[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590717":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":31,"locations":37,"responsibleParty":49,"collaborators":25,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":78,"overallStatus":87,"whyStopped":25,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sodium Hypochlorite Group","EXPERIMENTAL","Participants in this group will receive root canal irrigation using sodium hypochlorite during pulpectomy of nonvital primary molars. A 3 mL solution will be used per canal following standard clinical procedures.",[13],"Drug: Sodium hypochlorite",{"label":15,"type":10,"description":16,"interventionNames":17},"Moringa oleifera Leaf Extract Group","extract of Moringa oleifera leaves prepared as a solution, used as a natural antimicrobial root canal irrigant.",[18],"Biological: Moringa Oleifera Leaf Extract",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Sodium hypochlorite","sodium hypochlorite solution will be used as a root canal irrigant during pulpectomy in primary molars. A volume of 3 mL will be delivered into each canal using a syringe with a side-vented needle. Irrigation will be followed by microbial sampling for blood agar",[9],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"BIOLOGICAL","Moringa Oleifera Leaf Extract","extract of Moringa oleifera leaves will be used as an intracanal irrigant during pulpectomy. A volume of 3 mL will be used per canal, and post-irrigation microbial samples will be analyzed using the same methods as the control group.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Alawi Taha Alaidarous T Principal Investigator, BDS","CONTACT","+966500969988","al-alawi.ta@hotmail.com",[38],{"facility":39,"status":25,"city":40,"state":25,"zip":25,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":25},"Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University","Cairo","Egypt","EG",{"type":44,"coordinates":45},"Point",[46,47],31.24967,30.06263,{"lat":47,"lon":46},{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Alawi Taha A Alaidarous","Principal Investigator","100590717","moringa-oleifera-vs-sodium-hypochlorite-for-root-canal-irrigation-in-nonvital-primary-molars-100590717",false,"NCT06971055","Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars","Evaluation of Antimicrobial Efficacy of Moringa Oleifera Leaf Extract Versus Sodium Hypochlorite as Root Canal Irrigants in Pulpectomy of Nonvital Primary Molars: A Randomized Clinical Trial","MORvNAOCL","Inclusion Criteria:\n\n* Children aged 4 to 7 years\n* Clinically and radiographically diagnosed with nonvital primary molars requiring pulpectomy\n* Cooperative children who can undergo dental treatment\n* Healthy-appearing children with no systemic, physical, or mental disorders\n\nExclusion Criteria:\n\n* Medically compromised or uncooperative children\n* Primary molars indicated for extraction due to:\n* Advanced root resorption (more than two-thirds)\n* Teeth near exfoliation\n* Deep subgingival caries preventing proper restoration\n* Excessive mobility (Miller's Grade 2 or higher)",true,"ALL","4 Years","7 Years",{"count":66,"type":67},38,"ESTIMATED","INTERVENTIONAL",[70],"NA","This randomized clinical trial aims to evaluate and compare the antimicrobial efficacy of Moringa Oleifera leaf extract versus sodium hypochlorite as root canal irrigants in pulpectomy of nonvital primary molars in pediatric patients. The study will assess bacterial reduction using blood agar",[73,74,75,76,77],"Dental Caries","Pulp Necrosis","Primary Tooth Pulpectomy","Pediatric Dentistry","Endodontic Infection",[79,22,80,81,82,83,84,85,86],"Moringa oleifera","Root canal irrigants","Pulpectomy","Primary molars","Enterococcus faecalis","Antimicrobial efficacy","Pediatric endodontics","Coagulase-Negative Staphylococci","NOT_YET_RECRUITING","2025-05-29",{"date":90,"type":91},"2025-06-03","ACTUAL",{"date":93,"type":67},"2025-07-20",{"date":95,"type":67},"2026-01-01",{"name":5,"class":6},1]