[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100493184":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":10,"centralContacts":10,"locations":22,"responsibleParty":41,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":51,"minAge":52,"maxAge":10,"enrollmentInfo":53,"targetDuration":10,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":10,"overallStatus":25,"whyStopped":10,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"Fondation Ophtalmologique Adolphe de Rothschild","NETWORK",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"cases : patients with chronic pain",null,[12],"Other: reward learning task",{"label":14,"type":10,"description":10,"interventionNames":15},"controls",[12],[17],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"OTHER","reward learning task","during usual follow-up patients will complete a remard learning task questionnaire. This questionnaire cannot be assimilated to a clinical intervention.",[9,14],[23],{"facility":24,"status":25,"city":26,"state":10,"zip":10,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"Hôpital Fondation Adolphe de Rothschild","RECRUITING","Paris","France","FR",{"type":30,"coordinates":31},"Point",[32,33],2.3488,48.85341,{"lat":33,"lon":32},[36],{"name":37,"role":38,"phone":39,"phoneExt":10,"email":40},"Amélie YAVCHITZ","CONTACT","+3314836454","ayavchitz@for.paris",{"type":42,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100493184","motivational-behavioral-and-functional-mri-impairment-in-patients-with-chronic-neuropathic-pain-100493184",false,"NCT05701852","Motivational Behavioral and Functional MRI Impairment in Patients With Chronic Neuropathic Pain","MOTION","Inclusion Criteria:\n\n* For cases: patients managed in the neurosurgery department or at CETD for chronic neuropathic pain, of central or peripheral origin.\n* For controls: matched to a case on age (±5 years) and sex\n\nExclusion Criteria:\n\n* Neurodegenerative or inflammatory neurological pathology\n* Clinical depressive syndrome\n* High doses of opioid treatment (greater than 100 mg\u002Fday of morphine equivalent)\n* Impaired judgment or inability to receive information that does not allow the performance of behavioral tasks\n* Absolute contraindication to MRI (e.g. pacemaker, implantable pacemaker, metallic intra-orbital foreign body)",true,"ALL","18 Years",{"count":54,"type":55},50,"ESTIMATED","OBSERVATIONAL","The main hypothesis of this study is that the alteration of the reward circuitry underlying the motivational deficit in chronic pain patients compared to healthy subjects results in a decrease in the capacity for reward learning. The fMRI studies have shown that this type of learning depends on the dopaminergic system innervating key regions of the reward system.",[59],"Chronic Pain","2025-12-30",{"date":62,"type":63},"2026-01-05","ACTUAL",{"date":65,"type":63},"2023-12-19",{"date":67,"type":55},"2027-05",{"name":5,"class":6},1]