7,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":41,"whyStopped":7,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Centre Hospitalier Universitaire, Amiens","OTHER",null,[9,13,16,19,22],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"BIOLOGICAL","glucose measurement","Glucose values will be recorded during 5 days as following : every hour at day 0, every 2 hours at day 1, every 3 hours at days 2 to 5.",{"type":10,"name":14,"description":15,"armGroupLabels":7,"otherNames":7},"lactacte measurement","Lactate values will be recorded during 5 days as following : every hour at day 0, every 2 hours at day 1, every 3 hours at days 2 to 5.",{"type":10,"name":17,"description":18,"armGroupLabels":7,"otherNames":7},"pyruvate measurement","pyruvate values will be recorded during 5 days as following : every hour at day 0, every 2 hours at day 1, every 3 hours at days 2 to 5.",{"type":10,"name":20,"description":21,"armGroupLabels":7,"otherNames":7},"glycerol measurement","glycerol values will be recorded during 5 days as following : every hour at day 0, every 2 hours at day 1, every 3 hours at days 2 to 5.",{"type":23,"name":24,"description":25,"armGroupLabels":7,"otherNames":7},"PROCEDURE","Bone free flap monitoring","Bone free flaps will be monitored with a microdialysis catheter directly positioned in bone tissue.",[27],{"name":28,"affiliation":29,"role":30},"Stéphanie Dakpe, MD","CHU Amiens","PRINCIPAL_INVESTIGATOR",[32,36],{"name":28,"role":33,"phone":34,"phoneExt":7,"email":35},"CONTACT","(33)322089050","dakpe.stephanie@chu-amiens.fr",{"name":37,"role":33,"phone":34,"phoneExt":7,"email":38},"Sylvie Testelin, Pr","testelin.sylvie@chu-amiens.fr",[40],{"facility":29,"status":41,"city":42,"state":7,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Amiens","80480","France","FR",{"type":47,"coordinates":48},"Point",[49,50],2.3,49.9,{"lat":50,"lon":49},[53,54],{"name":28,"role":33,"phone":34,"phoneExt":7,"email":35},{"name":37,"role":33,"phone":34,"phoneExt":7,"email":38},{"type":56,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100357522","monitoring-of-the-bone-free-flaps-with-microdialysis-100357522",false,"NCT03935139","Monitoring of the Bone Free Flaps With Microdialysis","MTM2018","Inclusion Criteria:\n\n* adult person\n* signed informed consent\n* head and neck reconstruction with iliac crest or fibula free flap\n* patient covered by national health insurance\n\nExclusion Criteria:\n\n* minor person\n* head and neck reconstruction with other types of free flaps than crest or fibula free flap\n* pregnant or breastfeeding women","ALL","18 Years",{"count":67,"type":68},40,"ESTIMATED","INTERVENTIONAL",[71],"NA","Microdialysis is admitted to be reliable by numerous surgeons to monitor flaps. Nevertheless, a few authors reported follow up with microdialysis in bone free flaps, and they all describe the position of the catheter in the surrounding soft tissue muscle which is not the accurate reflect of bone vascularisation. The aim of this study is to determine the lactate\u002Fpyruvate ratio mean value in bone free flaps with a microdialysis catheter directly positioned in the bone tissue.",[74],"Flap Necrosis",[76,77,78,79],"microdialysis","bone free flap","fibula","iliac crest","2024-07-09",{"date":82,"type":83},"2024-07-10","ACTUAL",{"date":85,"type":83},"2019-07-22",{"date":87,"type":68},"2025-07",{"name":5,"class":6},1]