[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615591":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":26,"locations":26,"responsibleParty":27,"collaborators":26,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":26,"eligibilityCriteria":37,"healthyVolunteers":33,"sex":38,"minAge":39,"maxAge":40,"enrollmentInfo":41,"targetDuration":26,"studyType":44,"phases":45,"briefSummary":47,"conditions":48,"keywords":50,"overallStatus":54,"whyStopped":26,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":26},{"fullName":5,"class":6},"Yarmouk University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Morning patching","EXPERIMENTAL","Daily occlusion: 2 hours\u002Fday between 08:00-10:00.\n\nDuring patching: child performs near-vision activities (e.g. reading, puzzles, coloring).\n\nDuration: 6 months (unless withdrawal criteria met).",[13],"Behavioral: eye-patching",{"label":15,"type":10,"description":16,"interventionNames":17},"Evening patching","Daily occlusion: 2 hours\u002Fday between 17:00-19:00.\n\nDuring patching: same near-vision tasks as Arm 1.\n\nDuration: 6 months (unless withdrawal criteria met).",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","eye-patching","is a non-invasive treatment for Amblyopia (\"lazy eye\") in children. It involves covering (patching) the stronger, \"good\" eye so that the weaker (amblyopic) eye is forced to work. This encourages the brain to rely on the amblyopic eye, helping to strengthen its visual pathways.",[15,9],[25],"occlusion therapy",null,{"type":28,"investigatorFullName":29,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Rami Alomari","Associate professor","100615591","morning-versus-evening-patching-in-childhood-amblyopia-100615591",false,"NCT07294599","Morning Versus Evening Patching in Childhood Amblyopia","Morning Versus Evening Patching in Childhood Amblyopia-A Randomized Clinical Trial","Inclusion Criteria:\n\n* Age: 4-8 years.\n* Unilateral amblyopia.\n* Amblyopic-eye BCVA decimal 0.17-0.67 (≈ 6\u002F36-6\u002F9).\n* Fellow-eye BCVA ≥ 0.80 decimal (≈ 6\u002F7.5 or better).\n* Amblyopia type: refractive-dominant or strabismic\u002Fmixed.\n* Parent\u002Fguardian consent obtained.\n\nExclusion Criteria:\n\n* Bilateral amblyopia.\n* Sensory-deprivation amblyopia (e.g., due to congenital cataract, ptosis, corneal opacity).\n* Ocular surgery within the past 6 months, or planned surgery during study.\n* Likely poor adherence (e.g., due to social, logistic, or family constraints).","ALL","4 Years","8 Years",{"count":42,"type":43},100,"ESTIMATED","INTERVENTIONAL",[46],"NA","To determine whether the time of day at which daily occlusion (patching) is administered - morning (08:00-10:00) versus evening (17:00-19:00) - affects the amount of visual-acuity improvement in the amblyopic eye in children with unilateral amblyopia.\n\nRationale:\n\nWhile occlusion therapy remains the mainstay for treatment of childhood amblyopia, existing trials have focused on patching duration, not on the timing of occlusion. Diurnal or chronobiological factors - such as fluctuations in neuroplasticity, attention, compliance, or visual demand during the day - may influence the efficacy of patching. Understanding whether timing matters could help optimize occlusion therapy, improve outcomes, and reduce treatment burden.",[49],"Amblyopia",[9,15,49,51,52,53],"Clinical trial","Anisometriopia","Strabismus","NOT_YET_RECRUITING","2025-12-18",{"date":57,"type":58},"2025-12-26","ACTUAL",{"date":60,"type":43},"2025-12-14",{"date":62,"type":43},"2026-06-14",{"name":5,"class":6}]