[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562162":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":42,"locations":50,"responsibleParty":72,"collaborators":74,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":89,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":12,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":105,"overallStatus":53,"whyStopped":12,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,13,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of care treatment and follow-up schedule without alteration (control arm)","NO_INTERVENTION","This arm with serve as the control arm and receive the current standard of care, which is no caregiver training to conduct mid-upper arm circumference screenings and monthly clinic-based follow-up appointments for 3 months with a final visit at 6 months post enrollment.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Caregiver mid-upper arm circumference (MUAC) screening and a standard of care follow-up schedule","EXPERIMENTAL","This arm will include caregiver screening with a mid-upper arm circumference tape at home weekly. Caregivers will be trained to screen their child for malnutrition relapse using mid-upper arm circumference tapes and requested to bring their child back to the clinic when relapse is detected. Additionally, this arm will receive the standard of care, which includes a monthly follow-up schedule for the first 3 months post enrollment and a final follow-up at 6 months.",[18],"Behavioral: Training caregivers to screen children for malnutrition relapse",{"label":20,"type":15,"description":21,"interventionNames":22},"Caregiver mid-upper arm circumference (MUAC) screening and a reduced follow-up schedule","This arm will include caregiver screening with a mid-upper arm circumference tape at home weekly. Caregivers will be trained to screen their child for malnutrition relapse using mid-upper arm circumference tapes and requested to bring their child back to the clinic when relapse is detected. Additionally, this arm will receive a reduced follow-up schedule at the clinic, which will include one planned visit at 3 months post enrollment and a final follow-up visit at 6 months.",[18,23],"Other: Reduced follow-up schedule",[25,32],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","Training caregivers to screen children for malnutrition relapse","Caregivers enrolled in the trial who are assigned to the two experimental arms, will be provided mid-upper arm circumference tapes and trained on how to screen their child for malnutrition relapse and asked to bring their child back to the clinic if relapse is detected.",[20,14],[31],"Caregiver and\u002For mother mid-upper arm circumference screening",{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"Reduced follow-up schedule","Caregivers in one of the caregiver mid-upper arm circumference screening arms, will be asked to adhere to a reduced follow-up clinic visit schedule for when they bring their child to the clinic for planned visits. The standard of care includes monthly visits for the first 3 months post recovery, but those randomized to the reduced follow-up schedule arm, will not bring their child to the clinic for planned visits 1 month and 2 months after baseline.",[20],[37],"Reduced clinic visits",[39],{"name":40,"affiliation":5,"role":41},"Catherine Oldenburg, ScD","PRINCIPAL_INVESTIGATOR",[43,47],{"name":40,"role":44,"phone":45,"phoneExt":12,"email":46},"CONTACT","415-502-8843","catherine.oldenburg@uscf.edu",{"name":48,"role":44,"phone":12,"phoneExt":12,"email":49},"Hadley Burroughs","hadley.burroughs@ucsf.edu",[51],{"facility":52,"status":53,"city":54,"state":12,"zip":12,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Centre de recherche en sante de nouna","RECRUITING","Nouna","Burkina Faso","BF",{"type":58,"coordinates":59},"Point",[60,61],-3.86305,12.72939,{"lat":61,"lon":60},[64,68],{"name":65,"role":44,"phone":66,"phoneExt":12,"email":67},"Ali Sie, MD, PHD","+226 70 20 47 78","sieali@yahoo.fr",{"name":69,"role":44,"phone":70,"phoneExt":12,"email":71},"Mamadou Bountogo, MD, PHD","+226 70 39 89 44","drbountogo@yahoo.fr",{"type":73,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR",[75,78],{"name":76,"class":77},"Centre de Recherche en Sante de Nouna, Burkina Faso","OTHER_GOV",{"name":79,"class":6},"Thrasher Research Fund","100562162","mother-screening-for-relapse-using-mid-upper-arm-circumference-among-children-recovered-from-severe-acute-malnutrition-full-scale-trial-100562162",false,"NCT06599580","Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition (Full Scale Trial)","Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition (MAMAN)","MAMAN","Inclusion Criteria:\n\n* Caregiver's aged 18 years old or older or a legal guardian or a relative aged 18 or older\n* Child aged 6-54 months\n* Child has recovered from an episode of severe acute malnutrition per Burkinabè national guidelines (weight-for-height ≥ -2 and\u002For mid-upper arm circumference ≥ 12.5 cm in the past month, with the criterion used for admissions corresponding to the original admission criteria)\n* Family is planning to stay in the study area for 6 months\n* Appropriate consent from the caregiver or guardian.\n\nExclusion Criteria:\n\n* Caregiver age under 18 years old, or legal guardian or relatives under 18 years old\n* Child age \\\u003C 6 months or \\> 54 months\n* Twins\u002Fmultiple births\n* Children with feeding issues\n* Did not recover from severe acute malnutrition in the past month\n* Family is planning to move out of the study area in the next 6 months\n* Caregiver or guardian refuses to provide consent",true,"ALL","6 Months","54 Months",{"count":93,"type":94},2400,"ESTIMATED","INTERVENTIONAL",[97],"NA","A 1:1:1 individually randomized unmasked controlled trial is proposed in which caregivers will be trained to screen their children who have recovered from an episode of SAM (severe acute malnutrition) using MUAC (mid-upper arm circumference) tapes. One arm will include caregiver screening with a mid-upper arm circumference tape and usual monthly follow-up schedule for the first 3 months post enrollment and a final follow-up at 6 months. Another arm will include caregiver screening with a mid-upper arm circumference tape and a reduced follow-up schedule for one visit at 3 months and a final visit at 6 months. The third arm will adhere to the current standard of care, which is no caregiver training to conduct mid-upper arm circumference screenings and monthly clinic-based follow-up appointments for 3 months with a final visit at 6 months post enrollment. Children aged 6-54 months with a documented recovery from uncomplicated severe acute malnutrition that was managed in a participating outpatient nutritional program and their caregivers will be eligible for inclusion in the trial. Caregivers will be trained to screen their children weekly for 6 months following discharge from the nutritional program and will be counseled to bring their child back to the nutritional program should their mid-upper arm circumference value fall in the red zone of the mid-upper arm circumference tape (\\\u003C 11.5 cm). All children will be seen at 3 and 6 months for the primary outcome assessment. By conducting this study, our primary goal is to determine if training caregivers to screen their children for relapse to MAM (moderate acute malnutrition) or SAM (severe acute malnutrition) using mid-upper arm circumference tapes following recovery from SAM (severe acute malnutrition) will reduce the risk of relapse. An additional aim is to assess the level of acceptability of caregivers screening children for malnutrition using mid-upper arm circumference tapes from both a clinic and caregiver perspective.",[100,101,102,103,104],"Malnutrition, Child","Malnutrition, Infant","Malnutrition or Risk of Malnutrition","Hemoglobin Level Measurement","Anemia",[106,107,108,109],"MUAC (mid-upper arm circumference)","Caregiver screening","malnutrition","home based malnutrition screening","2025-11-17",{"date":112,"type":113},"2025-11-20","ACTUAL",{"date":115,"type":113},"2025-03-20",{"date":117,"type":94},"2027-11",{"name":5,"class":6},1]